Gene Information

Name : Intca_1035 (Intca_1035)
Accession : YP_004098285.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1143121 - 1144704 bp
Length : 1584 bp
Strand : +
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR000991: IPR001674: IPR017926: IPR004739: IPR 011702: IPR006220: IPR001317; KEGG: kse:Ksed_07680 GMP synthase (glutamine-hydrolyzing); PFAM: GMP synthase domain protein; glutamine amidotransfe

DNA sequence :
GTGAGTGAAGCGCACGACCTCCAGGCCCACCCCGTCATCGTCGTCGACTTCGGCGCCCAGTACGCACAGCTGATCGCGAG
GCGGGTCCGCGAGGCGCAGGTCTACAGCGAGGTGGTGCCGCACTCGATCTCGGCCGCCGAGATCCTCGCCAAGGAGCCCG
CCGCGATCATCCTCTCCGGCGGGCCGAGCTCTGTCTACGAGGACGGGGCCCCGCGGCTCGACGCGGCGCTGCTCGACGCA
GGCGTGCCGGTGTTCGGTATGTGCTACGGCTTCCAGGCGATGGCTCAGGCGCTCGGCGGGACGGTGGACCGCACCGGAGC
GAGGGAGTACGGCAAGACCCAGGCGTCCATCTCACGCACCGACTCCACCCTCTTCGACGGCCAGCCGGAGGAGCAGGTCG
TGTGGATGTCGCACGGAGACTCGGTGGGCGAGGTTCCGGACGGCTTCCGCGTCACGGCCTCCACCCTGAGCACGCCGGTC
GCCGCCTTCGAGAACGACGAGCAGCGGCTCTATGGCGTGCAGTGGCACCCCGAGGTGCTGCACTCCGAGCAGGGCCAGCG
GGTGCTCGAGAACTTCCTCCGCAGGGGCGCCGGGATCACCCCCGAGTGGACGCCCGGCAACGTCGTCGACGAGCTCGTCG
AGTCGATCCGGGACCAGGTCGGCGAGGACCGGGTGCTCTGTGCGCTCTCCGGCGGCGTCGACTCCTCGGTGGCGGCGGCC
CTCGTCCAGCGGGCCGTCGGTGACCAGCTCACCTGCGTCTTCGTCGACCACGGGCTGCTCCGCGAGGGCGAGGCCGAGCA
GGTCGAGAAGGACTTCGTCGAGGCGACCGGCGTCGACCTCGTCGTCGTCGACGCCCAGGAGCGGTTCCTCACGGCGCTCG
CCGGGGTCACCGAGCCCGAGGCCAAGCGCAAGATCATCGGCGAGCAGTTCATCCGGGTCTTCGAGCAGGCCGCCCGCGAC
GTCGTCGGTTCGCACGCCGACGAGGAGCACCCCGTCAAGTGGCTCGTGCAGGGCACGCTCTATCCCGATGTCGTCGAGTC
GGGTGGTGGCGAGGGCGCGGCCAACATCAAGAGCCACCACAACGTCGGTGGCCTGCCGGACGATCTGCAGTTCAAGCTGA
TCGAGCCGTTGCGCACCCTGTTCAAGGACGAGGTCAGGCAGGTCGGGCTCGAGCTCGGCGTGCCCGAGGTCATCGTCTGG
CGACAGCCGTTCCCCGGTCCGGGGCTCGGGATCCGCATCATCGGGGCGGTCGACGCCGAGCGGCTCGCCATCCTCCGCCG
CGCCGACGCCATCGCCCGCGACGAGCTGACGAAGGCGGGGCTCGACCGCGACATCTGGCAGTGCCCGGTCGTCCTCCTCG
CCGACGTCCGCTCGGTCGGGGTCCAGGGCGACTTCCGCACCTACGGACACCCGGTCGTGCTGCGCCCGGTCGCCTCGGAG
GACGCGATGACGGCCGACTGGGCCCGCGTCCCCTACGAGGTGCTCGCCCAGATCTCGACGCGCATCACCAACGAGGTGAC
CGAGGTCAACCGGGTCGTGCTCGACGTGACGAGCAAGCCCCCGGGCACCATCGAGTGGGAGTAG

Protein sequence :
MSEAHDLQAHPVIVVDFGAQYAQLIARRVREAQVYSEVVPHSISAAEILAKEPAAIILSGGPSSVYEDGAPRLDAALLDA
GVPVFGMCYGFQAMAQALGGTVDRTGAREYGKTQASISRTDSTLFDGQPEEQVVWMSHGDSVGEVPDGFRVTASTLSTPV
AAFENDEQRLYGVQWHPEVLHSEQGQRVLENFLRRGAGITPEWTPGNVVDELVESIRDQVGEDRVLCALSGGVDSSVAAA
LVQRAVGDQLTCVFVDHGLLREGEAEQVEKDFVEATGVDLVVVDAQERFLTALAGVTEPEAKRKIIGEQFIRVFEQAARD
VVGSHADEEHPVKWLVQGTLYPDVVESGGGEGAANIKSHHNVGGLPDDLQFKLIEPLRTLFKDEVRQVGLELGVPEVIVW
RQPFPGPGLGIRIIGAVDAERLAILRRADAIARDELTKAGLDRDIWQCPVVLLADVRSVGVQGDFRTYGHPVVLRPVASE
DAMTADWARVPYEVLAQISTRITNEVTEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-169 69
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-136 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-136 54