Gene Information

Name : Intca_0990 (Intca_0990)
Accession : YP_004098241.1
Strain : Intrasporangium calvum DSM 43043
Genome accession: NC_014830
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1098312 - 1099490 bp
Length : 1179 bp
Strand : +
Note : COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_0976 cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: cystathionine gamma-synthase; PFAM: Cys/Met metab

DNA sequence :
ATGTCTGACGAGCACGGATTCTCGACGCGCGCCATCCACGCAGGCCAGGAGGCCGACGCCTCGACCGGTGCGGTCGTCCC
GCCGATCTACCAGGTCTCGACGTACAAGCAGGACGGCATCGGCGGCTTCCGCGGCGGCTACGAGTACAGCCGGTCGGCCA
ACCCCACCCGGACGGCGCTCGAGGAGTGCATCGCTGCGCTCGAAGGCGGCAGCCGCGGCTTCGCCTTCGCGTCCGGGCTC
GCCGGGCAGGACTGTGTCGTGCGGTCGCTGCTCGTGCCCGGCGACCACGTCGTCGTGCCGAGCGATGCCTACGGCGGGAC
CTACCGCTACTTCAACAAGGTCGCGAAGCCGCACGGGATCGACCACTCGATCGCGAGGATCGGCGACGTCGACGCCGTGC
GGGACGCCATCGTGCCGGGCCGCACCAAGATGGTGTGGGTCGAGACGCCGACCAACCCGCTGCTCGGCATCGCCGACATC
GAGGCGATCGCCGAGGTCGCCCACGACGCCGGGGCGGTGCTCGTCGTCGACAACACCTTCGCGACCGCCTACCTGCAGAA
CCCGATCGCCCTCGGCGCCGACATCGTCACCCACTCGACGACCAAGTACTCCGGTGGCCACAGCGACGTCGTCGGGGGCG
CGGTCGTCACTGCACCGCAGATCCGCGTCGCCGGGCTCGAGGACGCCGAGGAGCGGATCGCCTTCCACCAGAACTCGATC
GGTGGAGTCGCCGGCCCCTTCGACTCGTGGCTCACGCTGCGCGGGCTGAAGACTCTCGCGGTGCGCATGGAGCGCCACTG
CGACAACGCCGAGCGGGTCGTCGAGTTCCTGACCGGTCACGACGGCGTGGCGCAGGTGTTCTACCCCGGCCTCGAGTCGC
ACCACAACCACGCGGTCGCAGCGCGACAGATGAAGCGCTTCGGCGGCATGGTGTCCTTCCGGATGAGGAAGGGCGAGGAC
GCAGCCGTCAAGACCTGCGCCGCAGTCCAGCTCTGGACGCTCGGGGAGTCGCTCGGCGGCGTCGAGTCCCTCATCGAGCA
CCCGGCGCGGATGACCCACGCCTCGGTCGCCGGCACGGAGCTCGAGGTCCCCGCCGACCTCATCCGACTGTCGGTCGGCA
TCGAGGACGTGGACGACCTCATCGCCGACCTCCGTGAAGCACTCGACATCCACGGCTGA

Protein sequence :
MSDEHGFSTRAIHAGQEADASTGAVVPPIYQVSTYKQDGIGGFRGGYEYSRSANPTRTALEECIAALEGGSRGFAFASGL
AGQDCVVRSLLVPGDHVVVPSDAYGGTYRYFNKVAKPHGIDHSIARIGDVDAVRDAIVPGRTKMVWVETPTNPLLGIADI
EAIAEVAHDAGAVLVVDNTFATAYLQNPIALGADIVTHSTTKYSGGHSDVVGGAVVTAPQIRVAGLEDAEERIAFHQNSI
GGVAGPFDSWLTLRGLKTLAVRMERHCDNAERVVEFLTGHDGVAQVFYPGLESHHNHAVAARQMKRFGGMVSFRMRKGED
AAVKTCAAVQLWTLGESLGGVESLIEHPARMTHASVAGTELEVPADLIRLSVGIEDVDDLIADLREALDIHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-78 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-78 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Intca_0990 YP_004098241.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 2e-64 41