Gene Information

Name : Astex_3852 (Astex_3852)
Accession : YP_004089610.1
Strain :
Genome accession: NC_014819
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 150168 - 152171 bp
Length : 2004 bp
Strand : -
Note : KEGG: mes:Meso_4129 heavy metal translocating P-type ATPase; TIGRFAM: cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein;

DNA sequence :
ATGGCCCACGATTCCCACCCGCCCTCGAAGGCCGAGGGCAAGACCGGCGGCAAGGCCGCCAATGACGACGACCATAAGCA
CGGGGACGATCTGGAAGGTCTGCACGGCCACGACCACGGCCCGAGCGATGGACCGTGGTGGCAGAGCCCCAAGGCGCGCC
TGACGCTCCTGTGCGCCGCCGCCTTCGCTGTCGCCTTCCTTCTGGCCAAGCTCATACCGCAAAGTGCCCCTTGGGGCTAT
GTGGCGGCCATGATGGTCGGCCTGATCCCCATCGTTCGGCGCGCGGCCAAAGGCGTGGCGCGCGGCTACCCGTTCTCGAT
CGAGACCCTGATGACGATAGCGGCCATTGGCGCCATCGTCATCGATGCCGCCGAAGAGGCGGCTGTCGTCATCATCCTGT
TCCTCGTGGGTGAGTTGCTTGAGGGGATTGCGGCCGATCGGGCCCGGGCCAGTATCCGGGAGTTGGCGACACTTGTCCCC
AAGGACGCGCTCCTGGATGAGGGTGACGGCAAGACGCGCAAGGTGCCGGCTGAAGAGCTGGCGGTTGATGCCATAGTGGT
CGTGCGCCCCGGCGACCGCGTGCCGGCCGATGGCGTGATTGTCGAAGGCGAAAGCGCGATCGATGAGGCGCCGGTAACGG
GCGAGTCCGTGCCGAAGCGCAAGACGGTGGATGATCAGGTCTTTGCCGGGACGATCAATCAGGAAGGCGTGTTGCGTATC
AAGGTGACCGCTGCCGCCGAGAACAATACGATCTCCCGGGTGATCAAGCTCGTCGAGGATGCGCAGGAGGCCAAGGCGCC
GACCGAGCGCTTCATCGACGGCTTCTCCAAATATTACACCCCTGGGGTCATCGTTTTTGCGTTCCTCGTCACCGTCATTC
CGCCCCTGGCCTTTGGCGGTGACTGGTCGGAATGGCTCTACAAGGGCCTGGCTGTGCTTTTGATCGGGTGTCCCTGCGCG
CTGGTTATCTCGACGCCGGCCGCGATCGCAGCGGCGCTATCGGCCGGAGCCAAACGTGGACTTCTTATGAAGGGCGGCGC
GGTTCTGGAGACCTTCCGCAAGGTGACCTATGTCGCCATGGATAAGACCGGGACGCTGACCGAAGGCAAACCAAAGCTCA
CCGACATCCATGGCAATGGGATGGATGAGGGCGAGGTCTTGCGCATTGCCGCTACGCTTGAGGCGGGTTCGAGCCATCCG
CTCGCGACCGCTATCCTTAATGAAGCCAAGGCCCGTAATATCGACCATGGCACGGCTGAAAGCTCTAAGGCGGTGGCCGG
TAAGGGCGTTGCGGGTACGGTCGATGGCAAGTCCGTGCGCCTCTATTCACCCAAGGCGACCGAAGACTACATGCCGCTGG
GCGGCAATATGCGCCAAAGCATCCAGCGGCTGAATGACGAGGGCAAGACGGTGTCTGTCCTGATCGTCGATGACGAGATC
GCCGGCTTCATCGCCATGCGCGACGAGCCGCGCGAAGACGCCAAGGCCGGGGTATGGGCGCTGCAGCGTCAGGGCATCAC
CACGCTCATGCTGACGGGCGATAACAAGCGCACCGGTGAGGCCATCGCCTCGCAACTCGGCATGCAGGCTCGAACCGAGT
TGATGCCCGAAGAGAAGCAAATGATCGTCAAGGATCTGCAGGATCAGGGCGAGGTCGTCGCGAAGGTTGGTGACGGTATC
AACGATGCGCCGGCGCTTGCGGCCGCGGATGTCGGTATCGCCATGGGAGGCGGGACGGATGTGGCGCTGGAGACGGCTGA
TGCGGCCGTGCTGCATGGTCGTGTTATGGATATTGCCGACATGATCGGCCTCTCCAGGCTGACCATGACCAACATCTATC
AGAACATCACGATCGCACTCGGTCTGAAGGCCGTTTTTCTGGTCACAACGGTTCTGGGCATCACAGGGCTTTGGCCCGCG
ATTTTGGCGGACACAGGCGCGACGGTCTTCGTGACGGCCAATGCCATGCGGCTTCTGGGCTGGAAGGGGGGGCGCGATGC
TTAG

Protein sequence :
MAHDSHPPSKAEGKTGGKAANDDDHKHGDDLEGLHGHDHGPSDGPWWQSPKARLTLLCAAAFAVAFLLAKLIPQSAPWGY
VAAMMVGLIPIVRRAAKGVARGYPFSIETLMTIAAIGAIVIDAAEEAAVVIILFLVGELLEGIAADRARASIRELATLVP
KDALLDEGDGKTRKVPAEELAVDAIVVVRPGDRVPADGVIVEGESAIDEAPVTGESVPKRKTVDDQVFAGTINQEGVLRI
KVTAAAENNTISRVIKLVEDAQEAKAPTERFIDGFSKYYTPGVIVFAFLVTVIPPLAFGGDWSEWLYKGLAVLLIGCPCA
LVISTPAAIAAALSAGAKRGLLMKGGAVLETFRKVTYVAMDKTGTLTEGKPKLTDIHGNGMDEGEVLRIAATLEAGSSHP
LATAILNEAKARNIDHGTAESSKAVAGKGVAGTVDGKSVRLYSPKATEDYMPLGGNMRQSIQRLNDEGKTVSVLIVDDEI
AGFIAMRDEPREDAKAGVWALQRQGITTLMLTGDNKRTGEAIASQLGMQARTELMPEEKQMIVKDLQDQGEVVAKVGDGI
NDAPALAAADVGIAMGGGTDVALETADAAVLHGRVMDIADMIGLSRLTMTNIYQNITIALGLKAVFLVTTVLGITGLWPA
ILADTGATVFVTANAMRLLGWKGGRDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-99 44
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-98 44
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-98 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Astex_3852 YP_004089610.1 cadmium-translocating P-type ATPase BAC0461 Protein 1e-104 48