Gene Information

Name : Astex_3827 (Astex_3827)
Accession : YP_004089587.1
Strain :
Genome accession: NC_014819
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 124868 - 127072 bp
Length : 2205 bp
Strand : +
Note : KEGG: oan:Oant_3208 heavy metal translocating P-type ATPase; TIGRFAM: cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein;

DNA sequence :
ATGGCGTCTCCCTCCCCCATCCGTCTACGCGTCGAAGGCATGGACTGCGGCGCGTGCGCGCTCAAAATTGAAACCGCGGT
CAATCGACTGCCGGGCGCCAGCGATGTCGCCGTGTCCTACCAGAACGAGACGCTCGTTCTCAGTCTGGATGAGGACCTGA
CCCCTGCGGCGAAGCTCCAAGACCAGATTCGCAGCCTCGGATATGTACCGTCCGCACTGGCCGAAGAGACGCGTACGCTT
CCAGCGGTAAAGAGCGCCGTGCCCTGGTGGAAAACCGGTAAGGGCAAACTGGTTTTGATGACCGGTCTGATGTTGGCCAT
CGGGCTGGGATTGGAACGCCTGCTCCCCTCCTACGCGCTCTACATCACCTCCATCGCCGCCCTGATCAGCGTGTTTCCGT
TCGCACGCCGTGCGGTTTCGGGCGCGCTGGCCGGCTCACCCTTCTCCATCGAAACCCTGATGTCGGTGGCCGCCATCGGT
GCGGTCTTAATCGGTGAAGGCGAAGAGGCCCTGACGGTCGTCTTCCTGTTTGCCGTCGGTGAGGTTCTTGAAACCGTTGC
CGCAGGGCGTGCTCGCGCGGGTATCGAGGCCCTGATCGGTCTGGTTCCTCGCACCGCCCGTGTCGAACGCGATAGCGGCG
TCGAAGAAATCCAGGCGGACGCTTTGGAAATAGGCGATATCGCCATCGTCCGGCCCGGCGATCGTATCCCCTCGGACGGA
GAGGTGGTTGAAGGTGAAAGCGAGGTCGACGAATCGCCCGTGACCGGCGAATCTGTGCCCGTGTTCAAGGGATCGGGCGC
AGACGTGTTTGCGGGCAGTATCAACGCTAATGGTACCCTGCGGGTGCGTATCACCCATAAGGCCGCCGACAACACCATTG
CCCGCATCATCCACCTTGTCGAAGAGGCGCAGGAGAGTAAGGCGCCCACGGCACGCTTCATCGACAGGTTCAGCCTGTGG
TACACACCGGCCGCCATGCTGGTGGCCGCCCTGATCATCGTCATTCCGCCCGTGCTCTTTGCTCAGGACTGGACGACGTG
GATTTATCGGGGACTGGCGACCTTGCTCATTGCGTGTCCTTGCGCGTTGGTCATCTCAACCCCGACAGCGATTGCCTCGG
GTCTGGCCGCCGGGGCGCGGCAAGGTCTGCTGATCAAGGGCGGCGCGGCACTGGAAACGCTGGGCAAGATCAAGGCGGTC
GCGTTCGACAAGACCGGCACACTGACGCGCGGCAAGCCGCAGGTGACGGACATCATAGCCCTGACGGGTATGGTGGATGA
CTTTCTGGTGCGCGCCGCTGCCGTCGAAGCCAATACCAGTCACCCACTGGGCAAGGCCATTGTTGACGCCGCGCGCACCC
GCGGGCTGGACATTCCCGCCGCCATTGGGGGTTCTACGGCCGTACCGGGCAAGGCGGTGACGGCGCGACTGAAGTCAGGT
TTTGTCTCGGTCGGCTCCCCATCCTTTGCAGCTAGCAAGGCCGCGCTATCAGAAGAAACGACGGCCAGGATCAATGCCCT
TGAGAAGGAAGGCAAGACCGTCGTGGTCGTCCTCAGCAGCAAGGTCGCCGAAGGGCTGATCGCCATACGCGATGAGTTGC
GCGAGGACGCGAAATCCGCCGTCGCGGCCCTGAACGCGCGGGGAATACAGACACTGATGCTGACCGGCGACAATCGCCGG
ACGGCCGCCGCCATCGCGGCGCAGGTCGGCGTCGAGGCTGAGGCCGAGCTGCTGCCAGAGGCTAAACTCGCGCGGATTGC
GCAGATCGCTACGGATAGCCCAATTGCCATGGTCGGTGATGGGATCAATGACGCGCCGGCTCTCGCGGCGGCCTCGGTCG
GCATCGCCATGGGCGGCGGAACCGATGTCGCGCTTGAAACCGCCGACGCTGCACTGCTGAAGGATCGCGTCACAGGCGTT
CCCCAGCTCATTTCCCTGTCCAGGGCAACGCTGGGCAACATCTGGCAGAACATCGCCCTGGCTCTCGGTCTGAAAGCGGT
CTTCCTCGTTACGACCCTGACCGGTACGACGACCCTATGGATGGCGATCCTCGCCGACACCGGTGCGACCGTGCTGGTGA
CGCTGAACGCCCTGCGCCTTCTGGGGTTCGGGCGCCGAAAAGGCCACAAAGACAAACTGTGCGGCATAATGGACGCAGCA
GAAAATCTGCTCGCGATCAAAACCGAGCTCAAAGCCCGGCGTTAG

Protein sequence :
MASPSPIRLRVEGMDCGACALKIETAVNRLPGASDVAVSYQNETLVLSLDEDLTPAAKLQDQIRSLGYVPSALAEETRTL
PAVKSAVPWWKTGKGKLVLMTGLMLAIGLGLERLLPSYALYITSIAALISVFPFARRAVSGALAGSPFSIETLMSVAAIG
AVLIGEGEEALTVVFLFAVGEVLETVAAGRARAGIEALIGLVPRTARVERDSGVEEIQADALEIGDIAIVRPGDRIPSDG
EVVEGESEVDESPVTGESVPVFKGSGADVFAGSINANGTLRVRITHKAADNTIARIIHLVEEAQESKAPTARFIDRFSLW
YTPAAMLVAALIIVIPPVLFAQDWTTWIYRGLATLLIACPCALVISTPTAIASGLAAGARQGLLIKGGAALETLGKIKAV
AFDKTGTLTRGKPQVTDIIALTGMVDDFLVRAAAVEANTSHPLGKAIVDAARTRGLDIPAAIGGSTAVPGKAVTARLKSG
FVSVGSPSFAASKAALSEETTARINALEKEGKTVVVVLSSKVAEGLIAIRDELREDAKSAVAALNARGIQTLMLTGDNRR
TAAAIAAQVGVEAEAELLPEAKLARIAQIATDSPIAMVGDGINDAPALAAASVGIAMGGGTDVALETADAALLKDRVTGV
PQLISLSRATLGNIWQNIALALGLKAVFLVTTLTGTTTLWMAILADTGATVLVTLNALRLLGFGRRKGHKDKLCGIMDAA
ENLLAIKTELKARR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-98 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-98 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Astex_3827 YP_004089587.1 cadmium-translocating P-type ATPase BAC0461 Protein 1e-107 49
Astex_3827 YP_004089587.1 cadmium-translocating P-type ATPase BAC0298 Protein 4e-85 48
Astex_3827 YP_004089587.1 cadmium-translocating P-type ATPase BAC0100 Protein 9e-54 41