Gene Information

Name : Astex_2656 (Astex_2656)
Accession : YP_004088452.1
Strain :
Genome accession: NC_014817
Putative virulence/resistance : Unknown
Product : gmp synthase, large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 311863 - 313413 bp
Length : 1551 bp
Strand : +
Note : KEGG: GMP synthase large subunit; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I

DNA sequence :
ATGTCGCATCACGAAAAAGTCCTGATTATTGATTTCGGATCGCAAGTGACCCAGCTCATCGCGCGGCGCGTGCGCGAATG
CGGCGTCTATTGCGAAATCCACCCCTTCACCAAGGCCGCTGAGGCGATCAAAAGTGTGGCCCCCAATGCGGTCATCCTGT
CCGGGTCGCCGCACAGCGTCGTCGAAGCCGGTCCGACCGTTGATAAAGCCCTGTTTGATATGGGCCTCCCGGTATTCGGC
ATTTGCTATGGCGAGCAACTGATGTGCGACCTTCTGGGGGGGAAGGTCGAAAGCGGGCATGACCGCGAATTTGGCCGCGC
CGAAATCGAAATCGCCGCCGACACGCCGCTGTTCCGCGGACTGGGCAAGCCGGGCGACAAGGAGATCGTGTGGATGAGCC
ACGGCGACCGCGTTACCGCCATCCCCGAACGCTTCAAGGTCATTGCCGTCTCCGAAGGCGCGCCCTTCGCGGCCATTGCC
GATGAGGCCCGCCGTTTTTACGCCGTGCAGTTCCACCCCGAAGTGGTGCACACGGTGCGCGGCACTCAGATGATCCGCAA
CTTCCTGTTTGAGGTCGCGGGACTTAAGGGCGACTGGACCATGGCCGCCTTCCGTCAGGAGATGATCGAAAAGATCCGGG
CTCAGGTCGGGTCAGGTCGCGTCATCTGCGGTCTGTCGGGTGGGGTGGACTCGTCGGTCGCCGCCGTGCTGATCCACGAA
GCCATCGGCGAGCAACTGACTTGTGTGTTTGTCGATACGGGCCTGCTGCGCAAGAACGAAGGCGAGCAGGTGGTGTCGCT
GTTCCGCGATCACTACAACATCCCGCTGATCCATGTGCAGGCACAGGACAAGTTTCTGGGCGCGCTCAAGGGCCTGTCCG
ACCCGGAACAGAAGCGCAAGACCATCGGCCGCCTGTTTATCGAGGTCTTCGACGAAGAGGCCGCCAAAATCGACGGCGCG
GAATTCCTCGCTCAGGGCACGCTTTATCCCGACGTGGTCGAAAGCGTCTCGCCGCACGGCGGGCCTTCGACCGTCATCAA
GAGCCACCACAATGTCGGCGGTCTGCCCGACTATATGAAGCTGAAGCTGGTCGAACCCTTACGCGAACTGTTCAAGGACG
AGGTGCGCGCTCTGGGCCGCGAACTGGGCCTCAGCGAAGCCTTTGTTGGCCGCCACCCGTTCCCCGGACCGGGTCTGGCT
ATCCGCATCCCCGGCGAAGTGACGCCGGAAAAGGTCAGGACGCTTCAGGACGCCGACGCCATCTATCTCGATGAAATCCG
CAAGGCCGGCCTCTACAACGATATCTGGCAGGCCTTTGCCGTGCTGCTGCCGGTGAAAACCGTAGGCGTAATGGGCGATG
CGCGCACCTATGAGGACGTGCTGGCCCTGCGCGCGGTGACCTCTTCGGACGGCATGACGGCGGACTTCTATGAGTTCCCG
TGGCCGGTGCTGGGCCGCTGCGCCACCCGCATCGTCAATGAGGTGAGGGGGGTGAATCGCGTCGTTTACGACGTGACGTC
AAAGCCCCCCGGCACGATCGAGTGGGAATAA

Protein sequence :
MSHHEKVLIIDFGSQVTQLIARRVRECGVYCEIHPFTKAAEAIKSVAPNAVILSGSPHSVVEAGPTVDKALFDMGLPVFG
ICYGEQLMCDLLGGKVESGHDREFGRAEIEIAADTPLFRGLGKPGDKEIVWMSHGDRVTAIPERFKVIAVSEGAPFAAIA
DEARRFYAVQFHPEVVHTVRGTQMIRNFLFEVAGLKGDWTMAAFRQEMIEKIRAQVGSGRVICGLSGGVDSSVAAVLIHE
AIGEQLTCVFVDTGLLRKNEGEQVVSLFRDHYNIPLIHVQAQDKFLGALKGLSDPEQKRKTIGRLFIEVFDEEAAKIDGA
EFLAQGTLYPDVVESVSPHGGPSTVIKSHHNVGGLPDYMKLKLVEPLRELFKDEVRALGRELGLSEAFVGRHPFPGPGLA
IRIPGEVTPEKVRTLQDADAIYLDEIRKAGLYNDIWQAFAVLLPVKTVGVMGDARTYEDVLALRAVTSSDGMTADFYEFP
WPVLGRCATRIVNEVRGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-137 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-138 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-138 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-123 53