Gene Information

Name : ML5_6006 (ML5_6006)
Accession : YP_004085602.1
Strain : Micromonospora sp. L5
Genome accession: NC_014815
Putative virulence/resistance : Unknown
Product : type i restriction-modification system, m subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 6672449 - 6674017 bp
Length : 1569 bp
Strand : -
Note : TIGRFAM: type I restriction-modification system, M subunit; KEGG: jde:Jden_1499 type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase

DNA sequence :
ATGGCTCCGACGACCAAGGAAGCTCAGCGCGCCGAGCTTCACAAGACGATCTGGCGCATTGCCAACGACCTGCGTGGCTC
TGTCGACGGCTGGGACTTCAAGACCTACGTCCTGGGCATCCTCTTCTACCGGTTCATCTCCGAGAACCTCACCGCTTACG
TCAACGAAGGCGAACGCAGGGCCGGCGAGGCTGACTTCGATTACACCAAGCTGACCGACAAGCAGGCCGAGGTCGGTCGC
AAGGCGACGGTGGCCGAGAAGGGCTTCTACATCCTGCCGAGCGAGCTCTTCGTGAACGTCCGCAAGCGCGCGGCCAGTGA
CCCGGACCTCAACGAGACCCTTGAGAGGGTGTTCCGCAACATCGAGGGATCGGCCGTCGGTACCGACTCCGAGGACGACC
TCAAAGGTCTGTTCGACGACCTCGACGTCAACAGCGGCAAGCTCGGAAACACCGTCGCCAGGCGTAACGAGAAGCTCGTG
AAGCTGCTCAACGCTGTCGGTGACCTCAAGCTGGGCGACTTCAACAACCACGCCATCGACGCCTTCGGCGACGCGTACGA
GTACCTCATGACCATGTACGCCTCAAGCGCCGGCAAGTCCGGCGGCGAGTTCTTCACGCCGCAGGAAGTCAGTGAGCTAC
TGGCGCGCATCACGGTCGTGGGCAAGAAGTCGGTCAACAAGGTCTACGACCCGGCCTGTGGCTCCGGCTCGCTGCTGCTC
CAGTTCGCCAAGGTGTTGGGCCAGAAGAACGTCCGCCAAGGCTTCTTCGGTCAGGAGATTAACCTGACCACCTACAACTT
GGCGCGGATTAACATGTTCCTGCACGACATCGGCTACGAGCAGTTCAACATCGCCCACGGCGACACCCTCCTCGATCCGG
CCCACTGGGACGAGGAACCCTTCGAGGCAATCGTTTCCAATCCGCCGTACTCCACCAAGTGGCCCGGCGACAGCAACCCA
CTACTCATCAACGACCCTCGGTTCTCTCCGGCCGGCGTCCTAGCACCGAAAAGCAAGGCTGACCTTGCCTTCACGATGCA
CATGCTCAGGTGGCTGGCAGTGAACGGCACGGCCGCCATCGTTGAGTTCCCAGGTGTGCTCTACCGAGGCGGTGCCGAGC
AGAAGATCCGTAAGTACCTGGTCGACAACAACTACGTTGATACGGTGATCCAGCTGCCGCCGGACCTCTTCTTCGGCGTC
ACCATTGCGACGTGCATTATCGTGCTGAAAAAATCAAAGAACGATAACAACGTTCTGTTCATCGACGCGTCCGCCGAGTT
TAAGCGCGTCGGCAACAAAAACAAGCTTCTGCCCGAGCATCGGAAGATGATTCTCGACGCCTTTGTTGCTCGGAGGAGCG
TCGATCACTTCGCGCGGCTCGTTCCGAACACGGATATCGCGGGCAACAGCCACAACCTCTCCGTGTCGTCGTACGTCGAG
GAAGAGGACACGCGTCAAAGAGTCGACATCACGGCGCTGAACGCTAAGATCTCGCAGATTGTCGCTCGACAGGATGAGCT
CCGCAAGCAGATCGACGACATCGTGGCCGACCTGGAGAGCGCGCCGTGA

Protein sequence :
MAPTTKEAQRAELHKTIWRIANDLRGSVDGWDFKTYVLGILFYRFISENLTAYVNEGERRAGEADFDYTKLTDKQAEVGR
KATVAEKGFYILPSELFVNVRKRAASDPDLNETLERVFRNIEGSAVGTDSEDDLKGLFDDLDVNSGKLGNTVARRNEKLV
KLLNAVGDLKLGDFNNHAIDAFGDAYEYLMTMYASSAGKSGGEFFTPQEVSELLARITVVGKKSVNKVYDPACGSGSLLL
QFAKVLGQKNVRQGFFGQEINLTTYNLARINMFLHDIGYEQFNIAHGDTLLDPAHWDEEPFEAIVSNPPYSTKWPGDSNP
LLINDPRFSPAGVLAPKSKADLAFTMHMLRWLAVNGTAAIVEFPGVLYRGGAEQKIRKYLVDNNYVDTVIQLPPDLFFGV
TIATCIIVLKKSKNDNNVLFIDASAEFKRVGNKNKLLPEHRKMILDAFVARRSVDHFARLVPNTDIAGNSHNLSVSSYVE
EEDTRQRVDITALNAKISQIVARQDELRKQIDDIVADLESAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 6e-98 43
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 8e-95 42
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 4e-95 42
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 6e-95 42
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 5e-95 42
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 1e-94 42
ORF6 BAC22943.1 - Not tested etd PI Protein 2e-94 42
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 5e-95 42
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 9e-95 42
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 5e-95 42
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 9e-95 42
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 8e-95 42
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 8e-95 42
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 8e-95 42
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 2e-94 42
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 4e-95 42
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 5e-95 42
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 4e-95 42
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 2e-94 41
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 2e-94 41
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 5e-95 41
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 6e-94 41