Gene Information

Name : ML5_5496 (ML5_5496)
Accession : YP_004085108.1
Strain : Micromonospora sp. L5
Genome accession: NC_014815
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5920755 - 5923304 bp
Length : 2550 bp
Strand : -
Note : KEGG: saq:Sare_2308 ATPase; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase

DNA sequence :
ATGATGGGACCGGGTGACTTCGGCAACGACCCCTGGGACGAGTTCCTGGCCCGATACTTCGGCCGGGGCGAGGGGGGACG
CCGGCCGGCGCACCGGGTCGACATCACGCGCCTGATGACCGCCGACGCCCGGGAGATGCTCGCCGACGCGGCCCGCCGCG
CCGCCCAGAAGCACAGCAACGACCTGGACACCGACCACCTGCTCTGGGCGGCGTTGCAGCGCGAGCCGTTGCGTGACCTG
GTCCGCCGGGCCGGCGCCGACCCGGACGCGCTGCTGGGCGCGCTGGGCGGGCGCGGTGAGGGCGCACCGCGCGGCGAGGT
GCCGCCGAACCTGTCGCTGACCCCGGCCGCGAAGCGGGCGCTGCTGGACGCGCACCAGCTGTCCCGCGCCATGGGCGCCA
ACTACATCGGTCCCGAGCACATCCTGATGGCGTTGCCGCTGAACCCCGAGTCGCCGGCCGGCCGGATGCTCGCCGCCGGC
CGGATCCAGCCCGAGTCGTTGCAGGCGGCCAGCGCCGAGCGCGGCGCGGCGAACGCCCCGCGCCCGGACCGGGGCACCCC
GACGCTCGACCAGTACGGCCAGGACCTCACCGAGCTGGCCCGGATGGACCAGATCGACCCGGTGATCGGCCGGGCCGACG
AGATCGAGCAGGCGGTGGAGATCCTGTCCCGGCGGACCAAGAACAACCCGGTGCTGATCGGTGAGGCCGGTGTCGGCAAG
ACCGCGATCGTGGAGGGCCTGGCCGAGCGGATCTGTGACGGCGACGTGCCGCAGACGCTGATCGGCAAGCGGGTGATCCA
GCTCGACCTGTCCGGCCTGGTCGCCGGCACCCGCTACCGGGGTGACTTCGAGGAGCGCCTGAAGAAGGTGATCGACGAGA
TCCGCGCCCACCGCGAGGAGCTGATCATCTTCCTGGACGAGATCCACACGCTGGTCGGCGCGGGCGGCGCCGGCAGCGAG
GGCGGAATGGACGCGTCGAACATGCTCAAGCCCGCCCTGGCGCGCGGCGAGCTGCGGGTGATCGGCGCGACCACGCTCGA
CGAGTACCGGCGCAGCATCGAGAAGGACGCCGCACTGGCCCGCCGGTTCCAGCCGGTGCTGGTGCCCGAGCCGACGGTCG
ACGACACCATCGCGATCCTGCGCGGCCTGCGCGACCGGTACGAGGCGCACCACCAGGTCCGGTTCACCGACGAGGCGCTG
ATCGCCGCCGGTGAGCTGTCCGACCGGTACGTCACCGACCGGTTCCTGCCGGACAAGGCGATCGACCTGATCGACCAGGC
CGGCGCGCGGGTGCGGCTGCGCACCCGTACCCCCGCCGAGGACGTGCGCGAGCTGGAGCAGCAGCTCGACGAGACGCGCC
GGGACAAGGAACAGGCGGTCTCCGACGAGCAGTACGAGCGGGCCTCCGCGCTGCGCGACCGGCTAGCCGAACTGGAGGAC
CAGGTCCGCCGCGCCCGCGGCGACGAGGGCCCCAGCCACGTGCCCGAGGTGGGGCCGACGGAGATCGCCGAGGTGGTCTC
CCGGGCCACCGGCATCCCGGTCACCCAGCTCACCGAGGAGGAACGCGACCGGCTGCTGCGCCTGGAGGGGCACCTGCACG
AGAAGATCATCGGCCAGGACGACGCGGTCAGCGCCGTCGCCGAGGCGGTACGCCGCTCCCGCACCGGGCTGGCCGACCCG
GACCGGCCGATGGGCAGCTTCCTGTTCCTCGGCCCGACCGGCGTCGGCAAGACCGAGCTGGCCCGCGCGCTCGCCGAGGC
GCTGTTCGGCGAGGCGGACCGGATGGTCCGGGTGGACATGAGCGAGTTCCAGGAACGGCACACGGTCAGCCGGCTGGTCG
GCGCCCCGCCCGGGTACGTCGGCTACGAGGAGGCCGGTCAGCTCACCGAGGCGGTCCGCCGCCGCCCGTACGCGGTGGTG
CTGCTCGACGAGATCGAGAAGGCGCACCCGGACGTGTTCAACATCCTGCTCCAGGTGCTCGACGACGGCCGGCTCACCGA
CAGCCAGGGCCGCACCGTGAACTTCAAGAACACCGTCCTGATCATGACCAGCAACCTCGGCTCGGAGCTGATCACCGGCA
CCCAGCGCACCGTCGGCTTCGCCACCGGCGGGCCCGGCGAGCAGGAGAGCGACGAGCTGCGGGAGCGGCTGATGCGCCGG
CTCCAGGAGAACTTCCGCCCGGAGTTCCTCAACCGCATCGACGAGGTGATCATCTTTCAGCGGCTGGAGGCCGAGCAGCT
CCGCCAGATCACCGGGCTGCTGCTGGAGGAGACCCGCCGCCGCATGCACGCCCAGGACATCCAGGTCGACTTCAGTACGG
CGGGCGTCGACTGGCTCGCCGAGCACGGCTACCAGCCGGAGTTCGGCGCCCGGCCGCTGCGCCGGGTGATCCAGCGCGAG
GTCGACAACCGGCTGTCCCGGATGCTGCTGGAGAACAAGGTCTCACCGGGGCAGAAGGTCACCGTCGACACCCGTGACGA
CCAGCTCGTCTTCGACGTCACCGCCGGTGAGCGGGGCTACACACCGGCCACCACGTCCCATCCCCGATGA

Protein sequence :
MMGPGDFGNDPWDEFLARYFGRGEGGRRPAHRVDITRLMTADAREMLADAARRAAQKHSNDLDTDHLLWAALQREPLRDL
VRRAGADPDALLGALGGRGEGAPRGEVPPNLSLTPAAKRALLDAHQLSRAMGANYIGPEHILMALPLNPESPAGRMLAAG
RIQPESLQAASAERGAANAPRPDRGTPTLDQYGQDLTELARMDQIDPVIGRADEIEQAVEILSRRTKNNPVLIGEAGVGK
TAIVEGLAERICDGDVPQTLIGKRVIQLDLSGLVAGTRYRGDFEERLKKVIDEIRAHREELIIFLDEIHTLVGAGGAGSE
GGMDASNMLKPALARGELRVIGATTLDEYRRSIEKDAALARRFQPVLVPEPTVDDTIAILRGLRDRYEAHHQVRFTDEAL
IAAGELSDRYVTDRFLPDKAIDLIDQAGARVRLRTRTPAEDVRELEQQLDETRRDKEQAVSDEQYERASALRDRLAELED
QVRRARGDEGPSHVPEVGPTEIAEVVSRATGIPVTQLTEEERDRLLRLEGHLHEKIIGQDDAVSAVAEAVRRSRTGLADP
DRPMGSFLFLGPTGVGKTELARALAEALFGEADRMVRVDMSEFQERHTVSRLVGAPPGYVGYEEAGQLTEAVRRRPYAVV
LLDEIEKAHPDVFNILLQVLDDGRLTDSQGRTVNFKNTVLIMTSNLGSELITGTQRTVGFATGGPGEQESDELRERLMRR
LQENFRPEFLNRIDEVIIFQRLEAEQLRQITGLLLEETRRRMHAQDIQVDFSTAGVDWLAEHGYQPEFGARPLRRVIQRE
VDNRLSRMLLENKVSPGQKVTVDTRDDQLVFDVTAGERGYTPATTSHPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-164 51
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ML5_5496 YP_004085108.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 7e-177 54
ML5_5496 YP_004085108.1 ATPase AAA-2 domain-containing protein VFG0080 Protein 2e-145 50