Gene Information

Name : ML5_3902 (ML5_3902)
Accession : YP_004083564.1
Strain : Micromonospora sp. L5
Genome accession: NC_014815
Putative virulence/resistance : Unknown
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 4113151 - 4114599 bp
Length : 1449 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; KEGG: saq:Sare_3385 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
ATGGGCGTGACACGCCGCGCGAAGATCGTCTGCACTCTCGGCCCCGCAACCGCCTCCCCGGAGCGTATCCGCGGGCTCGT
AGAAGCCGGCATGAACGTGGCGAGGCTCAACTTCAGCCACGGCAGTCACGCCGACCACGAATCGGTCTACCGGTTGGTCC
GGGAGGCCGCCGAGGCGTCCGGGCGCCCGGTCGCCGTGCTCGCCGACCTCCAGGGGCCCAAGATCCGGCTGGGCCGGTTC
GCCGACGGCCCGCACGAGTGGCGCACCGGCGACTCCGTCGTGATCACCGGCGACGAGGTGGTGGGCACCAAGGAGCGGGT
CTCCTGCACCTACCGCAAGCTGCCGCAGGAGGTGAAGCCGGGCGACCGGCTGCTGATCGACGACGGCCGGGTCGCGGTCG
AGGTCAGCGACGTCACCGGCAACGACATCCGGTGCCTGGTCACCGAGGGCGGCCCGGTCTCCAACAACAAGGGCGTCTCG
CTGCCGAACGTCGCGGTGAGCGTCCCGGCCCTGTCCGACAAGGACGCCGAGGACCTGCGCTTCGCCCTCGGCCTCGGCGT
CGACCTGGTCGCGCTCTCCTTCGTCCGCTCGCCGGAGGACATCAAGCTCGTCCACTCGATCATGGACGAGGAGGGCGTGC
GCCGCCCGGTCCTGGCCAAGGTCGAGAAGCCGGAGGCGGTCGACCACCTGGAGGCGATCGTGCTCTCCTTCGACGGGGTC
ATGGTCGCCCGCGGCGACCTCGGCGTCGAACTGCCGCTGGACCAGGTGCCGCTGGTGCAGAAGCGTGCCGTGCAGCTGTG
CCGGGAGAACGCCAAGCCGGTCATCGTGGCCACCCAGATGCTCGACTCGATGATCGAGAACTCCCGCCCGACCCGCGCCG
AGGCCTCCGACGTGGCCAACGCGGTGCTCGACGGCGCGGACGCGGTGATGCTCTCCGGCGAGACGAGCGTCGGCAAGTAC
CCGGTGCTCACCGTCAGCACCATGGCGAAGATCATCACCACCACCGAGGCCGGCTCGATCGCCGTCCCCCGGTTGCAGCA
CGACCCGCGTACGCACGGCGGCGCGCTCACGGTCGCCGCCTCGTCGATCGCCCGGGCCATCGGCGCCAAGGCCATGGTCG
CGTTCTCGCAGACCGGTGACACCGTCAAGCGGCTGGCCCGGCTGCACTGCGACCTGCCGCTGCTGGCGTTCACGCCGGTG
CCGGAGGTGCGCAACCAGCTCGCGCTCTCCTGGGGCGTGGAGACGTTCCTGATGCCGTTCGTCGAGCACACCGACGACAT
GTTCCGCCAGGTCGACCAGGCGCTGCTCGGCCTCAACCGGGCCAACCCGGGTGACTACGTGGTGATCGTGGCGGGCAGCC
CGCCCGGCACCCCCGGCTCCACCAACACGCTGCGCGTGCACCAGCTCGGTTCGCTGGTCGACGCGGCCTCGGCCCGGGCG
CTCCAGTGA

Protein sequence :
MGVTRRAKIVCTLGPATASPERIRGLVEAGMNVARLNFSHGSHADHESVYRLVREAAEASGRPVAVLADLQGPKIRLGRF
ADGPHEWRTGDSVVITGDEVVGTKERVSCTYRKLPQEVKPGDRLLIDDGRVAVEVSDVTGNDIRCLVTEGGPVSNNKGVS
LPNVAVSVPALSDKDAEDLRFALGLGVDLVALSFVRSPEDIKLVHSIMDEEGVRRPVLAKVEKPEAVDHLEAIVLSFDGV
MVARGDLGVELPLDQVPLVQKRAVQLCRENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKY
PVLTVSTMAKIITTTEAGSIAVPRLQHDPRTHGGALTVAASSIARAIGAKAMVAFSQTGDTVKRLARLHCDLPLLAFTPV
PEVRNQLALSWGVETFLMPFVEHTDDMFRQVDQALLGLNRANPGDYVVIVAGSPPGTPGSTNTLRVHQLGSLVDAASARA
LQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-71 41
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-67 41