Gene Information

Name : ML5_3776 (ML5_3776)
Accession : YP_004083438.1
Strain : Micromonospora sp. L5
Genome accession: NC_014815
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 3971972 - 3973690 bp
Length : 1719 bp
Strand : +
Note : TIGRFAM: urease, alpha subunit; KEGG: ypb:YPTS_3058 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein

DNA sequence :
ATGAGTCAGATCTCACGGCAGGAATATGCCGGAATGTACGGCCCGACCACGGGCGACCAGATCCGTCTGGGTGACACCGA
CCTCTACATCGAGATCGAGAAGGACCTGCGGGTCCTCGGCGACGAGGTCATGTACGGCGGTGGCAAGACCCTGCGCGACG
GCATGGGCAGTGCCAGCCAGGCCACGAGCGCCGAGGGCGTGGTGGACCTGGTGATCACCAACGTGACCGTCGTGGACGCG
CTGCTCGGCGTGGTCAAGGCGGACGTGGGGATCAAGGACGGCAGGATCGCCGGGATCGGCAAGGCCGGCAACCCCAACAT
CATGGACGGGGTGACCCCGGGCCTGGTGACCGGTCCGGGCACCGACGCGATCTCCGGTGAGCACCTGATCCTGACCGCCG
GCGGCATCGACGCGCACGTCCACCTGGTCACCCCGCAGCAGGTGTACGCCGCGCTCAGCAACGGCGTCACCACCCTCTGG
GGCGGCGGCACCGGACCGACCGACAGCACCAACGGCGTCACCATCACGCCCGGTCCCTGGAACATCCACAACATGATGCG
GTCGTTCGAGAACCTGCCGATCAACATCGGCCTGCTGGGCAAGGGCAACAGCAGTGGCCGGGCGCCGCTCGTCGAGCAGA
TCATGGCCGGGGTGCCCAGCTTCAAGATCCACGAGGACTGGGGTGCGCCGCCCGCGGTGATCCGGTCCTGCCTGGCCGTC
GCCGACGAGTACGACGTCCAGATCAGCATCCACACCGACACGCTCAACGAGAGCGGCTACATCGAGGACAGCATCGCCGC
CTTCGAGGGCCGGACCATCCACACCTTCCACACCGAGGGTGCCGGCGGCGGGCACGCGCCGGACATCATCAAGGTCGCCG
GCCAGATGAACGTGCTGCCCGCCTCGACCACGCCGACGGTGCCGTACGGCATCAACAGCCAGTCCGAGCTGTACGACATG
ATCATGGTCTGCCACAACTTCAACCCGAAGGTGCCCTCGGACGTCGCCTTCGTGGAGAGCCGGATCCGCACCGAGACCAT
CGCCGCCGAGGACGTGCTCCTCGACGAGGGCGTCATCTCGATGATGCAGAGCGACTCGCAGGCCATGGGCCGGGTGGGGG
AGACCTGGCTGCGCACCGTCCAGCTCGCCGGGCAGATGAAGAACGTCCGCGGCAAGCTGGCCGAGGACTCCGACGCCAAC
GACAACTTCCGCGTCCTGCGCTACGTCGCCAAGATGACCATCAACCCGGCGATCACCCAGGGCGTCTCGCACGTCATCGG
CTCGGTCAGCCCGGGCAAGCTCGCCGACCTGGTGCTCTGGGAGCCCGCGTTCTTCGGCACGAAGCCGAAGATGGTGCTCA
AGGGCGGCATGATCGCCTGGTCGATCATGGGCGACCCGAACGCGTCGCTGCCCACCCCGCAGCCGGTCTACTACCGGCCC
ATGTTCGGCGCCACCGGCTCCCAGGTCGCCAAGAACTGCGTGACGTTCGTGTCCCGGGCCGCGCACGAGGCGGGCGTGGC
CGAACAGCTGGGTCTGCAACGGCAGGTCATGCCGGTCTACGGCTGCCGCAACCTGACCAAGCGCGACATGGTGCGCAACG
ACCGTACGCCGAAGCTCGAAGTCGACCCGGAGACCTTCGCCGTGAAGATGGACGGCGTGCACGCGACAGTGCCGGCGGCC
AAGAACCTCCCCCTCAGCCAGCTCTACTTCTTCAGCTGA

Protein sequence :
MSQISRQEYAGMYGPTTGDQIRLGDTDLYIEIEKDLRVLGDEVMYGGGKTLRDGMGSASQATSAEGVVDLVITNVTVVDA
LLGVVKADVGIKDGRIAGIGKAGNPNIMDGVTPGLVTGPGTDAISGEHLILTAGGIDAHVHLVTPQQVYAALSNGVTTLW
GGGTGPTDSTNGVTITPGPWNIHNMMRSFENLPINIGLLGKGNSSGRAPLVEQIMAGVPSFKIHEDWGAPPAVIRSCLAV
ADEYDVQISIHTDTLNESGYIEDSIAAFEGRTIHTFHTEGAGGGHAPDIIKVAGQMNVLPASTTPTVPYGINSQSELYDM
IMVCHNFNPKVPSDVAFVESRIRTETIAAEDVLLDEGVISMMQSDSQAMGRVGETWLRTVQLAGQMKNVRGKLAEDSDAN
DNFRVLRYVAKMTINPAITQGVSHVIGSVSPGKLADLVLWEPAFFGTKPKMVLKGGMIAWSIMGDPNASLPTPQPVYYRP
MFGATGSQVAKNCVTFVSRAAHEAGVAEQLGLQRQVMPVYGCRNLTKRDMVRNDRTPKLEVDPETFAVKMDGVHATVPAA
KNLPLSQLYFFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-143 56
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-143 56
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-132 55
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-132 55
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-132 55
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-132 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ML5_3776 YP_004083438.1 urease subunit alpha VFG0270 Protein 3e-144 57