Gene Information

Name : ML5_0149 (ML5_0149)
Accession : YP_004079853.1
Strain : Micromonospora sp. L5
Genome accession: NC_014815
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone clpb
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 149641 - 152232 bp
Length : 2592 bp
Strand : +
Note : TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; KEGG: saq:Sare_0120 ATPase; SMART: AAA ATPase

DNA sequence :
ATGAACACGGAACGTCTCACCACCAAGAGCCGCGAAGCCATCACCGGTGCCGTCGCGCTGGCGAACCAGCGCGGTCACGC
CACCGTGGAGCCCTGGCACCTGCTGCTGTCACTGCTGGACACCGAAGGCTCGACCGCCGCGGGCCTGCTGCGCGCCGTCG
GGGCCGACCCCGCCGAGCTGCGCCGCGTCGCCCAACGCTCGGTCGACGCGCTGCCGGCCGCACGCGGGTCGAGCATCGCC
GAGCCGACCCTGGCCCGCGAGTTCGTCAACGCCATCGGCGCCGCCGAGCAGATCGCGCGGCCGCTGGGCGACGAGTACAC
CTCCACCGAGCACCTGCTGGCCGGGCTGGCCCGGGTCGGCGGCGCGGTCTCGGTCGCGCTGAAGAACTCCGGCGCCACCG
AGGAGAACCTGGTCGCCGCGTTCCCGACCGTCCGTGGCGGCGACCGCCGGGTGACTACCGCCGACCCGGAGCAGACCTAC
CAGGCCCTGGCCAAGTACGGCGTGGACCTCACCGCCAGCGCCCGCGACGGCAAGATCGACCCGGTGATCGGCCGGGACTC
GGAGATCCGCCGGGTGATCCAGGTGCTGTCCCGGCGTACCAAGAACAACCCGGTGCTGATCGGCGAGCCGGGCGTCGGCA
AGACCGCGATCGTGGAGGGCCTGGCCCAGCGGATCGTGGCCGGCGACGTGCCGGAGTCGCTGCGGGACAAGAAGCTCGTC
TCGCTCGACCTCGGCGCGATGGTCGCCGGTGCGTCGTACCGCGGTCAGTTCGAGGAGCGGCTGAAGTCCGTGCTGGAGGA
GATCAAGAACTCCGACGGCCAGGTCATCACGTTCCTGGACGAGCTGCACACCGTGGTCGGTGCCGGCAAGGGCGAGGGCT
CGATGGACGCCGGCAACATGCTCAAGCCGATGCTGGCGCGCGGCGAGCTGCGGATGGTCGGCGCGACCACGCTCGACGAG
TACCGCGAGCACATCGAGAAGGACCCGGCCCTGGAGCGCCGCTTCCAGCCGGTGCTGGTCGGCGAGCCGACCATCGAGGA
CACCATCGGCATCCTGCGCGGGCTCAAGGAGCGCTACGAGGTGCATCACGGCGTACGGATCACCGACGCCGCACTAGTGG
CCGCCGCCTCGCTCTCCGACCGGTACATCACCGACCGGTTCCTGCCGGACAAGGCGATCGACCTGGTGGACGAGTCGGCG
TCCCGGCTGCGCATGGAGATCGACTCGCGCCCGGTCGAGGTGGACGAGATCGAGCGGGCGGTACGCCGCCTGGAGATCGA
GGAGATGGCGCTCGCAAAGGAGCCGGACGCCGCGTCCGCCGAGCGTCTGGAGCGGCTGCGCAAGGAGCTGGCCGACAAGC
GCGAGCAGCTCACCGCGCTCTCCGAGCGCTGGCAGACCGAGAAGAGCCACATCACCAAGCTCTCCACCGCCAAGGAGGAG
CTGGAGCGCCTCGGTGGCGAGGCCGAGCGGGCCGAGCGCGACGGCGAACTGGAACGCGCCGCCGAGCTGCGGTACGGCCG
GATCCCCGCGCTGCGGACCGAGCTGAAGCAGGCCGAGGAGGAGCTGGCCCGGCTCCAGGCCGACGGCGCGATGCTCAAGG
AGGAGGTCGGCGCGGACGACATCGCCGCAGTGGTCGCCTCCTGGACCGGCATCCCCGCCGGGCGGCTGCTCGAAGGCGAG
ACCGCCAAGCTGCTCCGGATGGAGGAAACGCTGCGCGGCCGCGTGGTCGGCCAGGCCGAGGCGGTGGGCGCGGTCTCCGA
CGCGGTACGCCGCGCCCGGGCCGGCGTCGCCGACCCGGACCGGCCGACCGGCAGCTTCCTGTTCCTCGGCCCGACCGGCG
TCGGCAAGACCGAGCTCGCAAAGGCGCTCGCCGAGTTCCTCTTCGACGACGAGCGGGCCATGGTCCGCATCGACATGAGC
GAGTACGGCGAGAAGCACTCGGTGGCCCGCCTGGTCGGCGCCCCGCCCGGGTACGTCGGCTACGAGGAGGGCGGCCAGCT
CACCGAGGCGGTACGCCGCCGGCCGTACTCGGTGATCCTGCTGGACGAGGTGGAGAAGGCCCACCCGGACGTCTTCGACG
TGCTGCTCCAGGTGCTCGACGACGGCCGGCTCACCGACGGTCAGGGCCGTACCGTGGACTTCCGCAACGCGATCCTGATC
CTCACCTCGAACCTCGGTTCGTCGGTGATCAGCGACCTGACGCTCACCGAGAACGAGCGCCGGGAGGGTGTGCTCGCGGT
GGTCCGGTCGCACTTCAAGCCGGAGTTCCTCAACCGGCTCGACGACATCGTGGTGTTCGCCGCGCTCCAGGGCGAGGACC
TGCGGTCGATCGTGGACATCCAGCTCGACCGGATGCGAACCCGTCTTGCGGACCGCCGGTTGGCACTGGACATCAGCGAC
TCCGCACGCAACTGGCTGGCCGAGCACGGGTACGACCCGATCTACGGTGCCCGCCCGCTGCGCCGGTTGGTGCAGTCGGC
GATCGGCGACCAGCTCGCGAAGGCGCTGCTGGCCGGTGACATCCGCGACGGCGACACGGTCCGCGTCGACCTGTCCGACT
CCAAGGAGTCCCTGGCGGTGACCGCCGCCTGA

Protein sequence :
MNTERLTTKSREAITGAVALANQRGHATVEPWHLLLSLLDTEGSTAAGLLRAVGADPAELRRVAQRSVDALPAARGSSIA
EPTLAREFVNAIGAAEQIARPLGDEYTSTEHLLAGLARVGGAVSVALKNSGATEENLVAAFPTVRGGDRRVTTADPEQTY
QALAKYGVDLTASARDGKIDPVIGRDSEIRRVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKKLV
SLDLGAMVAGASYRGQFEERLKSVLEEIKNSDGQVITFLDELHTVVGAGKGEGSMDAGNMLKPMLARGELRMVGATTLDE
YREHIEKDPALERRFQPVLVGEPTIEDTIGILRGLKERYEVHHGVRITDAALVAAASLSDRYITDRFLPDKAIDLVDESA
SRLRMEIDSRPVEVDEIERAVRRLEIEEMALAKEPDAASAERLERLRKELADKREQLTALSERWQTEKSHITKLSTAKEE
LERLGGEAERAERDGELERAAELRYGRIPALRTELKQAEEELARLQADGAMLKEEVGADDIAAVVASWTGIPAGRLLEGE
TAKLLRMEETLRGRVVGQAEAVGAVSDAVRRARAGVADPDRPTGSFLFLGPTGVGKTELAKALAEFLFDDERAMVRIDMS
EYGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVILLDEVEKAHPDVFDVLLQVLDDGRLTDGQGRTVDFRNAILI
LTSNLGSSVISDLTLTENERREGVLAVVRSHFKPEFLNRLDDIVVFAALQGEDLRSIVDIQLDRMRTRLADRRLALDISD
SARNWLAEHGYDPIYGARPLRRLVQSAIGDQLAKALLAGDIRDGDTVRVDLSDSKESLAVTAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-95 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ML5_0149 YP_004079853.1 ATP-dependent chaperone clpb VFG2076 Protein 1e-106 45
ML5_0149 YP_004079853.1 ATP-dependent chaperone clpb VFG2084 Protein 8e-98 44