Gene Information

Name : ML5_1222 (ML5_1222)
Accession : YP_004080912.1
Strain : Micromonospora sp. L5
Genome accession: NC_014815
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1228163 - 1229668 bp
Length : 1506 bp
Strand : -
Note : PFAM: Aldehyde Dehydrogenase; KEGG: saq:Sare_0895 aldehyde dehydrogenase

DNA sequence :
ATGACGCGCTACGACGCCCCCACCCACTGGCAGTCCCGCTACGACCACTACATCGGCGGCGAGTACGTGAAGCCGCACGG
TGGGAAGTACTTCGAGAACCCGACCCCGGTGACCGGGCAGACCTTCTGCGAGGTGGCCCGGGGCACCGCCGAGGACGTGG
AGAAGGCGCTCGACGCGGCGCACGGCGCGGCCGACGCGTGGGGCCGCACGTCGGTCGCCGAACGCTCGCTGATCCTCAAC
CGGATCGCCGACCGCATGCAGGACAACCTGGAGTCCCTCGCGATCGCCGAGACGTGGGAGAACGGCAAGCCCGTACGCGA
GACGCTCGCCGCCGACCTCCCGCTCGCGATCGACCACTTCCGCTACTTCGCCGGCGCGATCCGGGCGCAGGAGGGCTCGC
TCGGCGAACTCGACGACGACACAGTCGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGGCAGATCATCCCGTGGAAC
TTCCCGATCCTCATGGCGGTGTGGAAGCTCGCCCCGGCGCTGGCCGCCGGCAACGCGGTGGTGCTCAAGCCGGCCGAGCA
GACACCCGCCTCGATCCACTACCTGCTCTCGCTGATCGGCGACCTGCTGCCGCCGGGCGTGGTGAACGTGGTGAACGGCT
TCGGCGTCGAGGCGGGCAAGCCGCTGGCGTCCTCGCCGCGGGTGGCGAAGGTGGCGTTCACCGGCGAGACCACCACCGGG
CGGCTGATCATGCAGTACGCCAGCGAGAACATCAGGCCGGTCACGCTGGAGCTGGGCGGCAAGAGCCCGAACATCTTCTT
CGACGACGTCAGCGCCGCCTCCGACGACTTCCTGGACAAGGCCCTGGAAGGCTTCACCATGTTCGCCCTGAACCAGGGCG
AGGTGTGCACCTGCCCGTCGCGGGCGCTCATCCAGCAGGGCCACTATGCCGACTTCCTGGCCGCCGCCGTGGACCGGACC
CGGCAGATCACGCAGGGGCACCCGCTGGACACCGACACGATGGTCGGCGCGCAGGCGTCCAACGACCAGCTGGAGAAGAT
CCTGTCCTACCTGGACATCGGGCGGCAGGAGGGCGCTCGCGTCCTCACCGGCGGTGAGCGGGCGGACCTCGGCGGCGAGT
TGTCCGGCGGCTACTACGTCCAGCCGACCATTTTCGAGGGCGACAACTCGATGCGGATCTTCCAGGAGGAGATCTTCGGC
CCGGTGGTGTCGGTGACCTCCTTCGCCGACCTGGACGACGCCGTGAAGATCGCCAACGACACGCTGTACGGGCTCGGCGC
GGGCGTGTGGACCCGGGACCTGAACACCGCGTACCGGGCCGGACGGGCGATCCAGGCCGGCCGGGTGTGGACGAACTGCT
ACCACGCGTACCCGGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAGAACCACAAGATGATGCTG
GAGCACTACCAGCAGACCAAGAACCTGCTGGTCAGCTACTCGCCGAAGAAGCTGGGCTTCTTCTGA

Protein sequence :
MTRYDAPTHWQSRYDHYIGGEYVKPHGGKYFENPTPVTGQTFCEVARGTAEDVEKALDAAHGAADAWGRTSVAERSLILN
RIADRMQDNLESLAIAETWENGKPVRETLAADLPLAIDHFRYFAGAIRAQEGSLGELDDDTVAYHFHEPLGVVGQIIPWN
FPILMAVWKLAPALAAGNAVVLKPAEQTPASIHYLLSLIGDLLPPGVVNVVNGFGVEAGKPLASSPRVAKVAFTGETTTG
RLIMQYASENIRPVTLELGGKSPNIFFDDVSAASDDFLDKALEGFTMFALNQGEVCTCPSRALIQQGHYADFLAAAVDRT
RQITQGHPLDTDTMVGAQASNDQLEKILSYLDIGRQEGARVLTGGERADLGGELSGGYYVQPTIFEGDNSMRIFQEEIFG
PVVSVTSFADLDDAVKIANDTLYGLGAGVWTRDLNTAYRAGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHKMML
EHYQQTKNLLVSYSPKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-136 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-140 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-140 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-140 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-140 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ML5_1222 YP_004080912.1 aldehyde dehydrogenase VFG0082 Protein 5e-137 62