Gene Information

Name : ML5_1174 (ML5_1174)
Accession : YP_004080864.1
Strain : Micromonospora sp. L5
Genome accession: NC_014815
Putative virulence/resistance : Resistance
Product : cys/met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1172532 - 1173674 bp
Length : 1143 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: saq:Sare_0863 cystathionine gamma-synthase

DNA sequence : 
ATGAGCCACGGCTTCGAGACACTCGCCATCCACGCCGGTCAGGACCCGGAGGCCCGCACCGGTGCGGTGATCCCGCCGAT
CTACCAGACCAGCACGTACGCCCAGGACGCCGTCGGCGCGCCCCGCGAGGGCTACGAGTACAGCCGCTCCGGTAACCCCA
CCCGCGACGCGCTCCAGGAGTGCCTCGCCGCGCTGGAGGGCGGCCCGGTGGCGCTCGCCTTCGCCAGCGGCCTGGCCGCC
GAGGACACGCTGCTGCGGACCGTCTGCAAGCCGGGCGACCATGTGGTGATCCCGGACGACGCGTACGGCGGCACGTACCG
GCTGTTCGCCAAGGTGGCCGAGCGCTGGGGCCTGTCGTACACCCCGGCGAAGGTATCCGACCCGGACGCCGTTCGTGCCG
CGATCCGCCCGGGCACCACCAGGATCGTCTGGGTGGAGACGCCGACCAACCCGCTGCTCGGCATCGCCGACATCGCCGCG
CTCGCCGCGGTGGCGCACGACGCCGGCGCGTTGCTGGTGGTCGACAACACGTTCGCCTCGCCGTACCTCCAGCAGCCGAT
CGCGTTCGGCGCGGACGTGGTGGTGCACTCCACCACCAAGTACGTCGGCGGGCACTCCGACGTGGTCGGCGGCGCGCTCG
TCGCGGCGGACCGCACGCTCGGCGAGGAGCTGCGCTACCACCAGAACGCGATGGGCGCGGTCAACGGGCCGTTCGACGCC
TGGCTCACCCTGCGCGGCATCAAGACCCTCGGGGTACGGATGGACCGGCACTGCGACAACGCCGAGCGGGTCGCGGCCTA
CCTGGACGGACACGCCAAGGTCGCCCAGGTCGTCTACCCGGGCCTGCCCTCGCACCCCGGCCACGAGGTGGCCGCCAAGC
AGATGCGCCGGTTCGGCGGCATGATCTCGTTCCGCGCGGCGGGCGGCGAGGAGCACGCCGTCCAGATCTGCAACCGGGCC
CGGTTGTTCGTGCTCGCCGAGTCGCTCGGCGGCGTCGAGTCCCTGATCGAGCACCCGGGCCGGATGACACACGCAAGCGC
TGCGGGCTCGCCGCTTGAAGTTCCCGGCGATCTCGTGCGACTGTCTGTCGGCATCGAGACGGTCGACGACCTGCTCGCCG
ATCTGGAGCAGGCCCTGGGCTGA

Protein sequence : 
MSHGFETLAIHAGQDPEARTGAVIPPIYQTSTYAQDAVGAPREGYEYSRSGNPTRDALQECLAALEGGPVALAFASGLAA
EDTLLRTVCKPGDHVVIPDDAYGGTYRLFAKVAERWGLSYTPAKVSDPDAVRAAIRPGTTRIVWVETPTNPLLGIADIAA
LAAVAHDAGALLVVDNTFASPYLQQPIAFGADVVVHSTTKYVGGHSDVVGGALVAADRTLGEELRYHQNAMGAVNGPFDA
WLTLRGIKTLGVRMDRHCDNAERVAAYLDGHAKVAQVVYPGLPSHPGHEVAAKQMRRFGGMISFRAAGGEEHAVQICNRA
RLFVLAESLGGVESLIEHPGRMTHASAAGSPLEVPGDLVRLSVGIETVDDLLADLEQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-64 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-65 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-57 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ML5_1174 YP_004080864.1 cys/met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 1e-58 43