Gene Information

Name : Mspyr1_07550 (Mspyr1_07550)
Accession : YP_004075290.1
Strain : Mycobacterium gilvum Spyr1
Genome accession: NC_014814
Putative virulence/resistance : Virulence
Product : response regulator with CheY-like receiver domain and winged-helix DNA-binding domain
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 760879 - 761589 bp
Length : 711 bp
Strand : -
Note : PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal

DNA sequence : 
GTGGTGACCCGAGTCCTCATCGCCGATGACGATGGCGTCGTCCGCGACGTCGTCCGCCGCTACCTGGAGCGCGACGGACT
CGAGGTGTCCACCGCACACGACGGCAACGAGGCGCTGCGACTGCTCAGTTCGCAGCGCATCGACGTCGCAGTGCTCGACG
TGATGATGCCCGGCCCCGACGGGATGGCGCTGTGCCGACGTCTGCGCCAGAACGGCCACTACTCGGTGCCCGTGATCCTG
CTGACGGCCCTCGGCGAGGAGGACGACCGCATCGCCGGGCTGGAAGCCGGTGCCGACGACTACCTGACCAAACCGTTCAG
CCCGCGTGAGCTGGCGCTGCGCGTCCGGTCGGTGCTGCGACGCTCACCGGCCTCGATCGCGGCCCACCCGGTCGACATCA
CCTCCGGTGACCTGACCGTGTCGACGGCGTCGCGCTCGGCCACCGTCGGCGGCAGGACGGTCAGCCTGACCAATCGCGAG
TTCGACCTGCTGTTGTTCTTCCTGACCCACGCCGGCACCGTCTACACCCGCGAGGACCTCCTCAAAGAGGTGTGGCACTG
GGATTTCGGCGACCTGTCCACGGTCACCGTGCATGTGAAGCGACTGCGCTCCAAGCTCGGTGACCGGCACCGGGTACAGA
CCGTGTGGGGCCGCGGCTACATGTGGGCCCCCGACGAAGCGTCGCCCGGGCAGCCGGATGCTGCCGGCTGA

Protein sequence : 
MVTRVLIADDDGVVRDVVRRYLERDGLEVSTAHDGNEALRLLSSQRIDVAVLDVMMPGPDGMALCRRLRQNGHYSVPVIL
LTALGEEDDRIAGLEAGADDYLTKPFSPRELALRVRSVLRRSPASIAAHPVDITSGDLTVSTASRSATVGGRTVSLTNRE
FDLLLFFLTHAGTVYTREDLLKEVWHWDFGDLSTVTVHVKRLRSKLGDRHRVQTVWGRGYMWAPDEASPGQPDAAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CDB402_0209 YP_005126722.1 two-component system response regulator Not tested Not named Protein 3e-26 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_009782.5559369.p0 Protein 4e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002951.3237708.p0 Protein 4e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_003923.1003749.p0 Protein 3e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002758.1121668.p0 Protein 4e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_009641.5332272.p0 Protein 4e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_013450.8614421.p0 Protein 4e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_007793.3914279.p0 Protein 4e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002745.1124361.p0 Protein 4e-30 43
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002952.2859905.p0 Protein 5e-30 42
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_007622.3794472.p0 Protein 5e-30 42
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_012469.1.7685629. Protein 7e-28 42
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP001485.1.gene721.p Protein 1e-25 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG1389 Protein 1e-26 45
Mspyr1_07550 YP_004075290.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG1390 Protein 8e-28 43