Gene Information

Name : Mspyr1_47410 (Mspyr1_47410)
Accession : YP_004079117.1
Strain : Mycobacterium gilvum Spyr1
Genome accession: NC_014814
Putative virulence/resistance : Virulence
Product : chaperone ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4921499 - 4924042 bp
Length : 2544 bp
Strand : -
Note : PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA)

DNA sequence :
ATGTTCGAAAGATTCACCGACCGTGCGCGTCGGGTTGTCGTCCTGGCTCAAGAAGAGGCCCGGATGCTCAATCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGACTCATTCACGAGGGTGAAGGCGTGGCCGCCAAGTCACTCGAGTCGCTGGGCA
TCTCCCTGGAAGGGGTGCGCAGCCAGGTCGAGGAGATCATCGGTCAGGGACAGCAGGCGCCGTCCGGACACATCCCCTTC
ACTCCGCGGGCCAAGAAGGTGCTCGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTCATCCGCGAGGGTGAAGGCGTGGCCGCGCAGGTCCTCGTCAAGCTCGGCGCCGAGCTGACCCGGG
TGCGCCAGCAGGTCATCCAGCTGTTGAGCGGCTACCAGGGCAAGGAGACCGCCGAGGCCGGCACCGGCGGCCGCGGCGGG
GAGGCGGGCAATCCGTCCACGTCGCTGGTCCTCGACCAGTTCGGCCGCAACCTGACCGCTGCCGCGATGGAGGGCAAGCT
CGACCCCGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCGGTCC
TCATCGGAGAGCCCGGCGTCGGCAAGACCGCCGTCGTCGAAGGGCTCGCCCAGGCGATCGTGCACGGCGACGTGCCCGAG
ACGCTCAAGGACAAGCAGCTCTACACCCTCGACCTCGGATCGTTGGTCGCGGGCAGCCGCTACCGCGGTGACTTCGAGGA
ACGGCTGAAGAAGGTCCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTCGTCG
GCGCGGGTGCCGCCGAGGGCGCGATCGACGCGGCCAGCATCTTGAAGCCGAAGCTGGCCCGCGGCGAGCTGCAGACCATC
GGCGCGACCACCCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCGCTGGAGCGTCGCTTCCAGCCGGTCCAGGT
GGGCGAGCCGACCGTCGCGCACACCATCGAGATCCTCAAGGGTCTGCGCGACCGCTACGAGGCGCACCACCGCGTCTCCA
TCACCGACGGTGCGATCGCCGCGGCAGCGACGCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCGGGCGCGCGCATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAA
GATCGCCGATGCGCGCCGGGAGAAGGAGTCCGCGATCGACGCGCAGGACTTCGAGAAGGCCGCGAGCCTGCGCGACAAGG
AGAAGCAACTCGTCGCGCAGCGCGCCGAGCGCGAGAAGCAGTGGCGCTCAGGTGATCTCGACGTGGTCGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTCGGCAACTGGACCGGCATCCCGGTGTTCAAGTTGACCGAGGAGGAGACCACCCGTCT
CCTGCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCCGTCTCGAAGGCGATCCGCC
GCACGCGTGCGGGCCTGAAGGACCCGAAGCGCCCGTCCGGTTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAGCTCTCCAAGGCGCTGGCGAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCGTCGCGGCTATTTGGTGCCCCTCCGGGCTACGTCGGCTACGAAGAGGGCGGTCAGCTCACCGAGAAGG
TACGCCGCAAGCCGTTCTCGGTCGTGCTGTTCGACGAGATCGAGAAGGCCCACCAGGAGATCTACAACAGCCTCCTGCAG
GTGCTCGAAGACGGCCGCCTGACCGACGGTCAGGGCCGCACGGTGGACTTCAAGAACACCGTGCTGATCTTCACCTCGAA
CCTCGGCACCAGCGACATCAGCAAGGCGGTCGGACTGGGCTTCACCCAGGGCGGCGGCGATAACAACTACGAGCGGATGA
AGCAGAAGGTTCACGACGAACTGAAGAAGCACTTCCGTCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAGCTGACTCAGGACGAGATCATCCAGATGGTCGACCTGATGATCGGCCGGGTCGGCAACCAGCTCAAGGCCAAGGACAT
GGCCATGGAGCTGACGCCGAAGGCGAAGGCGCTGCTGGCCAAGCGTGGCTTCGATCCGGTGCTCGGTGCCCGGCCGCTGC
GCCGCACCATCCAGCGTGAGATCGAGGACCAGCTGTCCGAGAAGATCCTGTTCGAGGAGCTCGGGCCCGGTCAGCTCGTC
ACCGTCGACGTCGAGAACTGGGACGGCGAGGGCCAGGGCGAGGACGCGGTCTTCACGTTCAGCGGTGCGCGCAAGCCGGT
CGAGGTGGCCGAACCGGATCTGGCCCAGGCCGGAGCCGGTGGCGCGGGGCCCGCAGCCGAATAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKETAEAGTGGRGG
EAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGDNNYERMKQKVHDELKKHFRPEFLNRIDDIIVFH
QLTQDEIIQMVDLMIGRVGNQLKAKDMAMELTPKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELGPGQLV
TVDVENWDGEGQGEDAVFTFSGARKPVEVAEPDLAQAGAGGAGPAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 82

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_47410 YP_004079117.1 chaperone ATPase VFG0079 Protein 0.0 60
Mspyr1_47410 YP_004079117.1 chaperone ATPase VFG0080 Protein 3e-143 51