Gene Information

Name : Mspyr1_43690 (Mspyr1_43690)
Accession : YP_004078760.1
Strain : Mycobacterium gilvum Spyr1
Genome accession: NC_014814
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 4528985 - 4530508 bp
Length : 1524 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase family

DNA sequence :
ATGACTGTGTACGCCCGCCCCGGCGCCGACGGTTCGCTGATGTCGTTCAAGCCGCGCTATGACAACTTCATCGGCGGCCA
GTGGGTCGCACCCACCGCCGGTCGTTACTTCGAGAATCCGTCTCCGGTCACCGGCCAACCGTTCACCGAGGTTGCGCGGT
CCGACGAAGCGGACATCGAGAAGGCCCTCGACGCCGCCCACGCCGCGGCGCCGGCCTGGGGCAAGACGTCGGCCGCAGAG
CGTGCCGTGATCCTCAACAAGATCGCCGACCGCATCGAGGAGAACCTCGAGTCGATCTCGCTGGCCGAATCCTGGGACAA
CGGCAAGCCGATCCGGGAGACGCTGAACGCGGACCTGCCGCTGGCGGTCGATCACTTCCGCTACTTCGCCGGGTGCATCC
GCGCGCAGGAGGGTTCGCTCTCGGAGGTCGACGCCGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCCGTCTGGAAGCTCGCCCCGGCACTGGCGGCGGGCAATGCGGTGGT
GCTCAAGCCCGCCGAGCAGACGCCGGCGTCGATCCTGTACCTGATGGAGGTCATCGGCGACCTGCTGCCCGCCGGGGTGG
TCAACGTCGTCAACGGTTTCGGCGTCGAGGCGGGCAAACCGCTCGCGTCGAGCAACCGGATCGCGAAGATCGCGTTCACC
GGCGAGACCACGACCGGCCGGCTGATCATGCAGTACGCGTCGCAGAACCTGATTCCGGTGACGCTGGAACTGGGCGGCAA
GAGCCCGAACATCTTCTTCAACGACGTGCTCGCCGCCAGCGACGACTATCAGGACAAGGCGCTGGAGGGCTTCACGATGT
TCGCGCTGAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGGTCGCTGATCCAGGCCGACATCTACGACGAGTTCCTGGCG
CTGGCCGCGATCCGCACCAAGGCCGTGCGCCAGGGCGATCCGCTCGACACCGAGACGATGATCGGTGCACAGGCGTCCAA
CGATCAGCTCGAAAAGATCCTGTCCTACATCGAGATCGGCAAGAGTGAGGGCGCCAAGGTCGTCACCGGCGGCGAGCGTG
CCGAGCTCGGCGGCGACCTGAACGGCGGATATTACGTCGCGCCAACGATTTTCACCGGCAACAACACGATGCGGATCTTC
CAGGAGGAGATCTTCGGACCCGTCGTCGCCGTGACGTCGTTCACCGATTACGACGATGCGATCTCGCTCGCCAACGACAC
CCTCTACGGCCTCGGGGCCGGGGTGTGGAGCCGCAACGGCAACACCGCCTACCGGGCCGGGCGCGACATCAAGGCCGGGC
GGGTGTGGACGAACTGCTACCACCAGTACCCCGCGCACGCGGCGTTCGGCGGCTACAAACAGTCCGGCATCGGCCGCGAG
AACCACAGGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACAGCGACCAGGCCCTCGGATTCTT
CTGA

Protein sequence :
MTVYARPGADGSLMSFKPRYDNFIGGQWVAPTAGRYFENPSPVTGQPFTEVARSDEADIEKALDAAHAAAPAWGKTSAAE
RAVILNKIADRIEENLESISLAESWDNGKPIRETLNADLPLAVDHFRYFAGCIRAQEGSLSEVDADTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPASILYLMEVIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAASDDYQDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLA
LAAIRTKAVRQGDPLDTETMIGAQASNDQLEKILSYIEIGKSEGAKVVTGGERAELGGDLNGGYYVAPTIFTGNNTMRIF
QEEIFGPVVAVTSFTDYDDAISLANDTLYGLGAGVWSRNGNTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRE
NHRMMLDHYQQTKNLLVSYSDQALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-143 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-151 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-151 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-151 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-151 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-65 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_43690 YP_004078760.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 2e-143 63