Gene Information

Name : Mspyr1_29350 (Mspyr1_29350)
Accession : YP_004077389.1
Strain : Mycobacterium gilvum Spyr1
Genome accession: NC_014814
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3045602 - 3047020 bp
Length : 1419 bp
Strand : -
Note : PFAM: pyruvate kinase, barrel domain; pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
GTGACTCGACGCGGAAAAATCGTCTGTACGCTCGGCCCGGCCACCGCCTCGGACGAAGCGGTCAGGCAGTTGGTCGAGTC
CGGAATGGACGTCGCGAGGCTCAACTTCAGCCACGGTGACTACCCCGACCACGAGGCCAATTACAAGCGGGTCCGGGCCG
CGTCCGACGCGACCGGGCGCGCCGTCGGAATCCTCGCGGACCTGCAGGGACCGAAGATCAGACTGGGTCGGTTCGCCGAC
GGCCCGACCGTCTGGCGCAACGGTGAGACGATCCGGATCACCGTCGACGACTTCGAGGGCACCCACGACCGGGTGTCGAC
GACCTACAAGCGGCTGGCGCAGGACGCCACGCCCGGCGACCGCGTCCTCGTCGACGACGGCAACGTGGGTCTGGTCGTCG
AGCACATCGACGGCAATGACGTCGTCTGCACGGTCACCGAGGGCGGCAAGGTCAGCAACAACAAGGGCATGTCGCTGCCC
GGCATGAACGTATCGGCGCCGGCGCTGTCGGAGAAGGACATCGACGACCTGGAGTTCGCGCTGCGCCTGGGCGTCGACCT
GGTGGCGCTGTCGTTCGTGCGTTCACCCGCCGACGTCGAACTCGTCCACGAGATCATGGACCGCGTGGGGCGCCGCGTGC
CGGTCATCGCGAAGCTGGAGAAGCCGGAGGCGATCGACAACCTCGAGGCGATCGTGCTGGCCTTCGACGCGATCATGGTC
GCCCGCGGTGACCTGGGTGTCGAGCTGCCGCTCGAAGAGGTGCCGCTGGTGCAGAAGCGTGCGATCCAGATGGCAAGGGA
GAACGCCAAACCCGTCATCGTGGCCACGCAGATGCTGGAGTCGATGATCGAGAACTCGCGACCCACCCGGGCGGAGGCCT
CCGACGTCGCCAACGCGGTGCTCGACGGGGCGGACGCGGTGATGCTGTCCGGGGAGACCTCGGTGGGCAAGTTCCCCTTC
GAGACGGTCCGCACGATGGCCCGCATCGTCAGCGCCGTCGAGGACAACTCGGTCGCCGTGCCTGCCCTGACCCACACGCC
GCGCACCAAACGCGGGGTGATCTCCTACGCCGCGCGCGACATCGGCGAACGTCTCGACGCCAAGGCGTTGGTCGCGTTCA
CCCAGTCCGGCGACACGGTGCGCCGTCTGGCCCGTCTGCACACCCCGCTGCCGGTGCTGGCGTTCACCTCGCTGCCCGAG
GTGCGCAGCCAGCTGGCGCTGACGTGGGGCACCGAGACGTTCATCGTCCCGCACATCGACACCACCGACGGGATGATCCG
GCAGGTCGACCAGTCGATGCTCAACCTCGGCCGCTACAAGAGGGGCGACCTGGTGGTCATCGTCGCGGGTGCGCCTCCCG
GCACAGTAGGCTCCACCAATCTGATCCACGTCCACCGCATCGGGGAGGACGACGTTTAA

Protein sequence :
MTRRGKIVCTLGPATASDEAVRQLVESGMDVARLNFSHGDYPDHEANYKRVRAASDATGRAVGILADLQGPKIRLGRFAD
GPTVWRNGETIRITVDDFEGTHDRVSTTYKRLAQDATPGDRVLVDDGNVGLVVEHIDGNDVVCTVTEGGKVSNNKGMSLP
GMNVSAPALSEKDIDDLEFALRLGVDLVALSFVRSPADVELVHEIMDRVGRRVPVIAKLEKPEAIDNLEAIVLAFDAIMV
ARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKFPF
ETVRTMARIVSAVEDNSVAVPALTHTPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPVLAFTSLPE
VRSQLALTWGTETFIVPHIDTTDGMIRQVDQSMLNLGRYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-67 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-67 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-67 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_29350 YP_004077389.1 pyruvate kinase VFG0479 Protein 2e-67 41