Gene Information

Name : Mspyr1_28860 (Mspyr1_28860)
Accession : YP_004077343.1
Strain : Mycobacterium gilvum Spyr1
Genome accession: NC_014814
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 2992940 - 2996245 bp
Length : 3306 bp
Strand : +
Note : PFAM: tRNA synthetases class II (D, K and N); conserved protein (DUF2156); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial

DNA sequence :
ATGACCGCAACCCGCCTCGTCAGGGCGCATCCCGAGTCCAGTCACCGGTGGGTGCCCGCGGCGGCCGGCTGGATCGTGGG
TGTGATCGCCACGTTGTCCCTGCTGGCGAGCGTGTCACCGCTGGTCCGCTCGATCATCCGCGTTCCCCGCGAGTTCGTCG
ACGACTACATCTTCAACTTCCCGGACACGAGCTTCGCGTGGGCGTTCGTGCTGGCGCTGCTCGCGGCCGCGCTCGCTGCC
CGCAAACGCATCGCCTGGTGGATCCTGACCGGCTACATGGTGGCCGCGGCCGTCTGGAACGTCACCGGACTGCTCGACGG
TGACCGGTGGTTCGAGGACGTCGGCGAGATCATCGGCCTGGGCTTCCACCTCGCCGCCATCGCGTCTCTGCTGTTGGCCC
GCAGGGAATTCTGGGCCCGGGTGCGCCCGGGCGCGCTCGTCAAGGCGGCAGTCACCCTGGTCGCGGGCCTGGCCGTCGGC
ACGCTGATCGGCTGGGGTCTGCTCAAATTGTTCCCCGGCACCCTGGCCCGGCCTGATCGCTTCTGGTACGCGCTCAACCG
GGTCGGCGCCTTCGCGGGGGCGGATGCCGGCGCGTTCTCCGGCCACCCGCACGTGCTGGTCAACGCCCTCCTCGGCCTGT
TCGGCGCGATGGCCCTGATGATCGCGGCGGTCGTGCTGTTCCAGTCACAGCGTGCGGACAACGCGCTGACCGGTGAGGAC
GAATCCGCCATCCGCGGTCTGCTGGAGCTGTACGGGAAGAACGATTCGCTGGGCTATTTCGCGACGCGTCGCGACAAGGC
GGTGGTCTTCGCCCCGAACGGACGGGCCGCGATCACCTACCGGGTCGAGGTCGGCGTGTGCCTGGCCAGCGGCGACCCGG
TCGGCGACCCGAAGGCGTGGCCGCAGGCCATCGAGGCGTGGCTGACGTTGTGTGAGACCTACGGGTGGGCGCCGGGTGTC
ATGGGCGCCAGCGCGACCGGCGCACAGGCGTTCCGCCAGGCGGGCCTGCACGCGCTGCAACTCGGCGACGAAGCGATCCT
GCATCCGGACGATTTCCGTCTCTCCGGACCCGAGATGCGCGCGGTGCGCCAAGCCGTCACCCGCGCTCGACGCGCCGGCG
TCGCCGTGCGCTTCCGCAGACACCGCGAGTTGTCACCCGACGAGATGGCCGAGGTGATCGCGCACGCCGACGCCTGGCGT
GACACCGAGGACGAGCGCGGATTCTCGATGGCGCTGGGCCGGCTCGGTGACCCCGCCGACGCCGACTGCCTCCTGGTGGA
GGCCGTACAGAACGGGACCCAGGTCGTCGCGATGCTGTCGCTGGTGCCGTGGGGCAGCAACGGTGTGTCACTGGACCTGA
TGCGACGTGCCCCCCAATCCCCCAACGGCACCATCGAATTGATGGTCAGCGAGCTGTGCCTGCAATCCGAGAGCATCGGC
ATCAGCCGGATCTCGCTGAACTTCGCGATGTTCCGCTCGGCGTTCGAGCAGGGCGCACAACTCGGCGCCGGCCCGGTGGC
CCGGCTGTGGCGTTGGCTGCTGGTCTTCTTCTCGCGCTGGTGGCAGTTGGAGACGCTGTACCGCTCCAACATGAAGTACC
GGCCCGAATGGGTGCCCCGCTACGCGTGTTACGAGGACGCCCGGCTGGTGCCCAGGGTCGGGGTCGCCTCGGTCATCGCC
GAAGGCTTTCTGGTGCTTCCCTTCTCGCGGCGCCACGATCAACCCCACACGGGGCACCACATCGCCGCACCGGGCGACCT
GATCGCCACCGGACGCCTGCACAGCGACGGAACGGCACCCGACCGCATCGGGCCCGTGGGCGACGGGGCCGACGACGACG
CCGCCCCGCGCCTGCCCGAGCAGGTCCGGGTGCGGATGGCGAAGCTCAGCGCCCTGCAGGACCGGGGCGTCGACGCCTAC
CCCGTGGGCAGCCCGCCCAGCCACACCATCGCCGAGGCGATCGCCGCCGAGGAAGGCACCGAGGTCACGGTGTCCGGCCG
GGTTCTGCGGGCCCGCGACTACGGTGGTGTGCTCTTCGGTCAGCTACGCGACTGGTCCGCCGAAACCCAGGTGGCGCTGG
ACAATTCGGCGCTGCTCGACGGAACCACCACCGACTTCACCCGCACCGTCGACCTCGGCGACCTGATCGAGGTGACCGGC
ACGATGGGCCACACCCGGTCGGGTTCGTGGTCGGTGCTGGTGACCCGGTGGCGGTTGATCGGCAAGTGCCTGCGGCCGCT
GCCCGACAAGTGGAAGGGGTTGACCGACCAGGAGGCGCGGGTGCGCGCCCGCTACGTCGACCTCGCGGTCAACACCGACG
CCCGCGAACTCATCAAGGCCCGCAGCGCCATTCTGCACGCCATCCGCGAAACCCTGGTCGGCAAAGGCTTTCTCGAGGTC
GAGACGCCGATCCTGCAGCAGATCCACGGCGGCGCCAACGCGCGTCCGTTCCTGACCCACATCAACGCCTACGACCTGGA
CCTGTATCTGCGGATCGCACCCGAGTTGTATCTGAAGAGGCTCTGTGTCGGGGGCGTCGAGCGGGTCTTCGAGCTGGGCC
GGGCGTTCCGGAACGAGGGGGTCGACTTCAGCCACAATCCCGAATTCACCCTGCTGGAGGCCTACCAGGCGCACGCGGAC
TACACCGTGTGGATCGACGGGTGCCGCGAGCTGATCCAGAACGCGGCCATGGCCGCCAACGGCTCCCACGTGTTCTTCCG
TCCGCGCGAGGACGGGGTCCTCGAACCGGTCGACATCTCCGGCCGATGGGCGGTCAAGACGGTTCACGGCGCGGTGTCGG
AGGCACTCGGCGAGCACATCGACGTCGACACCGACCTGGCGACGCTGCGCCGCCTCTGCGACAAGGCCGGCATCCCCTAC
CTGACGCACTGGGACGCCGGCGCGGTGGTCCTCGAGATGTACGAGCACCTCGTCGAGGACCAGACCACCGAACCCACCTT
CTACAAGGACTTCCCGACGTCCGTGTCGCCGCTGACCCGGCCGCACCGCAGCATCCCGGGGGTCGCCGAACGCTGGGACC
TCGTCGCGTGGGGGGTCGAGCTCGGCACCGCCTACAGCGAACTGACCGACCCTGTGGAGCAGCGCCGCAGGTTGCAGGAG
CAGTCGCTGCTGGCCGCAGGCGGCGACCCGGAGGCGATGGAGCTCGACGAGGACTTCCTGCAGGCGATGGAGTACGCGAT
GCCGCCGACCGGAGGCCTCGGAATGGGTGTCGATCGGGTGGTCATGCTGATCACCGGGCGCAGCATCCGCGAGACGCTGC
CGTTCCCGCTCGCGAAACCGAGGTAG

Protein sequence :
MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASVSPLVRSIIRVPREFVDDYIFNFPDTSFAWAFVLALLAAALAA
RKRIAWWILTGYMVAAAVWNVTGLLDGDRWFEDVGEIIGLGFHLAAIASLLLARREFWARVRPGALVKAAVTLVAGLAVG
TLIGWGLLKLFPGTLARPDRFWYALNRVGAFAGADAGAFSGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALTGED
ESAIRGLLELYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIEAWLTLCETYGWAPGV
MGASATGAQAFRQAGLHALQLGDEAILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPDEMAEVIAHADAWR
DTEDERGFSMALGRLGDPADADCLLVEAVQNGTQVVAMLSLVPWGSNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIG
ISRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYRPEWVPRYACYEDARLVPRVGVASVIA
EGFLVLPFSRRHDQPHTGHHIAAPGDLIATGRLHSDGTAPDRIGPVGDGADDDAAPRLPEQVRVRMAKLSALQDRGVDAY
PVGSPPSHTIAEAIAAEEGTEVTVSGRVLRARDYGGVLFGQLRDWSAETQVALDNSALLDGTTTDFTRTVDLGDLIEVTG
TMGHTRSGSWSVLVTRWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARELIKARSAILHAIRETLVGKGFLEV
ETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHAD
YTVWIDGCRELIQNAAMAANGSHVFFRPREDGVLEPVDISGRWAVKTVHGAVSEALGEHIDVDTDLATLRRLCDKAGIPY
LTHWDAGAVVLEMYEHLVEDQTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQE
QSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 8e-152 44
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-151 44
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 8e-152 44
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 8e-152 44