Gene Information

Name : Mspyr1_26830 (Mspyr1_26830)
Accession : YP_004077149.1
Strain : Mycobacterium gilvum Spyr1
Genome accession: NC_014814
Putative virulence/resistance : Virulence
Product : urease
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2750733 - 2752454 bp
Length : 1722 bp
Strand : -
Note : PFAM: Amidohydrolase family; Urease alpha-subunit, N-terminal domain; TIGRFAM: urease, subunit alpha

DNA sequence :
ATGACCCGGCTCACCCGGACCCACTACGCGGTGCTGTTCGGACCCACGACGGGGGATCGCATCCGCCTGGCAGACACCGA
TCTGTTCATCGAGATCACCGAGGACCGCAGCGGCGGACCCGGCCTTGCCGGCGACGAGGCCGTCTTCGGCGGAGGCAAGG
TCCTGCGCGAATCGATGGGCCAGTCACGGGCCACGCGCGCCGACGGCGCCCCCGACACGGTCATCACCGGCGCGGTGATC
CTGGACCATTGGGGAATCATCAAGGCCGACATCGGCATTCGTGACGGTCGTATCGTCGGGATCGGGAAGGCGGGTAACCC
CGACATCATGTCGGGGGTACATCCCGCCCTCGTCGTGGGGCCGTCCACCGAGATCATCGCGGGCAACGGCCGCATCGTCA
CCGCGGGCGCAATCGACTGCCATGTGCACCTGATCTGCCCGCAGATCATGGAGGAAGCGCTCGGTGGTGGGATCACGACC
ATCATCGCGGGTGGGACCGGCCCGGCCGAGGGCAGCAAGGCCACCACCGTGACCCCGGGTGCCTGGCATCTGGCCAGGAT
GCTGGAGGCGCTCGACACCTGGCCGATGAACGTCGCGCTGCTGGGCAAGGGCAACACCGTCAGCAGCGAGGCGATGTGGG
AGCAATTACGCGGCGGCGCAGCGGGTTTCAAACTGCACGAGGACTGGGGCACCACCCCCGCGGCGATCGACGCCTGCCTG
ACGGTGTGCGAACAAGCCGGTGTGCAGGCCAACATCCACACCGACACCCTCAACGAGGCGGGTTTCGTCGAGGACACGCT
CGCCGCGATCAAGGGCCGCTCGATCCACGCGTACCACACCGAGGGCGCCGGCGGTGGGCACGCACCCGACATCATCACTG
TCGCAGGCCATCCCAATGTGCTGCCCAGCTCGACCAACCCCACGCGACCGCACACGGTGAACACCCTCGACGAGCATCTC
GACATGCTGATGGTGTGCCATCATCTCAACCCGCGGGTGCCCGAGGATCTCGCCTTCGCCGAAAGCCGGATCCGGCCGTC
GACGATCGCGGCCGAGGACCTGCTGCACGACATCGGCGCGATCTCGATGATCGGCAGTGACGCCCAGGCGATGGGCCGCA
TCGGCGAGGTCGTGATGAGGACGTGGCAGACCGCGCACGTGATGAAGCGCCGGCGTGGCTTCCTGCCGGGGGACACCCGC
GCCGACAACACCCGCGCGCAACGCTATGTCGCGAAGTACACCATCTGCCCGGCCGTCGCGCACGGGCTCGACGGGGAGAT
CGGCTCGGTCGAGGTCGGCAAGCTCGCCGACCTGGTGCTGTGGGAGCCCGCGTTCTTCGGGGTGCGTCCGCACGCCGTCG
TGAAGGGCGGCATGATCGCGTGGGCGGCGATGGGCGATGCGAACGCGTCGATTCCGACACCGCAGCCGGTGTTGCCGCGA
CCGATGTTCGGCGCGGCCCCGGCCGCGGCGGCCCACACGTCGGTGCATTTCGTCGCACCGCAGGCCATCGAGGACGGCCT
CGCCGACCGGATTGCGGTGCACCGCAAGCTCGTTGCGGTCGGCAACGTCCGCGCGGTCGGCAAGGCCCAGATGCCGGGCA
ACGACGCGACACCGGACATCCGGGTCGATCCGGACACCTTCACCGTCCGCATCGACGGGGAGGTCTGGGAGGAGCAGCCC
GCCGAAGAACTCCCCATGGCCCAACGTTACTTCCTCTTCTAG

Protein sequence :
MTRLTRTHYAVLFGPTTGDRIRLADTDLFIEITEDRSGGPGLAGDEAVFGGGKVLRESMGQSRATRADGAPDTVITGAVI
LDHWGIIKADIGIRDGRIVGIGKAGNPDIMSGVHPALVVGPSTEIIAGNGRIVTAGAIDCHVHLICPQIMEEALGGGITT
IIAGGTGPAEGSKATTVTPGAWHLARMLEALDTWPMNVALLGKGNTVSSEAMWEQLRGGAAGFKLHEDWGTTPAAIDACL
TVCEQAGVQANIHTDTLNEAGFVEDTLAAIKGRSIHAYHTEGAGGGHAPDIITVAGHPNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLNPRVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVMRTWQTAHVMKRRRGFLPGDTR
ADNTRAQRYVAKYTICPAVAHGLDGEIGSVEVGKLADLVLWEPAFFGVRPHAVVKGGMIAWAAMGDANASIPTPQPVLPR
PMFGAAPAAAAHTSVHFVAPQAIEDGLADRIAVHRKLVAVGNVRAVGKAQMPGNDATPDIRVDPDTFTVRIDGEVWEEQP
AEELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 9e-148 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 9e-148 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-147 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-147 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 7e-147 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-147 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_26830 YP_004077149.1 urease VFG0270 Protein 2e-130 54