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Name : Mspyr1_25000 (Mspyr1_25000) Accession : YP_004076973.1 Strain : Mycobacterium gilvum Spyr1 Genome accession: NC_014814 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : 1.16.1.1 Position : 2583861 - 2585264 bp Length : 1404 bp Strand : + Note : PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: mercuric reductase DNA sequence : ATGAGTCAGGGATTGGACCTCGCGGTCATAGGTTCCGGCGGCGCGGCGATGGCCGCGGCGATCCGCGCTACCGCGCTCGG CAAGTCCGTCGTCATGATCGAGCGCGGCATCTTCGGTGGCACGTGTGTCAACACCGGCTGCGTGCCGTCAAAGGCCCTGA TCGCAGCGGCCGAGGCCCGGCATACCGCAGCCGACACTGCCCGGTTCCCGGGGATCGCCACCACGGCCGGCCCGGTGGAC ATGGCGGCCCTGATCGCCGGCACGCACGATCTGGTGGAGTCGCTGCGCTCAGAGAAGTACCTCAACGTGGCCGAATCGTA TGGCTGGCAGCGCATTCAGGGCCAAGCGCGGTTCGCCGGAACCCCGGACGCGCCCGTCATCGAGGTCGGCGATGCCACCA TCGAGGCCGAGCACTACCTGATCGCCACCGGCGCGAACCCAGTCATCCCGCCCGCATTCGAGGGCGTCGCCTACCTGACC TCGACCACCGCGATGGAAGTCACCGAGGTCCCGGAGTCGCTGCTGGTGATCGGCGGCGGCTACGTCGCGTTGGAGCAGGC GCAACTGTTCGCCCGGCTCGGGTCAACGGTGACGGTGCTGGTCCGCTCCACGCTGGCATCGAAGGAAGAGCCGGAAGTCG GCATGGCGCTGCTGGAGGTGTTCGCCGACGACGGCATCCGGGTGGTGCGCCGCGCCACGGTGAGCGAGGTCGAGCAGGCC GACGATCAGGTCACGGTCACCGCGACCATCACCGGCGGAACGCAGCAGTTCCGTGCCGCGAAAGTCCTCGTCGCCACCGG CCGCCGTCCGAACACCGACGGCCTGAATCTCGAAGCGGTGCAGGTCAAAACCGGCGAGAACAACGAGGTCGTGGTGAGCG ACGGGCTGCAGTCGTCGAACCCACGGATCTGGGCGGCCGGCGACGTGACCGGGCACCGCGAGTTCGTCTACGTCGCCGCC CATCACGGCGCGATGGTCGCCGACAACATCTTCACCGACGCCGGCCGCAGGGTCGACTACCGCCATCTGCCCCGCGTGAC GTTCACCAGCCCCGCGGTCGGTGCGGCCGGGACGACCGAGGCCGAGCTCCTCGCCGCCGGGACACGGTGCGACTGCCGGG TGCTGCCGCTAAAACATGTGCCGCGTGCGGTGGTCAACCGAGACACCCGCGGTTTCATCAAACTCGTCGCCGACGCCGGC ACCGGCCGCATCCACGGCATCACCGCCGTCGCCAAGGATGCTGGCGAGATCGCCGCCGCCGCGGTCTACATCCTCGACGC CGCGATGACCGTCGACCAGGTCGCCGGGTCCTGGGCCCCGTATCTGACCATGGCCGAAGGCATCAAAATCGCCGCCCAGT CCTTCAGCGCCGATATGTCCCGACTGTCCTGCTGCGCATCCTGA Protein sequence : MSQGLDLAVIGSGGAAMAAAIRATALGKSVVMIERGIFGGTCVNTGCVPSKALIAAAEARHTAADTARFPGIATTAGPVD MAALIAGTHDLVESLRSEKYLNVAESYGWQRIQGQARFAGTPDAPVIEVGDATIEAEHYLIATGANPVIPPAFEGVAYLT STTAMEVTEVPESLLVIGGGYVALEQAQLFARLGSTVTVLVRSTLASKEEPEVGMALLEVFADDGIRVVRRATVSEVEQA DDQVTVTATITGGTQQFRAAKVLVATGRRPNTDGLNLEAVQVKTGENNEVVVSDGLQSSNPRIWAAGDVTGHREFVYVAA HHGAMVADNIFTDAGRRVDYRHLPRVTFTSPAVGAAGTTEAELLAAGTRCDCRVLPLKHVPRAVVNRDTRGFIKLVADAG TGRIHGITAVAKDAGEIAAAAVYILDAAMTVDQVAGSWAPYLTMAEGIKIAAQSFSADMSRLSCCAS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 1e-79 | 44 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 9e-80 | 44 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 2e-63 | 44 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 6e-64 | 43 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 6e-66 | 43 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 6e-66 | 43 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 6e-66 | 43 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 1e-64 | 43 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 1e-64 | 43 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 2e-63 | 42 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 2e-63 | 42 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 2e-63 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Mspyr1_25000 | YP_004076973.1 | mercuric reductase | BAC0651 | Protein | 6e-80 | 44 |
| Mspyr1_25000 | YP_004076973.1 | mercuric reductase | BAC0652 | Protein | 2e-66 | 44 |
| Mspyr1_25000 | YP_004076973.1 | mercuric reductase | BAC0653 | Protein | 3e-63 | 42 |
| Mspyr1_25000 | YP_004076973.1 | mercuric reductase | BAC0650 | Protein | 1e-61 | 42 |
