Gene Information

Name : Mspyr1_24840 (Mspyr1_24840)
Accession : YP_004076959.1
Strain : Mycobacterium gilvum Spyr1
Genome accession: NC_014814
Putative virulence/resistance : Virulence
Product : ABC-type Mn2+/Zn2+ transporter permease
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 2568468 - 2569412 bp
Length : 945 bp
Strand : -
Note : PFAM: ABC 3 transport family

DNA sequence :
ATGACCGTCGTCGAGTTCCTCGTCGAACCGCTGCAGCTGGAGTTCATGGTCCGCGCCACCGTCACGACGCTCATCGCGTC
GACTGTGTGCGCCACGCTGTCGTGCTGGCTCGTTCTCATCGGCTGGTCGTTGATGGGAGACGCGGTATCACACGCCGTCC
TTCCCGGCGTCGTGCTGGCCCACATCGTCGGTGCACCGTTTGCGTTGGGCGCCATCATTTTCGGCTTCGTCGCGGTCGGA
CTCATCGGCGTCGTCCGAGACACCAGCCGCACCAAGGAAGACGCCGCCATCGGGGTCGTCTTCACGACCCTGTTCGCGCT
CGGACTGGTGCTGATCTCGGTGACGCCCAGTCAGGTCGATCTCAACCACATCATCTTCGGCAACGTGCTCGGTGTCTCCC
GGGCCGACCTCATCCAGGTGGCCGTCCTCGGCACCGTCGTGATGGCGGTCATGGTCTACAAACGTCGCGACTTCACCCTC
TACGCCTTCGATCCCCACCACGCCCACGCGATCGGACTCAATCCCCGCCTGCTGGGCGCCGCCCTGCTCGGATTGCTCGC
TCTGACCGCGGTCGTGGCGCTGCAGGCCGTGGGAGTCGTTCTCGTGGTCGCCCTGCTCATCACTCCCGGTGCGACCGCCT
ACCTGATCACAGAGCGGTTCAGCCGCATGCTGCTCATCGCACCGACGATCGCCGCGGTCTGCGCACTGACCGGCCTGTAC
GCGAGCTACTACCTCGACACCGCGTCCGGGCCGATGGTCGTGCTGGCCAACGGCACAGCGTTCGCGCTCGCCTACCTCGC
TCGTCTCGGCCGGGAACAGCGCACCCGGCACCACCGCCCCGGCGTCAGAGCACCTTGGACAGAAACTCCTGCAGCCGAGG
ATGCTTCGGATTGTCGAAGATCTCGGCGGGCGGGCCTTCCTCGACGATGTGGCCGTCGGCCATGA

Protein sequence :
MTVVEFLVEPLQLEFMVRATVTTLIASTVCATLSCWLVLIGWSLMGDAVSHAVLPGVVLAHIVGAPFALGAIIFGFVAVG
LIGVVRDTSRTKEDAAIGVVFTTLFALGLVLISVTPSQVDLNHIIFGNVLGVSRADLIQVAVLGTVVMAVMVYKRRDFTL
YAFDPHHAHAIGLNPRLLGAALLGLLALTAVVALQAVGVVLVVALLITPGATAYLITERFSRMLLIAPTIAAVCALTGLY
ASYYLDTASGPMVVLANGTAFALAYLARLGREQRTRHHRPGVRAPWTETPAAEDASDCRRSRRAGLPRRCGRRP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 4e-40 46
sitD NP_461785.1 permease Virulence SPI-1 Protein 3e-40 46
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 2e-40 46
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-40 46
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 4e-40 46
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 3e-38 41
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-38 41
sitC NP_461784.1 permease Virulence SPI-1 Protein 5e-38 41
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 4e-38 41
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 4e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_24840 YP_004076959.1 ABC-type Mn2+/Zn2+ transporter permease BAC0352 Protein 1e-40 46
Mspyr1_24840 YP_004076959.1 ABC-type Mn2+/Zn2+ transporter permease BAC0442 Protein 2e-41 44
Mspyr1_24840 YP_004076959.1 ABC-type Mn2+/Zn2+ transporter permease BAC0441 Protein 6e-35 42
Mspyr1_24840 YP_004076959.1 ABC-type Mn2+/Zn2+ transporter permease BAC0351 Protein 2e-38 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mspyr1_24840 YP_004076959.1 ABC-type Mn2+/Zn2+ transporter permease VFG0528 Protein 1e-40 46
Mspyr1_24840 YP_004076959.1 ABC-type Mn2+/Zn2+ transporter permease VFG0527 Protein 2e-38 41