Gene Information

Name : fliI (HFELIS_13770)
Accession : YP_004074051.1
Strain : Helicobacter felis ATCC 49179
Genome accession: NC_014810
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1353029 - 1354339 bp
Length : 1311 bp
Strand : +
Note : -

DNA sequence :
ATGTCCTTAGAATCCCTCAAAGCCCGCCTGCAACTTGTGCGCGATCTCTCGCCCCGCTATGGCATGGTTTGCAAAATTTT
ACCCAATATGGTTTTTGTGCAGGGGTTTTTACCCTCTGTAGGGGATGTGGTCAAGGTGGAGCGGGGCGATGGCAAGGAAT
GTTTAGGCATGGTGGTGGTGGTGGAGCAAACACAATTTGGCTTTGCGCCCTTTTCCTTTGTGGAGGGGTGCAAGGTGGGG
GATCGCGTACTCTTTGTCAAAGAGGGTTTGAGTTTCCCTGTGGGGGAGGGTTTGCTAGGGCGCGTACTCGATCCGCTAGG
CAATCCCCTAGATGAATTAGGCTTTGTGCGCGCCAGTGCTTTTGCGCCCGTGATGGTAGAACCTATGAAACCCCTAGATC
GGGGCGTGATCGATGAACCCTTTGGGGTAGGGGTTAAGAGCATTGATGCTTTGCTGACTTGTGGTAAGGGGCAGAAACTA
GGCATTTTTGCAGGGAGTGGGGTGGGCAAATCTACTCTGATGGGCATGGTGGTGCGCGGGTGCAGTGCGCCCATCAAGGT
GATCGCCCTCATTGGGGAGCGGGGGCGTGAGATTCCGGAGTTTATCCATAAAAATCTGCAAGGTAATTTGGATAATACCG
TGCTTGTGGTCGCTACTAGCGATGATTCCCCTTTAATGCGCAAATACGGCGCGTTCTGCGCGATGAGTGTGGCGGAGTAT
TTTAAAAATCAAGGGCATGATGTCTTATTTATGATGGACTCTATTACGCGCTTTGCAATGGCACAACGCGAGATCGGACT
GGCGATGGGCGAGCCTCCTACTAGCAAGGGTTATCCCCCCTCTGCGCTCACCTTACTACCCCAGCTGATGGAACGCGCGG
GCAAGGAGAAAAATAAAGGGAGCATTACGGCGTTTTTCACCGTTCTCGTTGAAGGCGATGATCTCTCTGATCCCATTGCC
GATCAGGCGCGCAGTATTTTAGATGGGCATATTGTTTTGAGCCGTGAGCTCACCGATCATGGCATTTACCCCCCCATCAA
TATTTTAAACTCCGCCTCTAGGGTGAGCAAAGAGGTGAGTGCGACAGAACACATGTTAGCTGCGCGCAAATTCCGCAAAC
TTCACGCCTTGCTCAAAGAAAACGAGGTTTTGATTCGCATAGGCTCTTACCAACCCGGGTTTGATGCAGACCTAGATGAA
GCAATCGCCAAAAAGGCGGGCATGGAAGCTTTTATGTTACAAGAAGAAGAGGAGATTGTACCCAGTAATACCAGTATCCA
GCAGTTGATCGCGCTTATGCAAGAATCTTAA

Protein sequence :
MSLESLKARLQLVRDLSPRYGMVCKILPNMVFVQGFLPSVGDVVKVERGDGKECLGMVVVVEQTQFGFAPFSFVEGCKVG
DRVLFVKEGLSFPVGEGLLGRVLDPLGNPLDELGFVRASAFAPVMVEPMKPLDRGVIDEPFGVGVKSIDALLTCGKGQKL
GIFAGSGVGKSTLMGMVVRGCSAPIKVIALIGERGREIPEFIHKNLQGNLDNTVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGHDVLFMMDSITRFAMAQREIGLAMGEPPTSKGYPPSALTLLPQLMERAGKEKNKGSITAFFTVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDHGIYPPINILNSASRVSKEVSATEHMLAARKFRKLHALLKENEVLIRIGSYQPGFDADLDE
AIAKKAGMEAFMLQEEEEIVPSNTSIQQLIALMQES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 9e-77 50
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-77 47
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-78 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-78 47
escN AAL57542.1 EscN Virulence LEE Protein 2e-77 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-77 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 9e-78 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-77 47
escN AAC31513.1 L0034 Virulence LEE Protein 7e-78 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-78 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 9e-78 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 9e-78 47
escN AAC38383.1 EscN Virulence LEE Protein 4e-78 47
escN AAK26715.1 EscN Virulence LEE Protein 2e-77 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-77 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-77 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 9e-79 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-77 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-78 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-78 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-78 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-76 43
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-76 43
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-76 43
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-77 43
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-57 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 4e-61 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-54 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-54 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-54 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-54 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-56 43
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-68 42
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-68 42
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-68 42
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-68 42
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-68 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-64 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-63 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-63 42
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-58 42
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-58 42
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 6e-70 41
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-57 41
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 8e-57 41
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-64 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_004074051.1 flagellum-specific ATP synthase VFG0048 Protein 1e-80 54
fliI YP_004074051.1 flagellum-specific ATP synthase VFG0390 Protein 4e-79 50
fliI YP_004074051.1 flagellum-specific ATP synthase VFG0192 Protein 3e-78 50
fliI YP_004074051.1 flagellum-specific ATP synthase VFG2331 Protein 2e-71 50
fliI YP_004074051.1 flagellum-specific ATP synthase VFG1254 Protein 4e-78 48
fliI YP_004074051.1 flagellum-specific ATP synthase VFG0812 Protein 4e-78 47
fliI YP_004074051.1 flagellum-specific ATP synthase VFG0730 Protein 2e-78 47
fliI YP_004074051.1 flagellum-specific ATP synthase VFG1008 Protein 2e-61 46
fliI YP_004074051.1 flagellum-specific ATP synthase VFG2144 Protein 2e-72 45
fliI YP_004074051.1 flagellum-specific ATP synthase VFG1778 Protein 5e-59 44
fliI YP_004074051.1 flagellum-specific ATP synthase VFG0555 Protein 7e-55 43
fliI YP_004074051.1 flagellum-specific ATP synthase VFG0515 Protein 2e-68 42