Gene Information

Name : ureB2 (HFELIS_13570)
Accession : YP_004074031.1
Strain : Helicobacter felis ATCC 49179
Genome accession: NC_014810
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1331010 - 1332716 bp
Length : 1707 bp
Strand : +
Note : -

DNA sequence :
ATGAAAATGAAAAAACAAGAATATGTAAATACCTACGGACCCACCAAAGGCGATAAAGTGCGCTTAGGAGATACCGATCT
TTGGGCAGAAGTAGAACATGACTATACCACCTATGGCGAAGAACTTAAATTTGGCGCGGGTAAAACTATCCGTGAGGGTA
TGGGTCAGAGCAATAGCCCTGATGAAAACACCCTAGATTTAGTCATCACTAACGCGATGATTATCGACTACACCGGGATT
TACAAAGCCGACATTGGGATTAAAAACGGCAAAATCCATGGCATTGGCAAGGCAGGAAACAAGGACATGCAAGATGGCGT
AAGCCCTCATATGGTCGTGGGTGTGGGCACAGAAGCACTAGCAGGGGAAGGTATGATTATTACCGCTGGGGGAATCGATT
CACACACCCACTTCCTTTCTCCACAACAATTCCCTACCGCTCTAGCCAATGGCGTTACAACCATGTTTGGAGGCGGCACA
GGTCCTGTAGATGGCACGAATGCGACTACTATCACTCCGGGCAAATGGAACTTGCACCGCATGTTGCGCGCAGCAGAAGA
GTATTCTATGAATGTGGGCTTTTTGGGCAAAGGCAATAGCTCTAGCAAAAAACAACTTGTAGAACAAGTAGAAGCGGGCG
CGATTGGTTTTAAATTGCATGAAGACTGGGGCACAACACCAAGTGCGATCGATCACTGCTTGAGCGTGGCAGATGAATAC
GATGTGCAAGTTTGTATCCACACCGATACAGTCAATGAGGCAGGTTATGTAGATGACACCCTAAATGCAATGAACGGGCG
CGCCATCCATGCCTACCACATTGAGGGAGCGGGTGGAGGACACTCACCTGATGTTATCACCATGGCAGGCGAGCTCAATA
TTCTACCCTCCTCCACCACCCCCACTATTCCCTATACCATTAATACGGTTGCAGAACACTTAGACATGCTCATGACATGC
CACCACCTAGACAAACGCATCCGCGAGGATTTACAATTTTCTCAAAGCCGTATCCGCCCCGGCTCTATCGCGGCTGAAGA
TGTGCTCCATGATATGGGTGTGATCGCGATGACAAGCTCGGATTCGCAAGCAATGGGGCGTGCAGGCGAAGTGATTCCTC
GAACTTGGCAGACTGCGGATAAGAATAAAAAAGAATTTGGTAAGCTTCCTGAAGATGGCAAAGATAACGATAATTTCCGC
ATTAAGCGCTACATCTCCAAATACACTATCAACCCCGCTTTGACCCACGGCGTGAGCGAGTATATCGGCTCTGTGGAAGA
GGGCAAGATCGCCGACTTGGTGGTGTGGAATCCTGCCTTTTTTGGCGTAAAACCCAAAATCGTGATCAAAGGCGGTATGG
TGGTCTTCTCTGAAATGGGCGATTCTAACGCGTCTGTGCCCACTCCCCAACCGGTTTATTACCGCGAAATGTTTGGGCAT
CACGGCAAGGCGAAATTTGACACCAGCATCACTTTTGTTTCCAAAGTCGCCTATGAAAATGGCGTGAAAGAAAAGCTGGG
CTTAGAGCGCCAAGTTCTACCGGTCAAAAACTGCCGTAACATCACCAAGAAAGACTTCAAGTTCAACGACAAAACGGCAA
AAATCACCGTCGATCCGAAAACCTTCGAGGTCTTTGTAGATGGCAAACTCTGCACCTCTAAACCCACCTCGCAAGTGCCT
CTAGCCCAGCGCTACACTTTCTTCTAG

Protein sequence :
MKMKKQEYVNTYGPTKGDKVRLGDTDLWAEVEHDYTTYGEELKFGAGKTIREGMGQSNSPDENTLDLVITNAMIIDYTGI
YKADIGIKNGKIHGIGKAGNKDMQDGVSPHMVVGVGTEALAGEGMIITAGGIDSHTHFLSPQQFPTALANGVTTMFGGGT
GPVDGTNATTITPGKWNLHRMLRAAEEYSMNVGFLGKGNSSSKKQLVEQVEAGAIGFKLHEDWGTTPSAIDHCLSVADEY
DVQVCIHTDTVNEAGYVDDTLNAMNGRAIHAYHIEGAGGGHSPDVITMAGELNILPSSTTPTIPYTINTVAEHLDMLMTC
HHLDKRIREDLQFSQSRIRPGSIAAEDVLHDMGVIAMTSSDSQAMGRAGEVIPRTWQTADKNKKEFGKLPEDGKDNDNFR
IKRYISKYTINPALTHGVSEYIGSVEEGKIADLVVWNPAFFGVKPKIVIKGGMVVFSEMGDSNASVPTPQPVYYREMFGH
HGKAKFDTSITFVSKVAYENGVKEKLGLERQVLPVKNCRNITKKDFKFNDKTAKITVDPKTFEVFVDGKLCTSKPTSQVP
LAQRYTFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 9e-150 59
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 9e-150 59
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-142 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-142 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-142 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-142 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB2 YP_004074031.1 urease subunit alpha VFG0270 Protein 0.0 74