Gene Information

Name : ureB (HFELIS_11980)
Accession : YP_004073872.1
Strain : Helicobacter felis ATCC 49179
Genome accession: NC_014810
Putative virulence/resistance : Virulence
Product : urease subunit B
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1179013 - 1180722 bp
Length : 1710 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAGATTTCACGAAAAGAATATGTTTCTATGTATGGTCCCACTACCGGGGATCGTGTTAGACTCGGCGACACTGA
TTTGATCTTAGAAGTGGAGCATGATTGCACCACTTATGGTGAAGAGATCAAATTTGGGGGCGGTAAAACTATCCGTGATG
GGATGAGTCAAACCAATAGCCCTAGCTCTTATGAATTAGATTTGGTGCTCACTAACGCCCTCATTGTGGACTATACGGGC
ATTTACAAAGCCGACATTGGGATTAAAGACGGCAAGATTGCAGGCATTGGCAAGGCAGGCAATAAGGACATGCAAGATGG
CGTAGATAATAATCTTTGCGTAGGTCCTGCTACAGAGGCTTTGGCAGCTGAGGGCTTGATTGTAACCGCTGGTGGCATCG
ATACGCATATTCACTTTATCTCTCCCCAACAAATCCCTACTGCTTTTGCCAGCGGGGTTACAACCATGATTGGAGGAGGC
ACAGGACCTGCGGATGGCACGAATGCGACCACCATCACTCCCGGACGCGCTAATCTAAAAAGTATGTTGCGTGCAGCCGA
AGAATACGCCATGAATCTAGGCTTTTTGGCTAAGGGGAATGTGTCTTACGAACCCTCTTTACGCGATCAGATTGAAGCAG
GGGCGATTGGTTTTAAAATCCACGAAGACTGGGGAAGCACACCTGCAGCTATTCACCACTGCCTCAATGTCGCCGATGAA
TACGATGTGCAAGTGGCTATCCACACCGATACCCTTAACGAGGCGGGCTGTGTAGAAGACACCCTAGAGGCGATTGCCGG
GCGCACCATCCATACCTTCCACACTGAAGGGGCTGGGGGTGGACACGCTCCAGATGTTATCAAAATGGCAGGGGAATTTA
ACATTCTACCCGCCTCTACTAACCCGACCATTCCTTTCACCAAAAACACTGAAGCCGAGCACATGGACATGTTAATGGTG
TGCCACCACTTGGATAAAAGTATCAAGGAAGATGTGCAGTTTGCCGATTCGAGGATTCGCCCCCAAACTATCGCGGCTGA
AGACCAACTCCATGACATGGGGATCTTTTCTATCACCAGCTCCGACTCTCAGGCTATGGGACGCGTAGGCGAGGTGATCA
CACGCACTTGGCAGACAGCAGACAAAAACAAAAAAGAGTTTGGGCGCTTGAAAGAGGAAAAAGGCGATAACGACAACTTC
CGCATCAAACGCTACATCTCTAAATACACCATCAACCCCGCGATCGCGCATGGGATTTCTGACTATGTGGGCTCTGTGGA
AGTGGGCAAATACGCCGACCTCGTGCTTTGGAGTCCGGCTTTCTTTGGCATTAAGCCCAATATGATTATTAAGGGCGGAT
TTATTGCGCTCTCTCAAATGGGCGATGCCAATGCGTCTATTCCCACCCCTCAGCCCGTCTATTACCGTGAAATGTTTGGA
CACCATGGGAAAAACAAATTCGACACCAATATCACTTTCGTGTCCCAAGCGGCTTACAAGGCAGGGATCAAAGAAGAACT
AGGGCTAGATCGCGTGGTATTGCCAGTGAAAAACTGTCGCAATATCACTAAAAAGGACCTCAAATTCAACGATGTGACCG
CACATATTGATGTCAACCCTGAAACCTATAAGGTGAAAGTGGATGGCAAAGAGGTAACCTCTAAAGCAGCAGATGAATTG
AGCCTAGCGCAACTTTATAATTTGTTCTAG

Protein sequence :
MKKISRKEYVSMYGPTTGDRVRLGDTDLILEVEHDCTTYGEEIKFGGGKTIRDGMSQTNSPSSYELDLVLTNALIVDYTG
IYKADIGIKDGKIAGIGKAGNKDMQDGVDNNLCVGPATEALAAEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRANLKSMLRAAEEYAMNLGFLAKGNVSYEPSLRDQIEAGAIGFKIHEDWGSTPAAIHHCLNVADE
YDVQVAIHTDTLNEAGCVEDTLEAIAGRTIHTFHTEGAGGGHAPDVIKMAGEFNILPASTNPTIPFTKNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDQLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYISKYTINPAIAHGISDYVGSVEVGKYADLVLWSPAFFGIKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFG
HHGKNKFDTNITFVSQAAYKAGIKEELGLDRVVLPVKNCRNITKKDLKFNDVTAHIDVNPETYKVKVDGKEVTSKAADEL
SLAQLYNLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-156 63
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-156 63
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-147 61
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-146 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-146 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-146 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_004073872.1 urease subunit B VFG0270 Protein 0.0 89