Gene Information

Name : Sulku_0649 (Sulku_0649)
Accession : YP_004059515.1
Strain : Sulfuricurvum kujiense DSM 16994
Genome accession: NC_014762
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 630392 - 631075 bp
Length : 684 bp
Strand : -
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: smd:Smed_5362 two component transcriptional regulator; PFAM: response regulator receiver; transcription

DNA sequence : 
ATGAAAGAGACCATTTTAATCATCGACGATGACAGTGCCATTCGTAAACTGCTCGAAGTCGCACTGGATGCGGCAGGGTA
TCACCCGGTAACAATTGCAACGGGAAAAGAGGGATTAAACCGCGCCGCGATCGAAGCCCCCGCATTAGTATTGCTTGATC
TTGGATTACCCGACATGGATGGGAAAGAGTTTCTCTCACAATTTCGTGAATGGAGCCAATCCCCCGTAATCGTCCTTTCT
GCCCGCTCCGGTGAGGCTGAAAAAATAGCAGCACTGGAGGGGGGATGTGATGATTATCTCACCAAACCCTTTGGGACAGG
TGAGCTACTAGCTCGTATCAAAGCTTCCCTCCGTCGTCGCGGTATCAGCATGGGAGATAATACTTCCGGTTTGATAAGCG
GTAATCTCTCGTTGGATATTGCTTCGCACACAGTGATGTTGAATAATGAAGAGTTAAAACTCACCCCCAAAGAGTTTGAC
CTCCTCAAAATCCTGATGCAAAACAGCGGCAAGGTTCTCACCCACGCATGGCTTCTCAAAGAGATTTGGGGAATCGGGTA
TCAAAACGAAACCCATTATCTACGCGTTTTTATCAATCAGCTCCGTCAAAAGATCGAAACCGATTCCACCCGTCCGAAAC
GGATTGTGACCGAAACAGGAATTGGGTATCGGTTTGTCGGATAG

Protein sequence : 
MKETILIIDDDSAIRKLLEVALDAAGYHPVTIATGKEGLNRAAIEAPALVLLDLGLPDMDGKEFLSQFREWSQSPVIVLS
ARSGEAEKIAALEGGCDDYLTKPFGTGELLARIKASLRRRGISMGDNTSGLISGNLSLDIASHTVMLNNEELKLTPKEFD
LLKILMQNSGKVLTHAWLLKEIWGIGYQNETHYLRVFINQLRQKIETDSTRPKRIVTETGIGYRFVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kdpE NP_370594.1 transcriptional regulator kdpE Not tested Type-II SCCmec Protein 6e-39 43
kdpE NP_373306.1 hypothetical protein Not tested Type-II SCCmec Protein 6e-39 43
kdeP YP_190033.1 DNA-binding response regulator KdeP Not tested Type-II SCCmec Protein 6e-39 43
SH0031 YP_251946.1 hypothetical protein Not tested SCCmec Protein 9e-40 43
kdpE BAA82188.1 KDP operon transcriptional regulatory protein KdpE Not tested Type-II SCCmec Protein 4e-39 43
kdpE YP_039536.1 response regulator protein Not tested Type-II SCCmec Protein 6e-39 43
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-29 41
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 3e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sulku_0649 YP_004059515.1 winged helix family two component transcriptional regulator NC_012469.1.7686381. Protein 2e-35 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sulku_0649 YP_004059515.1 winged helix family two component transcriptional regulator VFG1563 Protein 1e-29 41
Sulku_0649 YP_004059515.1 winged helix family two component transcriptional regulator VFG1702 Protein 1e-29 41