Gene Information

Name : Sulku_2379 (Sulku_2379)
Accession : YP_004061239.1
Strain : Sulfuricurvum kujiense DSM 16994
Genome accession: NC_014762
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2392449 - 2393696 bp
Length : 1248 bp
Strand : +
Note : COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: abu:Abu_0661 UDP-hexose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation

DNA sequence :
ATGAAAATTGCAATTATCGGATTGGGATATGTTGGATTGCCGTTAGCACACGCTTTTTCAGAAAAATATTCTGTTGTAGG
TTTTGATATTAATCAAACACGTATCGATGAACTTAAAAGTGGATATGATCGAACATTGGAACTTAATTCCTCTCAGTTGC
AAGAAGCTTTTGAAAGAGATCTATATTTAACCACATCCATTGATGATATTAAAGATTGCACAATTTTTATCATAACCGTT
CCAACTCCAATCGATCATTATAAAAAACCCAACTTGACTCCCTTGTTAAAAGCCACGGAAACTGTCGGAAAGTTACTAAA
AAGAAATGATATCGTTATTTATGAGAGTACGGTTTACCCCGGATGTACCGAGGAAGATTGCGTACCAATTCTTGAAAAAA
CTTCCGGATTAAAATTCAATCACGATTTTTTTTGCGGCTACTCGCCTGAACGAATTAATCCGGGGGATAAAGAGCATACC
GTTACCAAAATTCTTAAAGTTACAAGCGGAAGTACACCAGAAATCGGAGAAAGAATCAACAACTTGTATGCAAGTGTGAT
CACTGCCGGGACGCATTTAGCGCCGACCATAAAAGTTGCCGAAGCCGCAAAGGTTATTGAAAATGCTCAACGGGACGTCA
ATATCTCATTTGTCAATGAGCTTGCAGTCATGTTTGATAAAATGGGGATTGATACACAAGATGTGTTGGCCGCAGCTGGA
ACAAAATGGAATTTTTTAAAATTCAAACCAGGTCTTGTCGGCGGCCACTGCATTGGAGTGGATCCATATTATCTCGTTCA
TAAAGCGGAAAGTATCGGCTATTTCCCACAGGTCATCTTATCTGGGCGACGAATTAATGAAAACATGGGTATTTTTGTAG
CCAATAAAGTTATAAAACTAATGATCAAAAAAGGGCTCAAAATTGAAGGCTCAAAAGTATTAGTCTTGGGGATAACCTTT
AAAGAGAATTGTCCGGATATCCGTAATAGCAGGGTTGTAGACGTTGTAGAAGAATTACGTGAATTTGGTTGTATTGTAGA
TATCAGCGATCCATGGGCAAATGCAAAAGAAGTTAAAGAGGAATACAATTTTAATTTACTTGATCATCAAAAATTAGAAT
TAGATGCTTATGATGCCATTATCCTAGCTGTTGCACATAACGAATACAAAACGATCCCCCTTCAAAACACCAATCAAGTC
ATTTTTGATATTAAAGGAGTTTTGGACAAAGCAGATGGAAGATTGTAA

Protein sequence :
MKIAIIGLGYVGLPLAHAFSEKYSVVGFDINQTRIDELKSGYDRTLELNSSQLQEAFERDLYLTTSIDDIKDCTIFIITV
PTPIDHYKKPNLTPLLKATETVGKLLKRNDIVIYESTVYPGCTEEDCVPILEKTSGLKFNHDFFCGYSPERINPGDKEHT
VTKILKVTSGSTPEIGERINNLYASVITAGTHLAPTIKVAEAAKVIENAQRDVNISFVNELAVMFDKMGIDTQDVLAAAG
TKWNFLKFKPGLVGGHCIGVDPYYLVHKAESIGYFPQVILSGRRINENMGIFVANKVIKLMIKKGLKIEGSKVLVLGITF
KENCPDIRNSRVVDVVEELREFGCIVDISDPWANAKEVKEEYNFNLLDHQKLELDAYDAIILAVAHNEYKTIPLQNTNQV
IFDIKGVLDKADGRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-121 58
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-121 58
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-111 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sulku_2379 YP_004061239.1 nucleotide sugar dehydrogenase VFG0431 Protein 4e-122 58