Gene Information

Name : Ocepr_0552 (Ocepr_0552)
Accession : YP_004057183.1
Strain : Oceanithermus profundus DSM 14977
Genome accession: NC_014761
Putative virulence/resistance : Resistance
Product : heavy metal translocating p-type atpase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 553934 - 556093 bp
Length : 2160 bp
Strand : +
Note : COGs: COG2217 Cation transport ATPase; InterProIPR006403: IPR006416: IPR001757: IPR008250: IPR 005834: IPR001756: IPR018303; KEGG: ttj:TTHA1733 copper-transporting ATPase, P-type (CopB); PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase

DNA sequence :
ATGAAGGACCACAAACACGACGACGCGGCGCATGCGGCGCACGAGAAGCACGCGCACGCGCAGCACAAAGACGAACCCGC
CGGCCACGAAGGTCACGAAGGCCATGGCGAGGCGGGCCACGACGGGCACGCCGGGCACGAAGGCCACGGCGCTCGGTCCG
GCCACGAGGGCCACGGCGAGCACGACGGCCACGGCGGGCACGACAAGCACGCGGGGCACGACCCCGAGATGTTCCGCCGC
CGGTTCTGGCTGAGCCTGGCGCTCACCGTCCCCATCCTCTACTTCTCCCCGCAGCTGCAGGCCTGGCTGGGTTACACCGC
CTGGGACGTGGCCTGGGGGCGCTGGGTCGGCCCGGTGCTGGGTTCGATCCTCTACTTCTACGGCGGGGGCCCCTTCCTCG
AGGGGGCGGTGCGCGAGTTCCGCCACCGCGTCCCGGGGATGATGAGCCTGATCGCCCTGGCCATCAGCGTGGCCTACGCC
TACAGCCTGGCGGTCTCCTTTGGCTTCCCCGGCAAACCCTTCTACTGGGAGCTCGCGACGCTGATCGACGTGATGCTGCT
CGGCCACTGGATCGAGATGAAGAGCGTGCAGCAGGCCCAGGGGGCGCTCGAGGCGCTGGCCAAGCTGATGCCCACCACCG
CGCACCGGGTGGTGGGGGAGAAGGTCGAGGACGTCCCGGTGAGCGAGCTGCGCGAGGGCGACGTCATCATGGTGCTGCCC
GGGGAGCAGGTGCCCGCCGACGGCGTCATCGTCTCGGGGCGCACGACGCTGAACGAGGCCTTCCTCACCGGCGAGTCGAA
GCCGGTGGAGAAGCAGGCGGGCGACGAGGTGGTCGCCGCCGCCATCAACAACGACGGTGTGATCCAGGTGAAGGTGACCC
GCACCGGCGAGGCCACCACCCTCTCCCAGATCATGCGCTTGGTCAAGGAGGCGCAGCAGGCGCGCAGCCGTTTCCAGGCC
CTCGCCGACCGCGCCGCTTCGTGGCTCTTCTACGTCGCCGTCGTGGTGGGCGGCGGGGCCTTCGGGGTCTGGCTCGCCCT
GGGGCAGCCGTTCGACTTCGCCCTGGGCGTTGCCGTGACCACGCTGGTCATCGCCTGCCCCCACGCGCTGGGTCTGGCCA
TCCCGCTGGTCAACGTCAACGCCACCGCGCTGGCTGCCAAGAACGGCGTGCTGGTGCGCAACCGCGAGGCCTTCGAGCGC
GCCCGCGACATCCGCGTCGTGGCCTTCGACAAGACCGGCACCCTCACCGAAGGCCGCTTCGCGGTGAGCCGGGTGGCCGC
GGCCGCGATCACGGAGGACGAGCTGCTGGCCCTGGCGGCCGCGATCGAGCGGCAGAGCTCCCACCCGCTCGCCGACGCGA
TCGTCGAGGCCGCCGAGGAGCGCGGCGTCCAACTGCCCGCGGCCGTTGAGGTCCAGGCCGTCCCCGGACAGGGCGTCGTG
GGCACGATCGACGGCCGCAAGGTCTACGTGGGCCGGCCCGAGTGGACCGACGAGTTCGGGCTCGCGCTCGATCCGGTGCG
CGCGGCCGTGACCACCGCCGAGGAGCGCGGCGAGAGCCTGATCGTCGTCTTCGAGGAGGGGCGCGTCCTCGGGGCGCTGG
CGCTCGCGGACCGGGTGCGCGACAGCGCCCGCACCGCGGTGGCCCGTCTGCTCGAGATGGGCGTGGAGCCGGTGATGATC
ACCGGCGACGCCGAGGCCGTGGCCCGCACCGTCGCGGGGGACCTGGGCATCCGCCGCTACTACGCCCGCGTCATGCCCCA
GGACAAGGCGCGCATCGTCCGCGAGCTCAAGCAGCTCGGCCACGTCGCCTTCGTGGGGGACGGCATCAACGACGCCCCCG
CGCTGGTGGAGGCCGATCTGGGCGTCGCCATCGGCGCCGGAACCAACGTGGCCATCGAGTCGGCGGACCTGGTCCTGGTG
GAGAACGACCCCCTCGACGTGGTGCTGGCGCTCAAGCTGGCCCGCGCCACCTACCGCAAGATGGTCGAGAACCTCGTCTG
GGCCACGGGGTACAACGTGGTGGCCATCCCGCTGGCGGCCGGCGTGGCCTACGGCTGGGGCATCCTACTCAACCCGGCCG
TGGGGGCGATCTTCATGAGCCTCTCGACCGTGGTCGTTTCGCTCAACGCCATCGCCCTGCGCCGGGCCAAGCTGGCCTGA

Protein sequence :
MKDHKHDDAAHAAHEKHAHAQHKDEPAGHEGHEGHGEAGHDGHAGHEGHGARSGHEGHGEHDGHGGHDKHAGHDPEMFRR
RFWLSLALTVPILYFSPQLQAWLGYTAWDVAWGRWVGPVLGSILYFYGGGPFLEGAVREFRHRVPGMMSLIALAISVAYA
YSLAVSFGFPGKPFYWELATLIDVMLLGHWIEMKSVQQAQGALEALAKLMPTTAHRVVGEKVEDVPVSELREGDVIMVLP
GEQVPADGVIVSGRTTLNEAFLTGESKPVEKQAGDEVVAAAINNDGVIQVKVTRTGEATTLSQIMRLVKEAQQARSRFQA
LADRAASWLFYVAVVVGGGAFGVWLALGQPFDFALGVAVTTLVIACPHALGLAIPLVNVNATALAAKNGVLVRNREAFER
ARDIRVVAFDKTGTLTEGRFAVSRVAAAAITEDELLALAAAIERQSSHPLADAIVEAAEERGVQLPAAVEVQAVPGQGVV
GTIDGRKVYVGRPEWTDEFGLALDPVRAAVTTAEERGESLIVVFEEGRVLGALALADRVRDSARTAVARLLEMGVEPVMI
TGDAEAVARTVAGDLGIRRYYARVMPQDKARIVRELKQLGHVAFVGDGINDAPALVEADLGVAIGAGTNVAIESADLVLV
ENDPLDVVLALKLARATYRKMVENLVWATGYNVVAIPLAAGVAYGWGILLNPAVGAIFMSLSTVVVSLNAIALRRAKLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 7e-84 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ocepr_0552 YP_004057183.1 heavy metal translocating p-type atpase BAC0629 Protein 3e-139 53
Ocepr_0552 YP_004057183.1 heavy metal translocating p-type atpase BAC0079 Protein 2e-112 44
Ocepr_0552 YP_004057183.1 heavy metal translocating p-type atpase BAC0383 Protein 8e-103 43
Ocepr_0552 YP_004057183.1 heavy metal translocating p-type atpase BAC0101 Protein 2e-79 42