Gene Information

Name : Ocepr_0477 (Ocepr_0477)
Accession : YP_004057109.1
Strain : Oceanithermus profundus DSM 14977
Genome accession: NC_014761
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 478185 - 479783 bp
Length : 1599 bp
Strand : +
Note : COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR011796: IPR006121: IPR013027: IPR004099: IPR 000815: IPR012999: IPR017969; KEGG: ttj:TTHA1153 mercuric reductase; PFAM: FAD-dependent pyridine nucl

DNA sequence :
ATGATCCGACTTAAGCTCTTCGGCATGACCTGCGCGGGTTGCGCCGAGGCCGTGGGCCGGGCGCTCGAGGCCGTGCCCGG
GGTGCGCAAGGTGGCCGTCGACTACGAGGCGGCGCGGGCCGAGGTCTGGGGCGACGCCGACCCCGGGGACCTGATCGCCG
CAGTGCGGGCGGCCGGCTACGAGGCCCGGTTGGAAGAAGCGGGCGGACCGGCGGCGGCCGTGAAAAACGAGTCCACGAGC
CCCGACCTGGTGGTGATCGGCAGCGGTTCGGCGGGGGTGGCGGCGGCGCTGGAGGCCGCGGGTCGGGGCGCGCGGGTGTG
GGTCGTCGAGTCCGGCACCCTGGGCGGGACCTGCGTCAACGTGGGCTGCGTACCCTCCAAGACGCTGCTCAGGGCCGGCG
AGGCCGCCGAGCGGGCCCGCAACGCAGGCTTTCCCGGCGTCGAAGCCCGGGGGGCGGAGGTGGACTTCGCGGGGGTGGCC
CGCGCGCGCGACGCGCTGGTAAGCGATCTGCGCAAGCGCAAGTACCGCGAGGTGCTCGAGGCCGCGGGGGTGGTCCTCAA
GCAGGGGCACGCCCGCTTCACCGCGCCCGACCGCCTGGAGGTGGACGGCGAACCGGTCGCCGCCCACGCCTACCTGGTGG
CCACCGGTGCGGAGCCGGTTCTGCCCACCGTTCCCGGGCTGGAGGGGGGCCGGATCTGGACCTACCTGGACGCCACCACC
GCCCGCGAACGCCCCGAAAGTCTGGTCGTCGTCGGCGCCGGTGCGGTTGGGCTGGAGCTGGCCCAGGCCTACCGGCGGCT
GGGGAGCCGGATCGTCGTCCTTGAAGCCCAAGACCGCATCCTGCCGGGCGAGGACGAGGAACTGACCACCCTGCTGCGGG
GCTACCTGGAAAAGGAAGGCCTGCAGGTCGTTACCGGAGTCCGGGTGGAGCGGATCGAGGGGGGAGAGGTGCGCACGACC
GGGGGAGTCTACGAGGGCGAGCGGGTGCTCGTGGCCACCGGCCGCCGCGCGCGCACCCGGGGGCTGGGGCTCGAGGCCGC
CGGCGTCGAGCTCGACGCCGGCGGCTTTGTCCGCGTGGACACGGCCCTCCGCACCTCCAATCCGCACGTCTTTGCCGCGG
GTGACGTGGCGGGCTTGCCCCAGTTCGTCTACGTCGCGGCCCAGTCGGGGAGGGTGGCGGCGCAGAACGCCCTGGGGGCG
GGCGCCACCCTCGACCTCGCCGCCGTTCCCCGCGTCACCTTCACCGACCCGGCGCTCGCCGCCGTGGGCCTGAGCGAGGC
CGAAGCGCGGGCGCGGTACGGCGAGGGTGTTCGCACCGCGACCCTCGACCTGGCCGACCTGCCCCGGGCGCTGGCCGCCT
TCGACACCCGCGGTCGCTTCAAGATCGTCGTGGACGCAGAGGGCCGGGTGCTGGGGCTGCAGCTGCTGGCGCCGGAAGCG
GGCGACATGATTGCCGAGGGGGCGCTGGCCGTGCGCCTGGGGCTCGGCTACCGCGAGCTGATCGAGACCTACCACCCCTA
CCTGACCCTTGCCGAGGGGGTTCGGTTGGTCGCCCAAGCCCTGGACACCGACGTCAAACGGCTTTCTTGCTGCGCCTAG

Protein sequence :
MIRLKLFGMTCAGCAEAVGRALEAVPGVRKVAVDYEAARAEVWGDADPGDLIAAVRAAGYEARLEEAGGPAAAVKNESTS
PDLVVIGSGSAGVAAALEAAGRGARVWVVESGTLGGTCVNVGCVPSKTLLRAGEAAERARNAGFPGVEARGAEVDFAGVA
RARDALVSDLRKRKYREVLEAAGVVLKQGHARFTAPDRLEVDGEPVAAHAYLVATGAEPVLPTVPGLEGGRIWTYLDATT
ARERPESLVVVGAGAVGLELAQAYRRLGSRIVVLEAQDRILPGEDEELTTLLRGYLEKEGLQVVTGVRVERIEGGEVRTT
GGVYEGERVLVATGRRARTRGLGLEAAGVELDAGGFVRVDTALRTSNPHVFAAGDVAGLPQFVYVAAQSGRVAAQNALGA
GATLDLAAVPRVTFTDPALAAVGLSEAEARARYGEGVRTATLDLADLPRALAAFDTRGRFKIVVDAEGRVLGLQLLAPEA
GDMIAEGALAVRLGLGYRELIETYHPYLTLAEGVRLVAQALDTDVKRLSCCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 2e-51 42
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 9e-55 42
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 3e-51 42
merA AGK07021.1 MerA Not tested SGI1 Protein 1e-53 41
merA AGK07079.1 MerA Not tested SGI1 Protein 1e-53 41
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 8e-52 41
merA ABQ57371.1 MerA Not tested SGI1 Protein 1e-53 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ocepr_0477 YP_004057109.1 mercuric reductase BAC0653 Protein 1e-51 42
Ocepr_0477 YP_004057109.1 mercuric reductase BAC0652 Protein 5e-54 41