Gene Information

Name : Ocepr_0004 (Ocepr_0004)
Accession : YP_004056643.1
Strain : Oceanithermus profundus DSM 14977
Genome accession: NC_014761
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 4013 - 5440 bp
Length : 1428 bp
Strand : +
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR001697; KEGG: ttj:TTHA0003 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate

DNA sequence :
ATGCTTTCTAAGCGCACCAAGATCGTCGCCACCATCGGGCCCGCCTCGCGCGACCCCGAGGTGCTCGCCCGCATGATCCA
GGCGGGGCTCAACGTGGTGCGGCTCAACTTCAGCCACGGCCGCCCCGAGGACCACCGCGAGACCGTCGAGATGGTGCGCG
CCGCCGCGGAGCACGCCGCCCGCCCCGTCGCCATCCTGCAGGACCTGCAGGGGCCCAAGATCCGCGTCGGCCGTTTCGCC
GAGGGGAAGGCGGTGCTGAAGGCGGGCCAGCCCTTCGTGCTCACCACCGCCGACGTCACCGGCGACGAGCACCGGGTCTC
GGTGAGCTACAAGGGGCTGGTGGGCGACGTCGAGCCCGGCCAGGTGCTGCTGCTCGACGACGGGCGGCTGCGCCTGCGGG
TGGACCGGGTCGACCACGCGGCGGGCGAGATCCACACCGTCGTCGAGGTGGGGGGCGTGCTCTCGGACCAGAAGGGGATC
AACATCCCCGGGGCCGACCTCTCGATCCCGGCGATGACCGACAAGGACATCGAGGACCTGGCGCTGGGGGCCGAGCTGGG
GGTGGACTGGGTCGCGGTCAGCTTCGTGCGCAGCCGCGACGACCTGCTGCTCGCCCGCCACTACATGAACCGCCTGGGCC
ACGAGGCCAAGCTGATGGCCAAGATCGAGAAACCGGGGGCGGTGCAGCGCTTCGACGAGATCCTGGCCGAGGCCGACGGC
GTCATGGTCGCCCGCGGCGACCTCGGGGTGGAGATGCCCCCCGAGGAGGTGCCCATCGTGCAGAAGCGGCTGATCCGGCG
CACCCGCGCCGCCGGCAAGCCGGTGGTCACGGCCACGCAGATGCTCGAGTCCATGATTCACAGCCCCAGCCCCACGCGCG
CCGAGGCCTCGGACGTGGCCAACGCCATCTTCGACGGCTCCGACGCGGTGATGCTCTCGGCCGAGACCGCGGTGGGGGAG
TACCCGGTCGAGGCCGTGGCCATGATGGCGCGGGTGGCCCGCGCCGTCGAGGGTTCCCCGGAGTACCAGAACGCCCAGCG
GATCCTGCGGCCCGAGCCCGAACACAACACCCAGGACGCGATCGCGCTCGCGGCCACCGAGGTCGCCGAGTCGCTGCCGG
CCAAGGTGATCGTCGTCTTCACGGCGTCGGGCTCCTCGCTGTGGCGGGTGGCCCGCTACCGCCCCGGGGTGCCCATCCTG
GCGCTCACCCCCAACGCCCGGGTGCGCCAGCAGCTGGTGCTGGCCTCGGGGGTCTACACGGCCACCGCCCCCGACCCGAC
GAGCACCGACGAGATGGTCGCCGAGGCCGTCGACTTCGTCAAGAGCGCGAAGCTGGCCGACGTGGGCGACCGCATCGTCA
TCACCGCGGGGGTGCCCTTCGGCGTCCGCGGTTCGACGAACATGGTCTGGGTGGAACAGGTGAAGTAA

Protein sequence :
MLSKRTKIVATIGPASRDPEVLARMIQAGLNVVRLNFSHGRPEDHRETVEMVRAAAEHAARPVAILQDLQGPKIRVGRFA
EGKAVLKAGQPFVLTTADVTGDEHRVSVSYKGLVGDVEPGQVLLLDDGRLRLRVDRVDHAAGEIHTVVEVGGVLSDQKGI
NIPGADLSIPAMTDKDIEDLALGAELGVDWVAVSFVRSRDDLLLARHYMNRLGHEAKLMAKIEKPGAVQRFDEILAEADG
VMVARGDLGVEMPPEEVPIVQKRLIRRTRAAGKPVVTATQMLESMIHSPSPTRAEASDVANAIFDGSDAVMLSAETAVGE
YPVEAVAMMARVARAVEGSPEYQNAQRILRPEPEHNTQDAIALAATEVAESLPAKVIVVFTASGSSLWRVARYRPGVPIL
ALTPNARVRQQLVLASGVYTATAPDPTSTDEMVAEAVDFVKSAKLADVGDRIVITAGVPFGVRGSTNMVWVEQVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-68 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-68 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 43
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 8e-58 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ocepr_0004 YP_004056643.1 pyruvate kinase VFG0479 Protein 1e-68 43