Gene Information

Name : pykA (NLA_0420)
Accession : YP_004047682.1
Strain : Neisseria lactamica 020-06
Genome accession: NC_014752
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 52206 - 53678 bp
Length : 1473 bp
Strand : -
Note : -

DNA sequence :
ATGAACCAGACAAGCCGCGATCTGACCCGCATCAGCCACAACACCAAAATCGTCGCCACCCTTGGGCCGGGCAGCAACAA
CGTCGAACTGTTGGAAGATATGATCCGCGTCGGCGGCCTGAACGTCGTCCGCTTCAACTTCAGCCACGGCACGCCCGAAT
TCCATCAGGAAAACGCCCGCATCGTGCGCGAGGCGGCAAAACGCGCCGGACAGGAAATCGCCATCATTGCCGACCTGCAA
GGGCCGAAAATCCGCGTGGGCAAAATCGCCGGCGGCGGCATCGAATTGAACAAAGGCGAAACGCTGGTACTGGATGCCGC
GCTCGAAGGCGAAGGCACGCGCGAGGCGGTCGGTTTGGACTACCGCGACCTGCCCGACGACGTTGCCGCAGGCGATGTCT
TGTGGCTGGACGACGGCCTGCTGACCCTGACCGTGGAATCCGTCGAAGGCAGCAGGATTATCACAAGGGTGGAAAACAGC
CACGTCCTGAAAAGCAACAAGGGCATCAACAAACGCGGCGGCGGTCTGTCCGCAGGCGCGTTGACCGAAAAAGACTTCCG
CGACCTGAAAACCGCGATTGCCATCGGTTGCGACTACCTCGCCATCAGCTTTGTGAAATCTGCCGAAGATTTGCACATCG
CGCGCGCCAAAGTCGAAGAAGAAATGAAGGGCAGCACTGCCGTGCGCCCCGGTTTGGTTTCCAAAATCGAACGCGTAGAA
GCGATTGAAAACCTTGATGAAATCATCCTCGCCGGCGACGGCATTATGGTTGCGCGCGGCGACTTGGCGGTCGAAGTCGG
ACACGCCGCCGTCCCCGCCCTGCAAAAACGGATGATCCGCCGCGCCCGCGAGTTGCGCCGCTTCAGCATTACGGCGACGC
AAATGATGGAATCGATGATTACCAACCCCGTGCCGACCCGCGCGGAAGTCAGCGATGTGGCAAACGCGGTATTGGACGGT
ACCGATGCGGTGATGTGTTCCGCCGAAACCGCCGTCGGCGCGTATCCGTTTGAAACCGTCAGCCAAATGGCAATTATCTG
CGCGGCTGCGGAAAAAGAGCAGGATTCGCTCAACGGCGTTGCCGAACAGGCGGAGTATCCCGAAGCGGTCAGCACCAACC
TGGCGGTTGCCGGCGGCGCGGTCAGCGTGGCGCGCGCGGTTCACGCCAAAGCGATTGTCGCCCTGACCGAAAGCGGTTCG
ACCGCCTTTGAAATCAGCCGCCACAACATCACCCTGCCGATTTTCGCGCTGACCCCGAGCGTTTCCGCCCAACGCCGTAT
GGCGATGTACCGGGGCGTGCGCCCGCTGATTTTGGCAACCAGTACCGACCACGACACGGCGTTGAACGAAGTCGAAACGA
TGCTGGTGGAACACAACATCCTGCATTCCGGCGACCAGTACATCATCACCAGCGGTTCGCAAATGCGCGAATCCGGTTCG
ACCAACACACTGGAAGTGCTGCACGTCAAATAA

Protein sequence :
MNQTSRDLTRISHNTKIVATLGPGSNNVELLEDMIRVGGLNVVRFNFSHGTPEFHQENARIVREAAKRAGQEIAIIADLQ
GPKIRVGKIAGGGIELNKGETLVLDAALEGEGTREAVGLDYRDLPDDVAAGDVLWLDDGLLTLTVESVEGSRIITRVENS
HVLKSNKGINKRGGGLSAGALTEKDFRDLKTAIAIGCDYLAISFVKSAEDLHIARAKVEEEMKGSTAVRPGLVSKIERVE
AIENLDEIILAGDGIMVARGDLAVEVGHAAVPALQKRMIRRARELRRFSITATQMMESMITNPVPTRAEVSDVANAVLDG
TDAVMCSAETAVGAYPFETVSQMAIICAAAEKEQDSLNGVAEQAEYPEAVSTNLAVAGGAVSVARAVHAKAIVALTESGS
TAFEISRHNITLPIFALTPSVSAQRRMAMYRGVRPLILATSTDHDTALNEVETMLVEHNILHSGDQYIITSGSQMRESGS
TNTLEVLHVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 0.0 99
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-53 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_004047682.1 pyruvate kinase VFG0479 Protein 1e-53 42