Gene Information

Name : pyk (MSB_A0269)
Accession : YP_004047026.1
Strain : Mycoplasma leachii PG50
Genome accession: NC_014751
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 313425 - 314861 bp
Length : 1437 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM TIGR01064

DNA sequence :
ATGACTAAAGAAACATTACAAAAGAGAATGAAACGAACCAAAGTAATTACAACAATTGGTCCTTCAACTCACTCTGCAGA
AGCTATTAAAGAATTATTTAGCAATGGTATGACAACTATTCGTTTAAATTTTTCACATGGTAGTTATGAAGAACACGGTT
ATAGAATTAAAGCTGCAAAAAAAATCTCTAAAGCTTTAAATAAGCCAATCTCAATAATGTTAGATACTAAAGGTCCTGAA
ATAAGATTAGGAAAATTTAAAGATAATAAACAAGAAGTAGTAAAAGGTCAAGCAATTACTATTTATACAGATAGTTATTC
TTATTTAAACAAAGAATGTGTTCAAGGTGAAATGACTGTTGCTTATGATATGTCAGTTGATTTAAAACCTGGAGATATGA
TTTTAATTGATGATGGTAAATTAGAATTAACAGTTGATTCAGTTGAACCTCAAATTATTAAAGCAACTGCATTTAATCAT
CACATTGTAAAAACTAATAAACGTGTTAACTTACCTGGAATTGATTTTTCATTACCATTTTTATCTGAAAAAGATGAAAA
AGATATTTTATTTGGATGTGAACAAGGTGTTGATTATATAGCTGCATCATTTGTAAATACAGCTGAAAATGTAAGACAAA
TTAAAGAAATCTTAACTAAAGCTAATGCAAATCATATTCAAATTATTTCAAAAATAGAATCACAAGTTGGATTAGATAAT
ATTGATGAAATTATTGAAGAATCTGATGGAATTATGATTGCGCGTGGTGATTTAGGATTAGAAATTCCATATTATGATGT
ACCTTATTGAGAAAAAATTATCATCAGAAAATGTAGAGAAAAAGGAAAAATCGTTATTGTTGCTACTCAAATGTTAGAAA
CAATGACAGAAAATCCATCACCAACTAGAGCTGAAGTAACTGATGTTTATTATGCAACTGAACTTGGTGCTGATGCTACA
ATGTTATCTGGTGAATCAGCTGCTGGAGATTATCCATTTTTAACAGTTCATACAATGTCAACAATTAATAAAAGAGCAGA
AGTTGAATTCTACAACAAAATTTACTACCAAGTACAATTAGATAATGCAAGAAACTCAACATCAGGACCTAGAGCTGAAA
TTGCAGACTTATTAGCTACAAAAACAAAAGATGGTGAATATAAGTATGCTATTGTTTTATCAAAAACAGGTGAATTATTA
AAAACCATTTCTAAATTTAGACCAAATGTAACAATTTTAGGAGTTAGTCCAGATAAGAAATTGTGAACTTCATTTGGTGT
ATGACATTCAATTTTTATGAATAAAGTTGATACTTTAGATAATTTAGATAATAATGTTGAAAAACTATCAGAAATTGCTA
AGTCTTGAGGAGCTAAGCTTGGTGAAAAAGTTTTAGTTGTAAGAAGTACAGCTATAAAAGAAATAGAAGTTATTTAA

Protein sequence :
MTKETLQKRMKRTKVITTIGPSTHSAEAIKELFSNGMTTIRLNFSHGSYEEHGYRIKAAKKISKALNKPISIMLDTKGPE
IRLGKFKDNKQEVVKGQAITIYTDSYSYLNKECVQGEMTVAYDMSVDLKPGDMILIDDGKLELTVDSVEPQIIKATAFNH
HIVKTNKRVNLPGIDFSLPFLSEKDEKDILFGCEQGVDYIAASFVNTAENVRQIKEILTKANANHIQIISKIESQVGLDN
IDEIIEESDGIMIARGDLGLEIPYYDVPYWEKIIIRKCREKGKIVIVATQMLETMTENPSPTRAEVTDVYYATELGADAT
MLSGESAAGDYPFLTVHTMSTINKRAEVEFYNKIYYQVQLDNARNSTSGPRAEIADLLATKTKDGEYKYAIVLSKTGELL
KTISKFRPNVTILGVSPDKKLWTSFGVWHSIFMNKVDTLDNLDNNVEKLSEIAKSWGAKLGEKVLVVRSTAIKEIEVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-72 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-72 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-72 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_004047026.1 pyruvate kinase VFG0479 Protein 3e-72 41