Gene Information

Name : Hbor_03110 (Hbor_03110)
Accession : YP_004035360.1
Strain : Halogeometricum borinquense DSM 11551
Genome accession: NC_014729
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 294765 - 295967 bp
Length : 1203 bp
Strand : +
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence :
ATGAATGATTCTGATTACCAGTTTGAAACACTCGCGGTGACGCACGGCGAACGTCAACGTCCTGCCGAGGGTGTCGAGGA
CGTGGCTGTGCCCGTCCACCTCGCCTCGACGTTCGCGGTGCCCGAGATCGACCCCGATGCGTCGCTGGAGTCGCTCGATC
CCGACGCGGGCGAGTATCTCTACTCACGTCTCTCGAACCCGACGCGGAATGCGCTCGAACACCGTATCGCCGCGCTCTGT
GGGGGCGATCACGCACTCGCATTCGCCTCGGGAACCGCAGCCATCGTGACCGCTATCTCGGCCGCCGTCCAACCCGGCGA
CCACATCGTCGCCTTCGATGACCTGTACGGCGGTACGAAGTCGATGCTCTCCGATCTTTTCGAGGATCGACTGAACGTCA
GCGTCTCGCTCGTCGATGCGCGCGACACCGACACTGTCGCTGCCGCGATGCGCGAGGAGACATCGCTCGTCTGGATGGAG
ACGCCGACGAATCCGCTTCTCAGACTCTGTGACATCGAGGCTATCGCCGCTATCGCCGACGAATACGGAGCGACGTTCGG
CGTAGACAACACGTTCGTCGGCCCGCACTTCCAGCGACCGCTCGAACTCGGCGCGGACGTGGTCGTCCACTCGACGACGA
AGTACCTGAACGGTCACTCCGATTCTATCGGTGGGGCGCTGGCGACGAACGACGAGGCGTACGCCGAGGAAATGACGTTC
CTCCAGCGCGTCGGGATGGGGAACATGCTCGCGCCGTTCGACGCGTACCTCACTCTGCGCGGACTGAAGACGCTCCCGCT
TCGGATGGAGAAACACGCCTCGAACGCGCAGGCTGTTGCGGAGTTCCTCGCAGACCACCCAGCGGTCGAAGCGGTCCACT
ATCCGGGACTAGAATCACACCCGCAACACGACCTCGCCTCCCGGCAGATGTCGGGCTACGGCGGCGTCCTCTCTATCGAA
CTGGATACGGATTTAGACGGCGTCGCACGGTTCGTCGCCGCACTTGAACACTTCCCGCTGGCGGTCAGTCTCGGCGGCGT
CGAGTCGCTCATCGAACATCCGGCCTCGATGACCCACTCACCGCTCTCGCAGGAAGAACGGGACATGCTCGGAATCACCG
ATAGTCTCCTGCGTCTCTCTGTCGGCGTCGAACACGAAGCAGACTTGCTCTCGGACCTTTCGGACGCCCTCGACGTTATC
TGA

Protein sequence :
MNDSDYQFETLAVTHGERQRPAEGVEDVAVPVHLASTFAVPEIDPDASLESLDPDAGEYLYSRLSNPTRNALEHRIAALC
GGDHALAFASGTAAIVTAISAAVQPGDHIVAFDDLYGGTKSMLSDLFEDRLNVSVSLVDARDTDTVAAAMREETSLVWME
TPTNPLLRLCDIEAIAAIADEYGATFGVDNTFVGPHFQRPLELGADVVVHSTTKYLNGHSDSIGGALATNDEAYAEEMTF
LQRVGMGNMLAPFDAYLTLRGLKTLPLRMEKHASNAQAVAEFLADHPAVEAVHYPGLESHPQHDLASRQMSGYGGVLSIE
LDTDLDGVARFVAALEHFPLAVSLGGVESLIEHPASMTHSPLSQEERDMLGITDSLLRLSVGVEHEADLLSDLSDALDVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-46 45
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-50 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-51 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hbor_03110 YP_004035360.1 cystathionine gamma-synthase BAC0207 Protein 8e-52 44