Gene Information

Name : Hbor_12180 (Hbor_12180)
Accession : YP_004036252.1
Strain : Halogeometricum borinquense DSM 11551
Genome accession: NC_014729
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1129285 - 1130448 bp
Length : 1164 bp
Strand : +
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence :
ATGGACGACGACAGTACTCATCGAATCGAGACGCGCGCGATTCACGCCGGACAAGACCCTGACGAGGAGACGGGTGCCCT
GATGACGCCTATCTACGCCAACTCGACGTACGTGCAAGATGGACCGGGCGACCACCGCGGCTACGAGTACTCGCGGACGG
GGAACCCGACGCGGTCGGACCTCGAAGACAACCTCGCCGCCCTCGAAGGCGGGGAGTTCGGTCGCGCGTTCTCCTCGGGA
ATGGGGGGAATTAACACAGTTCTCAATCTGCTTGAAGCGGGCGACCACGTCGTAACCGGTGACGACGTGTACGGCGGTAC
ACACCGTATCTTCACGCAGGTGTACGACAAGTACGACCTCTCTTTCGACTTCGTAGACACCACCGACCACGATGCCGTGG
CCGATGCGATGCGCGAAGAGACGGCGCTGTTGTGGGCTGAGACGCCGACAAATCCGCTGATGCGTGTCAACGACATCTCG
GCACTCGCGGACCTCGCACACGAGTACGACGCGCTCTGCGCCGTTGACAACACGTTCGCCACGCCGTACCTCCAGCGACC
GCTCGAACACGGTGCGGATATCGTCTCGCATTCGCTGACGAAGTACCTCGGTGGCCACTCTGACGTTGTCGCGGGCGCGC
TCATCACCGACGACGAGGAACTGGACGAAGAGATCGGATTCTACCAGAACTCCGTCGGCGCGACGCCGTCGCCGTTCGAC
TGTTTCCTCGTCCTCCGCGGAACGAAAACGCTTGGCGTCCGGATGGACCGCCACTGCGAGAACGCAAGCGAACTCGCTCG
CTGGCTGGATGACCACGACGCCGTCTCCGACGTGTACTACCCCGGTCTGGAGTCGCACCCGCAACACGAACTCGCAGCCG
AACAGATGGACGACTTCGGTGGAATGCTCTCGTTCGAGGTTGACGGGACGCTTGAACAGGCCTCCACCGTCGTCGAGGAG
ACGGACGTGTTCACGCTTGCAGAGAGTCTCGGCGGCGTCGAGAGCCTCATCGAACAGCCCGCAGCGATGACGCACGCAGC
CATCCCACGCGAGGAACGACTCGAAGCGGGCCTCACCGACGGCCTCGTCCGCGTCTCAGTTGGAATCGAACACGTGGACG
ATATGAAGGCGGATCTCGACGCCGCGTTCGACGCCGCATTCTAG

Protein sequence :
MDDDSTHRIETRAIHAGQDPDEETGALMTPIYANSTYVQDGPGDHRGYEYSRTGNPTRSDLEDNLAALEGGEFGRAFSSG
MGGINTVLNLLEAGDHVVTGDDVYGGTHRIFTQVYDKYDLSFDFVDTTDHDAVADAMREETALLWAETPTNPLMRVNDIS
ALADLAHEYDALCAVDNTFATPYLQRPLEHGADIVSHSLTKYLGGHSDVVAGALITDDEELDEEIGFYQNSVGATPSPFD
CFLVLRGTKTLGVRMDRHCENASELARWLDDHDAVSDVYYPGLESHPQHELAAEQMDDFGGMLSFEVDGTLEQASTVVEE
TDVFTLAESLGGVESLIEQPAAMTHAAIPREERLEAGLTDGLVRVSVGIEHVDDMKADLDAAFDAAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-76 52
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-77 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-57 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hbor_12180 YP_004036252.1 cystathionine gamma-lyase BAC0207 Protein 8e-59 43