Gene Information

Name : LA2_03305 (LA2_03305)
Accession : YP_004031434.1
Strain : Lactobacillus amylovorus GRL 1112
Genome accession: NC_014724
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpE
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 663845 - 665893 bp
Length : 2049 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATAACAATAATAACGAATTTTTTGGCGACTTTGATGATTTATTCAACGCATTAAACGGAAATAACAACAATGCCGC
AAACAACAATAATATGGGAAACAACGACCCAAGAATGCAAATGGGTGGTGGCAACGGAAACGGTGGTCAAGGCGGCAGAA
GCTTGCTTGATCAATATGGTACAGATTTAACCGCCCTTGCTAAGAAAGGCAAAATCGACCCAGTAATCGGCCGTGATAAA
GAAATCGCCCGTGTCATTGAAATTTTAAACAGAAGAACTAAAAACAACCCAGTTTTAATTGGTGAAGCTGGTGTTGGTAA
GACTGCTGTAGTTGAAGGACTTGCTCAAGAAATCGTTGACGGTTCTGTTCCAGCTAAACTGCAAAAAAAGCGTATCATTT
CCTTAAATGTAGTATCACTTGTTCAAGGTACTGGTATCCGTGGTCAATTCGAACAAAGAATGGAACAATTGATCAAGGAA
TTACAACAAAATGACGATATCATCCTATTTATTGATGAGATTCACGAAATTGTTGGTGCCGGAAATGCTGAAGGCGGTAT
GGACGCCGGCAACATTATTAAGCCTGCCCTAGCTCGTGGCGAACTGCAATTAGTAGGTGCTACTACTATTAAGGAATACC
GCGATATTGAAAAGGATTCAGCTTTAGCAAGAAGATTCCAACCTGTTGAAGTTAAGGAACCTTCAATTGATGAAACTACC
CGTATTTTAAGGGGTATTCAAAAGCGTTACGAAGATTACCACCACGTTCACTACACAGACGATGCTATTGAATCTGCTGC
TAAGCTTTCTGCTCGCTACATTCAAGATAGATTCTTGCCTGACAAGGCCATTGACTTACTTGATGAAGCTGGTTCAAGAA
TGAACTTAACTATTCCTTATATTGATAAGGATAAGATGCAAGAAAGAATCAATGCAGCTGAACAATTAAAGGAAGAAGCC
TTGAAGAATGAAGACTACGAAAAGGCTGCTTACTACCGTGATCAAATTGATAAATACAAAAAGGTAAAGGATCAAAAAGT
TGACCCTGACAAATCCCCAGTTATTACCAGCAAGATCATGAACAAGATTGTTGAAGAAAAGACTGGCATCCCTGTCGGCG
ATATTCAAAAGCAAGAAGAAAATCAATTGCAAAATTTGGCTAGTGATTTGAAAGCTCACGTTATCGGTCAAGACAAGGCT
GTTGACAAAGTTGCTCGTGCTATTCGTCGTAACAGAATCGGTTTCAACAAGTCTGGTCGTCCAATTGGTTCCTTCTTATT
CGTAGGACCTACTGGTGTTGGTAAGACTGAACTTGCTAAACAACTTGCTAAGCAAATGTTTGGTTCAGAAGATGCCATGA
TTCGTTTCGATATGTCTGAATACATGGAACAATATTCTGTATCTAAGTTGATTGGTTCAGCTCCTGGTTACGTTGGCTAC
GAAGAAGCTGGTCAATTGACTGAACAAGTTCGTCACAACCCATACAGCTTGATTTTGCTTGACGAAATTGAAAAAGCTCA
CCCAGACGTTTTGAACCTCTTCTTGCAAATCTTAGATGATGGTCGTTTGACTGATTCACAAGGTAGAACTGTTTCATTCA
AAGATACAATCATCATCATGACTTCTAACGCAGGTCAAGGCATCAAGAATGCTAGCGTTGGTTTCGCTGCTGAAAATGAA
GACGAAAGTAATGAATCAGCTAGAAACAACATGAGTCAATTCTTCAAGCCTGAATTCCTTAACCGTCTTGATGACGTCAT
TGAATTCAACGAATTGACTAAACCTGACTTACTTAAGATTGTTGACTTGATGCTTGCTAACACCAACAACATGGTTAAGG
ATCAAGGTTTGTACATTGATGTTACCGACGCAGCTAAAGAAAAATTAGTTGACGAAGGCTTCAACCCTGCTTTAGGTGCA
CGTCCACTTCGTCGTACCATTCAAGAAGAAATTGAAGATAAGGTTGCTGACTACAAGCTCGACCACACTGACAGCAAGAA
CTTAAAGGCTGATGTCAAAGATGGCGAGATCGTAATTAGCGAAGAATAA

Protein sequence :
MNNNNNEFFGDFDDLFNALNGNNNNAANNNNMGNNDPRMQMGGGNGNGGQGGRSLLDQYGTDLTALAKKGKIDPVIGRDK
EIARVIEILNRRTKNNPVLIGEAGVGKTAVVEGLAQEIVDGSVPAKLQKKRIISLNVVSLVQGTGIRGQFEQRMEQLIKE
LQQNDDIILFIDEIHEIVGAGNAEGGMDAGNIIKPALARGELQLVGATTIKEYRDIEKDSALARRFQPVEVKEPSIDETT
RILRGIQKRYEDYHHVHYTDDAIESAAKLSARYIQDRFLPDKAIDLLDEAGSRMNLTIPYIDKDKMQERINAAEQLKEEA
LKNEDYEKAAYYRDQIDKYKKVKDQKVDPDKSPVITSKIMNKIVEEKTGIPVGDIQKQEENQLQNLASDLKAHVIGQDKA
VDKVARAIRRNRIGFNKSGRPIGSFLFVGPTGVGKTELAKQLAKQMFGSEDAMIRFDMSEYMEQYSVSKLIGSAPGYVGY
EEAGQLTEQVRHNPYSLILLDEIEKAHPDVLNLFLQILDDGRLTDSQGRTVSFKDTIIIMTSNAGQGIKNASVGFAAENE
DESNESARNNMSQFFKPEFLNRLDDVIEFNELTKPDLLKIVDLMLANTNNMVKDQGLYIDVTDAAKEKLVDEGFNPALGA
RPLRRTIQEEIEDKVADYKLDHTDSKNLKADVKDGEIVISEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-146 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LA2_03305 YP_004031434.1 ATP-dependent Clp protease ATP-binding subunit ClpE VFG0080 Protein 0.0 62
LA2_03305 YP_004031434.1 ATP-dependent Clp protease ATP-binding subunit ClpE VFG0079 Protein 8e-152 51