Gene Information

Name : Calkr_1247 (Calkr_1247)
Accession : YP_004026368.1
Strain : Caldicellulosiruptor kristjanssonii 177R1B
Genome accession: NC_014721
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1302194 - 1303945 bp
Length : 1752 bp
Strand : +
Note : KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
TTGAGAAAAACAAAAATAATTTGTACATTGGGTCCAGCGACCGACTCAGAGGAGATAATAAGAAAGCTTGTTGAAAATGG
AATGGATGTTGTGAGATTAAATTTTTCTCATGGTACACATGAAGAGCATAAGAAAAAGATTGACATGGTAAAAAAGATAA
GAGAAGAACTTGACAAGCCTATTCCCATTTTGCTTGATACTAAAGGGCCAGAGATAAGAATAGGTTTTTTTAAGGACGGC
AAAGTAGAACTAAAAGAGGGTCAGAAGTTTGTACTGACTGTGGAAGAAATCTTAGGAAATGAAGAGATTGTGAGTATAAC
TTATAAAGAACTTGTTGAGGATGTAAAACCAGGTGATAAAATCCTGATAGATGATGGACTTATTGAGCTTATTGTTGAGG
ACAAGACAGAAAAGAACATAATCTGCAAGGTAAAAAATGGAGGAGTTTTGACTAACCAAAAAGGGGTAAATGTACCGGGC
ATACCCATAAGACTTCCTGCACTTACCCAGAAGGATAAAGAGGATATTCTGTTTGGGATAGAAAACGATGTAGATTTTAT
TGCAGCCTCATTTATAAGAAAGGCAAGTGACGTTGTTGAAATCAGAGAGTTTCTGAACAAAAATGGTGGAAAAGACATTT
TAATAATTGCTAAGATAGAAACTCAAGAAGGTGTTGCCAACTGCGACGAAATAATAAGGGTTGCAGATGGAATTATGGTT
GCAAGAGGAGATTTAGGGGTAGAACTTCCTTTTGAGGAAGTCCCCCTTGTTCAAAAAATGCTCATTGAAAAATGCTACAA
AGCAGGGAAGCCTGTCATAACAGCAACACAGATGCTTGAATCTATGATACGAAATCCAAGACCTACCAGGGCAGAGGTTA
GCGATATTGCCAATGCCATATTTGATGGCACTTCTGCAATAATGCTCTCTGGCGAGACAGCAATGGGCAAATACCCCGTT
GAAAGTGTTGCTACAATGGCAAAGATTGCCGAGAGAGTGGAAAATCAGATTGATTATATCAAGAGATTTCAGTCTCAGGT
ATTTGATATGCCTGTTAACGTTACAAATGCTATTTCGCACGCAACTTGTACAACCGCACATGACCTTGGCGCAAAGGCTA
TTATAACTGTGACAAAGTCAGGTAACACTGCAAGAATGGTGTCAAAATTCAGACCTGCTTGTCCGATTATTGCAACCACA
CCTTGTGAGAAGGTAAGAAGACAGTTGAATCTGTCATGGGGTGTGTATCCATTTTTGGCAGAGTACAAGAGTTCAACCGA
TGATATATTTGACCATGCTGTTGAGATAGCTGTGAAATCCAAGATTGTAAAAAATGGAGATTTAGTTGTTATCACTGCCG
GAGTTCCTGTTGGTGTAAGTGGAACAACAAATATACTTAAAGTTCATGTTGTAGGACATGTTCTGGTTGAAGGGCGTGGC
TGGGGAAGTGGAAAGGTGACAAGCAGGGTCTGTGTTGTAAAAACCATTAATGATCTTAAACAGAATTTTGAAGATGGAGA
TATTATTGTTACAAATCAAACAAATAACGAGTTTATACCATATATGAAAAGAGCATCTGGTATTATCACAGAAGAAGGTG
GACAGAACTCTCATGCAGTAATTGTAGGTGCTGCACTTGATATCCCTGTAATCACAGATGCTAAAAATGCATTAGAGATA
TTAAAAACAGGGATTGTGGTTACAATTGATACTCAAAAAGGCATTGTATTTAGTGGAGAGCAGAAGGTATAA

Protein sequence :
MRKTKIICTLGPATDSEEIIRKLVENGMDVVRLNFSHGTHEEHKKKIDMVKKIREELDKPIPILLDTKGPEIRIGFFKDG
KVELKEGQKFVLTVEEILGNEEIVSITYKELVEDVKPGDKILIDDGLIELIVEDKTEKNIICKVKNGGVLTNQKGVNVPG
IPIRLPALTQKDKEDILFGIENDVDFIAASFIRKASDVVEIREFLNKNGGKDILIIAKIETQEGVANCDEIIRVADGIMV
ARGDLGVELPFEEVPLVQKMLIEKCYKAGKPVITATQMLESMIRNPRPTRAEVSDIANAIFDGTSAIMLSGETAMGKYPV
ESVATMAKIAERVENQIDYIKRFQSQVFDMPVNVTNAISHATCTTAHDLGAKAIITVTKSGNTARMVSKFRPACPIIATT
PCEKVRRQLNLSWGVYPFLAEYKSSTDDIFDHAVEIAVKSKIVKNGDLVVITAGVPVGVSGTTNILKVHVVGHVLVEGRG
WGSGKVTSRVCVVKTINDLKQNFEDGDIIVTNQTNNEFIPYMKRASGIITEEGGQNSHAVIVGAALDIPVITDAKNALEI
LKTGIVVTIDTQKGIVFSGEQKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-105 51
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-105 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Calkr_1247 YP_004026368.1 pyruvate kinase VFG0479 Protein 2e-106 51