Gene Information

Name : Calkro_1435 (Calkro_1435)
Accession : YP_004024110.1
Strain : Caldicellulosiruptor kronotskyensis 2002
Genome accession: NC_014720
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1606250 - 1608007 bp
Length : 1758 bp
Strand : -
Note : KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
TTGAGAAAAACAAAAATAATTTGTACATTAGGTCCAGCGACCGACTCAGAGGAGATAATAAGGAAACTTGTTGAAAATGG
GATGGATGTTGTGAGGTTAAATTTTTCTCATGGTACTCATGAAGAGCATAAGAAAAAGATTGACATGGTAAAAACAATAA
GAGAAGAACTTGACAAGCCTATTCCCATTTTGCTTGACACCAAGGGTCCAGAGATAAGAATAGGTTTTTTTAAAGATGGC
AAAGTAGAACTGAAAGAAGGTCAGAAATTTGTTCTGACTGTGGAAGAAATCTTAGGAAATGAAGAGATTGTTAGTATAAC
TTATAAAGAACTTGTTGAAGATATAAAACCAGGTGATAAAATTCTGATAGATGATGGACTTATTGAGCTTATTGTTGAGG
ACAAGACAGAAAAGAACATAATCTGCAAGGTAAAAAATGGAGGAGTTTTAACCAACCAGAAAGGGGTAAACGTACCGGGT
ATACCCATTAGGCTTCCTGCACTTACCCAGAAGGATAAAGAGGATATTCTGTTTGGGATAGAAAATGATGTAGATTTTAT
TGCAGCCTCATTTATAAGAAAGGCAAGTGACGTTGTTGAAATTAGAGAGTTTCTGAACAAAAATGGTGGAAAGGACATTT
TAATAATTGCCAAGATAGAAACTCAAGAAGGTGTTGCCAACTGCGACGAAATAATAAGAGTTGCAGATGGAATTATGGTT
GCAAGAGGAGATTTAGGGGTAGAACTTCCTTTTGAGGAAGTTCCCCTTGTTCAAAAGATGCTGATTGAGAAGTGTTACAA
AGCAGGAAAGCCTGTCATAACAGCAACCCAGATGCTTGAATCTATGATACGAAATCCAAGACCTACCAGGGCAGAGGTTA
GCGATATTGCCAATGCCATATTTGATGGAACTTCTGCAATAATGCTTTCTGGCGAGACGGCAATGGGCAAATATCCTGTT
GAAAGTGTTGCTACAATGGCAAAGATTGCCGAAAGAGTGGAAAATCAGATTGATTATATCAAGAGATTTCAATCTCAGGT
ATTTGATATGCCAGTTAATGTGACAAATGCTATTTCGCACGCAACTTGTACAACTGCACATGACCTTGGTGCAAAAGCTA
TTATAACTGTAACAAAGTCAGGTAACACTGCAAGAATGGTTTCAAAATTCAGACCTGCTTGTCCGATTATTGCAACCACA
CCTTGTGAGAAGGTTAGGAGACAGCTGAATCTGTCATGGGGTGTGTATCCATTTTTGGCAGAATACAAAAGTTCAACAGA
TGATATATTTGACCATGCTGTTGAGATAGCTGTAAAATCCAAGATTGTAAAAAACGGAGATTTAGTCGTCATTACTGCTG
GAGTTCCTGTTGGCGTGAGTGGAACAACAAATATACTTAAAGTTCATGTCGTTGGACATGTTTTGGTTGAAGGGCGAGGT
TGGGGAAGCGGAAAGGTAACAAGCAGGGTATGCGTTGTTAAAAACATTAATGAACTTAAGCAGAATTTTGAAGATGGAGA
TATAATAGTTACAAGCCAGACAAATAATGAGTTTATACCTTACATGAAAAGGGCTTCGGGAATTATCACAGAAGAGGGTG
GACAGAACTCTCATGCAGTAATTGTAGGTGCTGCACTTGATATCCCTGTAATAACAGATGCTAAAAATGCATTGGAGATA
TTAAAAACAGGGATTGTAGTTACAATTGATACTCAAAAAGGAATAGTATTTAGTGGAGAGCAGAAGATAGAAGAATAA

Protein sequence :
MRKTKIICTLGPATDSEEIIRKLVENGMDVVRLNFSHGTHEEHKKKIDMVKTIREELDKPIPILLDTKGPEIRIGFFKDG
KVELKEGQKFVLTVEEILGNEEIVSITYKELVEDIKPGDKILIDDGLIELIVEDKTEKNIICKVKNGGVLTNQKGVNVPG
IPIRLPALTQKDKEDILFGIENDVDFIAASFIRKASDVVEIREFLNKNGGKDILIIAKIETQEGVANCDEIIRVADGIMV
ARGDLGVELPFEEVPLVQKMLIEKCYKAGKPVITATQMLESMIRNPRPTRAEVSDIANAIFDGTSAIMLSGETAMGKYPV
ESVATMAKIAERVENQIDYIKRFQSQVFDMPVNVTNAISHATCTTAHDLGAKAIITVTKSGNTARMVSKFRPACPIIATT
PCEKVRRQLNLSWGVYPFLAEYKSSTDDIFDHAVEIAVKSKIVKNGDLVVITAGVPVGVSGTTNILKVHVVGHVLVEGRG
WGSGKVTSRVCVVKNINELKQNFEDGDIIVTSQTNNEFIPYMKRASGIITEEGGQNSHAVIVGAALDIPVITDAKNALEI
LKTGIVVTIDTQKGIVFSGEQKIEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-106 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-105 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Calkro_1435 YP_004024110.1 pyruvate kinase VFG0479 Protein 2e-106 51