Gene Information

Name : ureC (REQ_45390)
Accession : YP_004009174.1
Strain : Rhodococcus equi 103S
Genome accession: NC_014659
Putative virulence/resistance : Virulence
Product : urease alpha subunit urec
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 4832787 - 4835006 bp
Length : 2220 bp
Strand : -
Note : -

DNA sequence :
ATGACGGAGGGAGCGAAGTACCTGTACGCCGACGAACCGGTGCCCCTCAATGTCGGGCGCCGGCGAGTTGTGGTCACCGT
GTCGAACATCGGCGACCGCGCGGTGCAGGTGGGCTCGCACTACCACTTCTTCGAGGTCAACCGCGCACTTCGGTTCGACC
GGGCGGCGGCGTACGGGATGCACCTGGACATCGCGTCGGGTACGGCGGTCCGGTTCGAACCGGGAGACACCCGCACCGTC
ACGCTGTGCGAGTTCGGCGGCACCCGTGAGCTCGCTGGGTTCGCCGGGCTGGTCCACGACGGTGGTGACCACGTAGCGCC
GCTCGACGACCCGGACATCCGTTCCGGAGCGTTCCGGCGTGCGGTCGAGCGTGGATTCCTCTCCGCCGCCGACGATTCGG
CCAGCGGATCTGCGGGCGTGACGCCCCGGTCCACGGCCGCAAACTCTGACGGCGACTGCGCGGCGGACCGCCGCGAGCCC
GAGCCGGCCGTTCTGCCGCGACGCACGTATGTCGACCTGTTCGGCCCGTCCGTCGGCGACCGGTTCACGCTCGCAGACAC
GAACCTCGTGGTCGAGGTCGAACGCGACTGCAACGCCGGTGCCTTCGGTGACGAGGCCGTGTACGGCGGTGGTAAAGCCG
TCCGCGACGGCATGGCGCAGGACCCCGCCGCGACCGCCGCGTCCGGGGCTCTCGACCTGGTGATCACCAACGTGGTGGTG
CTCGACGGGGTGCTCGGGGTCGTCAAGGGCGACCTCGGTGTGCGCGCCGGGCGCATCGTCGGTATCGGCAAGGCAGGCAA
CCCGCGTACGCAGGACGGGGTGAGCCCGGGACTGGTGATCGGTCCCGGCACCGAGGTGATCTCGGGCGAGCACCTGGTGG
CGACCGCCGGCGCCGTCGACACCCACGTCCACTTCCTGGCGCCACAGCAGGTGGAGGAGGCGCTCACCAACGGCGTCACC
ACGATGATCGGCGGTGGCACCGGTCCTGCCGACGGCAGCAAGGGCACCACCTGCACACCGGGCCCGTGGCACATCGGCCG
GATGTTGCAGGCCGTCGAGGAGCTGCCGGTGAACGTCGGATTGCTGGGGAAGGCGACGTCGTTGCCGGAGGCGATGGCCG
AGCAGGTCGCAGCAGGACTGTGCGGGATCAAGATCCACGAGGACTGGGGCGCCACGCCCGCGACGATCGATGCCGCGCTG
CGGATCGCCGACGACATGGACGTGCAGGTGGCGATCCACGCCGACACCCTCAACGAGTCGGGATTCTACGAGGACACGCT
CGCTGCGATCGACGGCCGGACCATCCACACCTTCCACACCGAGGGCGCGGGCGGCGGCCACGCCCCGGACATCCTGCGCA
TCGCCGGTGAGCCGAACGTGCTTCCGGCGTCGACCAATCCGACACTGCCGTACACGGTGAACTCGGTCGACGAACTGTTG
GACATGGTGATGGTGTGCCACCACCTGCGGCACGACATCCCCGAGGACGTCTCGTTCGCGGATTCGCGGGTGCGGGCGGA
GACGATCGCAGCGGAGACGGTGCTCCACGACGACGGTGTCATCTCGATCTTCTCGTCCGATTCGCAGGCGATGGGCCGGG
TGGGCGAGACGTGGACGCGCGCGATCCAGACCGCCCATCACTGCAAGGATCAGCGGGGTTCGCTGCCCGAGGACACCGCG
CCGGACGGTTCGTCGCGCAACGACAACAACCGGATCCTGCGGTACGTCGCGAAGACCACGATCAATCCGGCGCTCGCGGC
GGGTGTGGCCGACCACGTCGGTTCACTCGAGCCCGGCAAGCTGGCCGACATCGTGCTGTGGCCGGTCCATTCGTTCGGCG
CCAAGCCGAGTCTCGTGCTCAAGGGCGGCCTGATCTGCTGGTCGGTCATGGGCGACCCCAACGGCTCGATCTCGACACCG
CAGCCGGTGCGGTACCGCCCGATGTACGGTGCGCTGGGTGCGGCGATGCGCGCGACCCGGCTGACGTTCGTATCGCAGGC
GGCGCTCGACGCCGGTGTGCCCGAGAGGTTGGGTCTGCAGAGCCCGGTGGTCGCGGTGCGCGGCTGCCGTTCGGTCGGCA
AGAAGGACATGGTGCGCAACACCGGGACGCCGCAGATCACCGTCGATCCGGACACCTACCACGTCCGCGCAGACGGTGAG
ACCGTCACGATCGCTCCGGCGCAACGCCTTCCGCTCACCCAACTGTTCTACATCGTGTGA

Protein sequence :
MTEGAKYLYADEPVPLNVGRRRVVVTVSNIGDRAVQVGSHYHFFEVNRALRFDRAAAYGMHLDIASGTAVRFEPGDTRTV
TLCEFGGTRELAGFAGLVHDGGDHVAPLDDPDIRSGAFRRAVERGFLSAADDSASGSAGVTPRSTAANSDGDCAADRREP
EPAVLPRRTYVDLFGPSVGDRFTLADTNLVVEVERDCNAGAFGDEAVYGGGKAVRDGMAQDPAATAASGALDLVITNVVV
LDGVLGVVKGDLGVRAGRIVGIGKAGNPRTQDGVSPGLVIGPGTEVISGEHLVATAGAVDTHVHFLAPQQVEEALTNGVT
TMIGGGTGPADGSKGTTCTPGPWHIGRMLQAVEELPVNVGLLGKATSLPEAMAEQVAAGLCGIKIHEDWGATPATIDAAL
RIADDMDVQVAIHADTLNESGFYEDTLAAIDGRTIHTFHTEGAGGGHAPDILRIAGEPNVLPASTNPTLPYTVNSVDELL
DMVMVCHHLRHDIPEDVSFADSRVRAETIAAETVLHDDGVISIFSSDSQAMGRVGETWTRAIQTAHHCKDQRGSLPEDTA
PDGSSRNDNNRILRYVAKTTINPALAAGVADHVGSLEPGKLADIVLWPVHSFGAKPSLVLKGGLICWSVMGDPNGSISTP
QPVRYRPMYGALGAAMRATRLTFVSQAALDAGVPERLGLQSPVVAVRGCRSVGKKDMVRNTGTPQITVDPDTYHVRADGE
TVTIAPAQRLPLTQLFYIV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-149 59
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-149 59
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-136 56
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-136 56
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-136 56
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-136 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004009174.1 urease alpha subunit urec VFG0270 Protein 1e-138 54