Gene Information

Name : Calow_2047 (Calow_2047)
Accession : YP_004003358.1
Strain : Caldicellulosiruptor owensensis OL
Genome accession: NC_014657
Putative virulence/resistance : Unknown
Product : Site-specific DNA-methyltransferase (adenine-specific)
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 2157715 - 2159259 bp
Length : 1545 bp
Strand : -
Note : KEGG: site-specific DNA-methyltransferase (adenine-specific); PFAM: N-6 DNA methylase

DNA sequence :
ATGGGTCAGAATAACGATGGAGTGTTAAACTTTGCTTCAACCCTTTGGGCAGCAGCCGATAGATTGCGAAATAATATGGA
ACCGTCGGAATATAAACATATTGTCCTTGGACTTATATTTTTAAAATATATTTCCGATGCATTTAAATTTCGACAAGAGG
AGTTGGAGTATTTAATAAAAGATCCTAAAAACGAAGAATATTATTGCGGCTCTGAAGAAGAAGCGCAACTTATTTTGGAA
GACAAAGATGAATACATGGCTGCTAATGTATTCTATGTTCCTCCTGAGGCAAGATATGAGTATATTATGGCAAATGCTCG
GCGAAGCGATATAGGAAAACTTATTGATGACGCTATGGATTTGATTGAGAAAGAAAATCCGAAGCAGCTACGAGGTGTTC
TTCCTAAGGTATACACCAAAGCGCCTTTAGATCCGCACACTCTTGGCGAAATTGTCAATTTGATTGGCAGCATTAATTTT
GGTAAAAATGAGGAACTGGATGTTTTAGGGAGAGTTTATGAGTATTTTCTTTCCGAATTTGCCAGAAAAGAGGGTAAGAG
AGGTGGCGAGTTCTTCACGCCATCTAGCGTTGTCAAACTTCTTGTTGAAATGATTCAGCCTCTTCATGGCAGGGTTTTTG
ACCCATGCTGCGGTTCTGGGGGCATGTTTGTTCAGAGCATACGCTTTGTAGAGGCTCATGCAGGCAAGAAAGGTGATATT
TCGATCTATGGGCAGGAGTCCAATCCGACCACTTACAGGCTGTGTAAAATGAACCTTGCAATTCGGGGTATTGAGGCAGA
TATAAGGTTAGGGAATTCCTTCACAGATGACCAATTTAAGGATTTGAGAGCAGATTATATATTGGCAAATCCGCCGTTCA
ATGACAGTGCCTGGGGAGCAGATAGGTTGGCGAATGATGTGAGGTGGAAATACGGGCTGCCGCCAGATTCCAATGCAAAT
TATGCATGGATCCAGCATTTTATTTATCATCTTGCGCCAAAAGGTGTTGCTGGTTTTGTGCTTGCCAATGGTTCTATGAC
TACAAGCAATAATGCGGAGTATGAGATAAGAAAGAGAATTATAGAAGATAACCTTGTTGACTGTATGGTAGCCCTGCCAC
CACAGCTGTTTTACACAACAGGAATTCCTGCATGTTTGTGGTTCATCCGCAAAGGTAGGGAAACGAAAGAAACTCTTTTT
ATCGATGCCAGAAAAATGGGTGTTATGGTGGACAGGACGCATAGAGAACTTACCGATGAGGAAATTCAAAAGATTGCCGA
GACTTATCACAACTGGAGAAATAAAAGTGGGTATGAAGATCTAAAAGGCTTTTGTGCTTCGGTTCCTATGGAGGTTATCG
CACAAAACGATTATGTCCTTGCACCTGGAAGATATGTAGGTGTAGAGGATACACAAGAAGATGATATACCTTTTGAAGAA
AAAATGGCAGAGCTAACTGAAAAACTATATCAGCAGATGAAAGAAGCAAGAAGGCTTGACGAAATTATAAAGGCGAATCT
GGAGGAATTGGGATATGGGGAGTGA

Protein sequence :
MGQNNDGVLNFASTLWAAADRLRNNMEPSEYKHIVLGLIFLKYISDAFKFRQEELEYLIKDPKNEEYYCGSEEEAQLILE
DKDEYMAANVFYVPPEARYEYIMANARRSDIGKLIDDAMDLIEKENPKQLRGVLPKVYTKAPLDPHTLGEIVNLIGSINF
GKNEELDVLGRVYEYFLSEFARKEGKRGGEFFTPSSVVKLLVEMIQPLHGRVFDPCCGSGGMFVQSIRFVEAHAGKKGDI
SIYGQESNPTTYRLCKMNLAIRGIEADIRLGNSFTDDQFKDLRADYILANPPFNDSAWGADRLANDVRWKYGLPPDSNAN
YAWIQHFIYHLAPKGVAGFVLANGSMTTSNNAEYEIRKRIIEDNLVDCMVALPPQLFYTTGIPACLWFIRKGRETKETLF
IDARKMGVMVDRTHRELTDEEIQKIAETYHNWRNKSGYEDLKGFCASVPMEVIAQNDYVLAPGRYVGVEDTQEDDIPFEE
KMAELTEKLYQQMKEARRLDEIIKANLEELGYGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-141 56
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 3e-140 55
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-140 55
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 3e-114 47