Gene Information

Name : Calow_2045 (Calow_2045)
Accession : YP_004003356.1
Strain : Caldicellulosiruptor owensensis OL
Genome accession: NC_014657
Putative virulence/resistance : Unknown
Product : type i site-specific deoxyribonuclease, hsdr family
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 2153365 - 2156466 bp
Length : 3102 bp
Strand : -
Note : TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; KEGG: type I site-specific deoxyribonuclease, HsdR family; SMART: DEAD-like helicase

DNA sequence :
ATGAATCTCAATCAAAATTTTGAGAGTGTGGTAGAGCAGGCGGCCATCAAATGGTTTAAGGACATAGGCTACGAATATTT
ACACGGCAGTAAGATACCAATTGAAGATAGGGAAGACTACAGAGAAGTTATTTTAAAAAATAGGCTTTATAAGGCCTTAA
TAAGATTGAATCCCGAACTTCCGCTGGAGTGCATTGAGGAAGCGGTACGCCAGCTGAAGAACCTCCAGTATCCAAGAATA
GAGTTGAACAACAGAGAGATACATAAAATATACCGCAATGGTGCGAAAGTTACAAGACGCAACAGTGAGGGTGAAGAGGT
AGGAGAAATAGTAAAGATATTTGACTATGAAAACCCAAAAAACAATGATTTTCTTGTCTGCAATCAAGTGAAAATTAAGG
GCGCAGGTGTAAGAATCCCTGATATTGTTGTTTATATTAACGGCCTGCCAGTAGGGTTATTCGAACTGAAAAATCCATTA
GATGAGGCGGCCACAATAGAAGGGGCATATAGACAGCTTGAGCTGTACAAAAGGGATATTCCCGACATTTTTGCTTACAA
TGAGATCTGCGTTGTATCTGATGGGAATAAAGCAAAAGCAGGAACGCTTACTGCACCCTGGGAGAGGTTTTCTGCATGGA
AATCCATTGACGGTGTCAGTAGCGTAGAGGGGATGCCAGAACTTGAAGTTTTGATAAAAGGCATGTTTGATAAAAGAAGA
GTTCTCGACATAATAAGGAATTTTATTACCTTTTCTACTGTTAAGGATGAAGTAATTAAAATTATGGCTATGTATCACCA
GTATTACGGTGTAAATAAAGCAGTAGAAGAAACAATCAGGGCCACATCTCCTGGCGGTGACAGAAGAATAGGCACATTCT
GGCATACTCAAGGCAGCGGCAAAAGCCTTTCTATGGTGTTTTATACGGGAAAGATAATAGAGCTTAAAGAACTTCAGAAT
CCTACAATTGTAGTCATTACCGACCGCAACGACCTTGACGACCAGCTGTATGAAACTTTTTGCAATGCAAGCGACCTAAT
TCCATATCCAAAGCAGGCAGAAAGCGTAGAAGACTTAAAAGAAAAACTTTCGCAGGTTGCGGCTGGGGGCATCTTTTTTA
CCACAATACAGAAATTTCAGGCGGAAGCAGAAGAGGTTTCAGAGGTTGTTGATCCAAAACTTAAAAAAGCTTTAAAGAAG
GGCAAAACCTATCCCCTTCTTTCTGACCGTAGCAATATCATTGTTATTGTCGATGAAGCTCACAGGTCGCACTATGAATT
TATTGACGGCTTTGCGAAGTATATAAGGCAGGCGCTTCCTAACGCCAGCTTCATTGGCTTTACGGGGACACCTATTGATC
TTGAAGACAGGTCTACACTTCAGGTGTTTGGAGACTATATCAGCATCTACGATATGAAGCAGGCGGTAGAAGACAAAGCC
ATTGTGCCCATTTATTATGAGGGAAGGTTGGTAAAGCTTCATTTGATAAACGAAGATATTGACAGAGACTTTGAAGAAGT
GACAGAAGGTGAGGAAGAAGAGGTAAAGAACAAACTCAAGACAAAATGGGCAGCTTTGGAGGCATTAGTGGGGACCAAAG
AAAGGATTGAAACCATAGCAAGGGATATTGTAGAGCACTTCGAAGAAAGGTGCAAGGTTCTTGAGGGCAAAGGCATGATA
GTATGTATGAGCCGAAGGATTTGCGTTGACCTTTACAACGAAATAATTAAGTTAAGACCGCACTGGCACAGTGATGATTT
AGACAAAGGCGTAATTAAAATTGTAATGTCAGGAAATCCTTCGAAAGATCCTAAAGATTTTTTGCCCCACCTATATACGA
AGTTACAAATAAAAGAGATTGAAAAAAGAATGAAAGACCCTAACGATCCTCTTAAACTTGTGATTGTTAGGGATATGTGG
CTTACTGGCTTTGATGTGCCGTGCCTGCATACAATGTATATTGACAAGCCAATGCGAGGGCACAACTTAATGCAGGCTAT
AGCCAGAGTAAACAGGGTCTTTAAGGACAAACCTGCAGGATTGGTTGTAGATTACATCGGTATTGCTGATGACTTAAAAC
TGGCACTGGCAAACTACACAAGAAGCACGGGCAAGGAGGCTGCTACCTTACCCATAGACGAAGCAATAAGGATTATGCAG
GAGAAGTATGATATTGTTTGCTCGTATTTCCACGGCATTGATTTTTCGGGTTGGGAAGAAAAAAGTGCAGAGGACAAATT
AAGTCTTTTAAAGCAGGCTATGGACTTAATAAATAAGGATGAGACCACAAAGAAAAATTTTTTGGATCAGTGCATGGCAT
TGTGCAAGGCTTTTGCCCTTGTAATACCGCGAGAAGAAGCGATGCGTATTCGTTCAGATGTTGCCTTTTTCCAAGCAGTA
AGAAGCAATATTGTCAAATACACGCCGCCTAAAGGGTTATCAATCGAAGAGCTGGACAGTGCCATAAAGCAGATTATTTC
CGAGGGTGTTGCTGCAAGCGACAAACCAATTGACATATTCGATGCGGCGGGGCTTAAAAAACCAGACTTGTCTATTCTGA
GTGAAGAATTTTTAAATAAACTTATTGGGCATGAGAATAAAAACTTGCAGATTGAGGTTTTGCGTAAACTGCTCAATGAT
GAGATTAAGGCTAAGATCAGGAAGAATCATGTAAAGTATGCTTCTTTTAAAGAAATGATAGAAAAAGTTTTGAATAAGTA
TCATAATCGTGCTATTACATCTGCTGAGGTTATAAAACACCTTATTGATTTGGCAAAAGAAATGCAGAATATGGACAAAC
GGGCAAAAGAAATGAACTTAACGGAAGAAGAAATGGCTTTTTACGACATTGTATGTCAGGGTGAAGAGGCTATTTTAAAT
GACGAAGAGGCAAAGGAAATTGCAAGAGAGCTTGTGCGAATTATAAAAAGTAAAACCGAGGGACAGGTAGATTGGACTAT
AAAAGAAAACATTAAGGCATCCATTAGGGCAACGGTAAAAAGATTACTAAGAAGAAAGGGCTTCAAAGATCCACAAAAGC
TTGATAATGTAGTTAAATTGGTCATTGAACAGGCTGTATCTCTCTTTGAAGATGCTGCTTAA

Protein sequence :
MNLNQNFESVVEQAAIKWFKDIGYEYLHGSKIPIEDREDYREVILKNRLYKALIRLNPELPLECIEEAVRQLKNLQYPRI
ELNNREIHKIYRNGAKVTRRNSEGEEVGEIVKIFDYENPKNNDFLVCNQVKIKGAGVRIPDIVVYINGLPVGLFELKNPL
DEAATIEGAYRQLELYKRDIPDIFAYNEICVVSDGNKAKAGTLTAPWERFSAWKSIDGVSSVEGMPELEVLIKGMFDKRR
VLDIIRNFITFSTVKDEVIKIMAMYHQYYGVNKAVEETIRATSPGGDRRIGTFWHTQGSGKSLSMVFYTGKIIELKELQN
PTIVVITDRNDLDDQLYETFCNASDLIPYPKQAESVEDLKEKLSQVAAGGIFFTTIQKFQAEAEEVSEVVDPKLKKALKK
GKTYPLLSDRSNIIVIVDEAHRSHYEFIDGFAKYIRQALPNASFIGFTGTPIDLEDRSTLQVFGDYISIYDMKQAVEDKA
IVPIYYEGRLVKLHLINEDIDRDFEEVTEGEEEEVKNKLKTKWAALEALVGTKERIETIARDIVEHFEERCKVLEGKGMI
VCMSRRICVDLYNEIIKLRPHWHSDDLDKGVIKIVMSGNPSKDPKDFLPHLYTKLQIKEIEKRMKDPNDPLKLVIVRDMW
LTGFDVPCLHTMYIDKPMRGHNLMQAIARVNRVFKDKPAGLVVDYIGIADDLKLALANYTRSTGKEAATLPIDEAIRIMQ
EKYDIVCSYFHGIDFSGWEEKSAEDKLSLLKQAMDLINKDETTKKNFLDQCMALCKAFALVIPREEAMRIRSDVAFFQAV
RSNIVKYTPPKGLSIEELDSAIKQIISEGVAASDKPIDIFDAAGLKKPDLSILSEEFLNKLIGHENKNLQIEVLRKLLND
EIKAKIRKNHVKYASFKEMIEKVLNKYHNRAITSAEVIKHLIDLAKEMQNMDKRAKEMNLTEEEMAFYDIVCQGEEAILN
DEEAKEIARELVRIIKSKTEGQVDWTIKENIKASIRATVKRLLRRKGFKDPQKLDNVVKLVIEQAVSLFEDAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 45
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 45
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 45
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 43