Gene Information

Name : clpA1 (BBMN68_52)
Accession : YP_003999666.1
Strain : Bifidobacterium longum BBMN68
Genome accession: NC_014656
Putative virulence/resistance : Virulence
Product : clpa1
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 52709 - 55318 bp
Length : 2610 bp
Strand : +
Note : ATP-binding subunit of Clp protease

DNA sequence :
ATGTTCGAACGGTTTACCGACCGTGCACGGCGCGTGATCGTGTTGGCGCAGGAAGAGGCGAGGGCCCTTCAGCACAACTA
CATCGGCACCGAACACCTGCTGCTCGGCCTGATCCGCGAAGGTGAGGGTGTAGCCGCCAAGGCACTCGCCTCGAAGGGCG
TGGAGCTGGATGCCACCCGCAAGCAGGTTGAAGAAATGATCGGCAAGGGCAACGCGGCTCCGAACGGGCACATCCCCTTT
ACTCCGCACGCCAAGCAGGTGTTGGAGTTTTCGCTGCGTGAAGCCCTGCAGCTGGGCCACAGCTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATTCGCGAAGGCGAAGGCGTGGGCACCCAGGTGCTCATCAAGATGGACGTCGATCTGGGCGAGT
TGCGTAGCGCGACCATCGATATGATTCGCGGCAACTCCGGCACCGGCACCGGTGACGGCAAGGGCGACTTGGCCAACGCC
GGCGGCGTGACGGACAAGCAGAACAAGTCCGGTTCCGCCATTCTCGATCAGTTCGGCCGCAACCTGACCGCCGAAGCCGC
TGAAGGCAAGCTGGACCCGGTCATCGGCCGTACCAACGAGATTGAGCGCGTTATGGTCGTGCTTTCCCGCCGCACCAAGA
ACAACCCGGTGCTGATCGGCGAGCCCGGCGTGGGCAAGACCGCTGTGGTCGAAGGCTTGGCCCAGAAGATCCAAGCCGGC
GACGTGCCGGAAACCCTGAAGGGCAAGCAGGTCTACTCGCTGGACCTCGGTTCCATGGTGGCCGGCTCCCGCTACCGTGG
TGATTTCGAGGAGCGCCTGAAGAAGGTGCTGAAGGAAATCAAGACCCGTGGTGATATCGTGCTGTTCATCGACGAGATCC
ACACCATCGTGGGCGCCGGCTCGGCTGACGGCGCGCTGGGTGCCTCCGACATGTTGAAGCCGATGCTGGCCCGTGGCGAG
CTCCAGACCATTGGTGCCACCACCACCGACGAGTACCGCAAGTACATCGAGAAGGACGCGGCTCTGGAACGCCGTTTCCA
GCCGATTCAGGTGCACGAGCCGACCATCGCCGAGACCATCGAGATCCTGAAGGGCCTGCGTTCCCGTTACGAGAACCACC
ACCACGTGACCATCACCGATGGCGCGCTGCAGTCCGCCGCAGAGCTGTCTAGCCGGTACATCCAGGACCGTAATCTGCCT
GACAAGGCCATCGACCTGATCGATGAGGCCGGTGCACGCCTGCGCATCAAGCGCCTGACCGCCCCGCCTGAGCTCAAGGA
ACTCGACGAGAAGATCGCCAAGATCGCCGCCGACAAGGACGAGGCCATCAAGGGCCAGGACTTCGAGAAGGCCGCCGAAC
TGCGCGACAAGCAGGAGAAGCTGGAAGCCGATCGCAAGCAGAAGGAAGACTCCTGGCGCGAAGGCGAGTCCGACGTCAAG
ATGGTCGTGGACGAGGACGTGATCGCCGAGGTCATCAGCTCCACCACCGGTATCCCGGTGTTCAAGCTGACTCAGGCCGA
GTCCAAGAAACTGCTCAACATGGAAGCCGAACTGCACAAGCGCATCATCGGCCAGGACGAGGCGGTTTCCGCCCTGTCCC
GCTCTATCCGCCGTACTCGCGTGGGTCTGAAGGACCCGAAGCGCCCGTCCGGCTCGTTCATCTTCGCCGGCCCCACCGGC
GTCGGCAAGACCGAGCTGGCCAAGACGCTCGCCGAATTCCTGTTCGACGATGAGGACGCGCTGATTCGCGTGGATATGTC
CGAGTTCTCCGAGAAGTACGCGGCTTCGCGACTCTTCGGTGCGCCTCCGGGATACGTCGGCTACGAGGAAGGCGGCGAGC
TCACCGAAAAGGTGCGCCGCAAGCCGTTCTCCGTGGTGCTGTTCGACGAGATCGAAAAGGCTCATCCGGACATCTTCAAC
ACGTTGCTGCAGGTGCTCGATGACGGCCACCTGACCGACGGTCAGGGCCGCAAGGTGGACTTTAAGAACACCATCATCAT
CCTGACCACCAACCTCGGTACGCGAGACATCGCCAAGGCCGCCAACACGGGCTTCAACCTAGGTGCCAACAACGAGTCCA
GCTACCAGCGCATGAAGGACCAGGTCAGCTCCGAATTGAAGCAGCAGTTCCGCCCGGAGTTCCTGAACCGTCTGGACGAC
ATCATCGTCTTCAAGCAGCTCACCGAGCCGCAGGTGCGCCAGATCGTGGATCTGGACGTCAAGCAGCTCAACGACCGCCT
GTTCGACCGTCATATGTCGCTCGAACTCACCGACGCCGCCAAGGACCTGCTCGCGCAGAAGGGCTTCGACCCGCTGCTCG
GTGCCCGTCCGCTGCGCCGCGTGATTCAGCGCGACATCGAGGACGCCATCTCCGAGAAGATCCTGATGGGCGATCTCGAA
GACGGTCAGCGCGTGATTGTGGATGCGGAAGGCGAGGGTATCCTCGGCGAATTCACCTTCAAGGGTGAGGAGTTCGAGGA
GCCGGCCGCCGCCGATAGGCCCGCCGAAGACGGTGCCGCCACTGATGGCGAGACTCCAGCCGACGCCACTCCGGCCACTG
AACCGGCCGAATCCGCTCCCGCCGATTCCGGTGACGCTCCGCAGGAGTAG

Protein sequence :
MFERFTDRARRVIVLAQEEARALQHNYIGTEHLLLGLIREGEGVAAKALASKGVELDATRKQVEEMIGKGNAAPNGHIPF
TPHAKQVLEFSLREALQLGHSYIGTEHILLGLIREGEGVGTQVLIKMDVDLGELRSATIDMIRGNSGTGTGDGKGDLANA
GGVTDKQNKSGSAILDQFGRNLTAEAAEGKLDPVIGRTNEIERVMVVLSRRTKNNPVLIGEPGVGKTAVVEGLAQKIQAG
DVPETLKGKQVYSLDLGSMVAGSRYRGDFEERLKKVLKEIKTRGDIVLFIDEIHTIVGAGSADGALGASDMLKPMLARGE
LQTIGATTTDEYRKYIEKDAALERRFQPIQVHEPTIAETIEILKGLRSRYENHHHVTITDGALQSAAELSSRYIQDRNLP
DKAIDLIDEAGARLRIKRLTAPPELKELDEKIAKIAADKDEAIKGQDFEKAAELRDKQEKLEADRKQKEDSWREGESDVK
MVVDEDVIAEVISSTTGIPVFKLTQAESKKLLNMEAELHKRIIGQDEAVSALSRSIRRTRVGLKDPKRPSGSFIFAGPTG
VGKTELAKTLAEFLFDDEDALIRVDMSEFSEKYAASRLFGAPPGYVGYEEGGELTEKVRRKPFSVVLFDEIEKAHPDIFN
TLLQVLDDGHLTDGQGRKVDFKNTIIILTTNLGTRDIAKAANTGFNLGANNESSYQRMKDQVSSELKQQFRPEFLNRLDD
IIVFKQLTEPQVRQIVDLDVKQLNDRLFDRHMSLELTDAAKDLLAQKGFDPLLGARPLRRVIQRDIEDAISEKILMGDLE
DGQRVIVDAEGEGILGEFTFKGEEFEEPAAADRPAEDGAATDGETPADATPATEPAESAPADSGDAPQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA1 YP_003999666.1 clpa1 VFG0079 Protein 0.0 57
clpA1 YP_003999666.1 clpa1 VFG0080 Protein 3e-135 51