Gene Information

Name : Lbys_0845 (Lbys_0845)
Accession : YP_003996946.1
Strain : Leadbetterella byssophila DSM 17132
Genome accession: NC_014655
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 900359 - 901654 bp
Length : 1296 bp
Strand : -
Note : COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: cpi:Cpin_4763 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisa

DNA sequence :
ATGGAGTTTAAGTATCATTTAGCCATTATCGGGCAGGGTTATGTAGGACTACCTCTAGCTATCGAATTTGCTCATCATTT
CCCTGTTTTAGGATTTGATATCCAAGAAGAAAGAGTAAGAGAATTAAACGCTGGACAGGATAGAACCCTAGAGGCTGATT
TGCCAAAATTGAAGCATGTTCTGCAATTGGGCAATAAAGAACCATGGGCAGAAGGCTATAGGGCCTCATCGTCACTCGAA
GATCTGAAGAAGGCTAATGTCTTTATTGTTACTGTTCCTACTCCTATTGATACCTTTAATGCACCAGATCTTAAACCATT
ACTTTCAGCCACAGAAATGCTGGGAAAAGTCCTTAAAAAGGGAGATATGGTTATTTATGAAAGTACAGTATTTCCGGGAT
GTACGGAAGAAGAATGCGTACCTGTGTTAGAGAGAGAGTCGGGACTAAGGTATAATGTAGACTTTTATGTAGGTTATTCT
CCGGAAAGGATAGTACCTGGCGACAAGGTTCACACTTTGACAAAGATCAAGAAAGTAACCTCAGGTTCAACCCCGGAGAT
TGCCAAAAAAGTAGATGATCTGTATAAAAAGATTATAGAAGCAGGCACCCATTTGGCTCCATCTATCAAAGTAGCAGAAG
CTTCAAAGGCCATTGAAAATGCACAAAGAGATATCAATATTTCTTTTGTCAATGAATTGGCATTGATTTTTGACCGGATA
GGGATAGATACCCATGATGTGCTTGAAGCTGCGGGAACGAAATTCAACTTCCTCAAGTACCAACCGGGCCTGGTAGGCGG
GCACTGTATCTCCGTGGATCCTTACTATCTGGCGCATAAAGCTACCCAATTGGGCTATCATCCAGCAGTAATTCTATCCG
GACGCCGAGTAAATGATTCTGTGGCAGAGTTTGTAGCCTCAAAGGTGGTTAAATTAATGATAGAAAAGGATCTTCAAGTG
AAAGGATCTAAAGCGCTGGTCTTAGGTTTTACCTTTAAGGAAAACTGTCCGGATGTGAGAAACACCAAGGTGATAGATGT
TTATCATGAATTGAGAGAATATGGTCTAGAGGTAGATGTATATGATCCATGGGCAGATCAGGAAGAAGTAAAGCACGAAT
ATGGACTTCAGCTTATAGAATCATTACCAGATGCCGCTACCTATAATTCCATTATATTGGCAGTTGCTCATAGGGAATTC
CTGGAAATTGATTTGAATACGCTTAAAAAAGAAAAAGCCGTGATATTTGATATCAAGGCTTGTCTTCCACGAGAAATAGT
GGACGGTAGATTATAA

Protein sequence :
MEFKYHLAIIGQGYVGLPLAIEFAHHFPVLGFDIQEERVRELNAGQDRTLEADLPKLKHVLQLGNKEPWAEGYRASSSLE
DLKKANVFIVTVPTPIDTFNAPDLKPLLSATEMLGKVLKKGDMVIYESTVFPGCTEEECVPVLERESGLRYNVDFYVGYS
PERIVPGDKVHTLTKIKKVTSGSTPEIAKKVDDLYKKIIEAGTHLAPSIKVAEASKAIENAQRDINISFVNELALIFDRI
GIDTHDVLEAAGTKFNFLKYQPGLVGGHCISVDPYYLAHKATQLGYHPAVILSGRRVNDSVAEFVASKVVKLMIEKDLQV
KGSKALVLGFTFKENCPDVRNTKVIDVYHELREYGLEVDVYDPWADQEEVKHEYGLQLIESLPDAATYNSIILAVAHREF
LEIDLNTLKKEKAVIFDIKACLPREIVDGRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-110 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-110 54
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-102 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lbys_0845 YP_003996946.1 nucleotide sugar dehydrogenase VFG0431 Protein 2e-110 54