Gene Information

Name : Lbys_3025 (Lbys_3025)
Accession : YP_003999040.1
Strain : Leadbetterella byssophila DSM 17132
Genome accession: NC_014655
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 3417022 - 3417684 bp
Length : 663 bp
Strand : -
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: zpr:ZPR_0969 two-component system response regulator; PFAM: response regulator receiver; transcriptional

DNA sequence : 
TTGATTGAAGACGATCATCAGGTTTGCGCCATCGTTAAAAAGGGCTTAGAAGAAGAAAATTTCGAGGTGACCATTGCCAC
GGATGGTGATACGGGGCTTTCTATGGCTAGTGAGGAAAACTATGATCTAATTATATTAGACATTATGCTTCCAAAGAAAT
CCGGTCTAGAAGTGTGCACCCGGATTAGACATACCAGTAATATTCCCATTTTACTTCTCACTGCATTAGGTACTGCAGAG
AATGTGGCAGAAGGTTTAAACAGAGGTGCAGATGACTACCTTGTAAAACCATTTAAGTTCATTGAACTTATAGCCAGAAT
TAATAGCCTATTAAGAAGAGCAGGTAGAGAAGAAGAGAAATCTGAGGTATATAAATTCTCCGGAGTAGTACTTAACAATA
CTTCAAAAACCGTTACGGTGAATGATCAAGAGGTAGCTTTAACCTCAACAGAATTTAAGTTGCTCCTGCTTTTAATGAAG
ATGCCTAATAAAGTATACTCTCGCCAGGAGATCCTAGAGAGAGTATGGGAAGTTAATTTTGATTTAGGCACTAATGTAGT
GGATGTATATATCAATTATCTAAGGAAGAAGCTGGACAAACACGGCTCTCCTAAGATCATCCACACAGTAGTGGGAATGG
GATATGTATTAAGGGAAAAGTAG

Protein sequence : 
MIEDDHQVCAIVKKGLEEENFEVTIATDGDTGLSMASEENYDLIILDIMLPKKSGLEVCTRIRHTSNIPILLLTALGTAE
NVAEGLNRGADDYLVKPFKFIELIARINSLLRRAGREEEKSEVYKFSGVVLNNTSKTVTVNDQEVALTSTEFKLLLLLMK
MPNKVYSRQEILERVWEVNFDLGTNVVDVYINYLRKKLDKHGSPKIIHTVVGMGYVLREK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-29 41
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 4e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator BAC0125 Protein 2e-35 47
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator BAC0197 Protein 2e-36 45
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_002758.1121390.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_010079.5776364.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_002952.2859858.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_007622.3794948.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_003923.1003417.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_013450.8614146.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_002951.3238224.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator NC_007793.3914065.p0 Protein 1e-38 44
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator AE015929.1.gene1106. Protein 5e-36 43
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator BAC0111 Protein 3e-36 43
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator BAC0347 Protein 3e-29 41
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator U82965.2.orf14.gene. Protein 3e-25 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator VFG1389 Protein 3e-34 42
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator VFG0596 Protein 4e-30 41
Lbys_3025 YP_003999040.1 winged helix family two component transcriptional regulator VFG1390 Protein 4e-42 41