Gene Information

Name : Calhy_0173 (Calhy_0173)
Accession : YP_003991301.1
Strain : Caldicellulosiruptor hydrothermalis 108
Genome accession: NC_014652
Putative virulence/resistance : Resistance
Product : two component transcriptional regulator, winged helix family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 225762 - 226436 bp
Length : 675 bp
Strand : -
Note : KEGG: gyc:GYMC61_1696 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver

DNA sequence : 
ATGCCACGGATACTAATTGTGGACGATGACCCACATATTAGAGAACTTGTTGCACATTTTTTGACCCTTGAAGGCTTTGA
CATATATGAGGCAGCAAATGGAAAAGATGCACTTAACATACTTGATACAGTTAAAGTTGATTTAGTCATATTAGATATTA
TGATGCCAGAAATAGATGGTTGGCAGCTTTGTCATAATATTCGGAAATATTATGGCGACATACCTATTTTGATGTTGACA
GTCAAAGGTGAAACAAATGATAAAGTGAAAGGATTTGAAGTGGGAGCTGACGACTATCTTGTTAAACCATTTGATCCGAT
AGAACTTGTTGCCCGAGTCAAAGCTCTACTTAGACGTTATCAAATATCAACATCACAGACAATTAAGATTGGTGAGTTGT
TTCTAAATAAAAAAACATATGAATGTCGCGTTGGAGAAGAAGAAATTCTTCTGCCACCAAAAGAATTCGAACTACTGTTC
AAGTTAGCAAGCTATCCAGGAAAAACATTTACACGCGACCAATTGATTGAAGAAATCTGGGGCTATGACTATGAGGGAGA
TGAAAGAACTGTGGATGTCCATATTAAAAGATTAAGAGAAAAATTTTCAAAATACTGTATCTTTGTAATTAGAACAATTC
GCGGACTTGGTTATAGATTGGAGGTCATTAAATGA

Protein sequence : 
MPRILIVDDDPHIRELVAHFLTLEGFDIYEAANGKDALNILDTVKVDLVILDIMMPEIDGWQLCHNIRKYYGDIPILMLT
VKGETNDKVKGFEVGADDYLVKPFDPIELVARVKALLRRYQISTSQTIKIGELFLNKKTYECRVGEEEILLPPKEFELLF
KLASYPGKTFTRDQLIEEIWGYDYEGDERTVDVHIKRLREKFSKYCIFVIRTIRGLGYRLEVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 1e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_012469.1.7685629. Protein 5e-41 46
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_012469.1.7686381. Protein 2e-36 45
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family AM180355.1.gene1830. Protein 3e-39 44
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family AE000516.2.gene3505. Protein 9e-35 43
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family HE999704.1.gene2815. Protein 3e-41 42
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family AF130997.1.orf0.gene Protein 8e-36 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family AF310956.2.orf0.gene Protein 5e-35 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_002952.2859905.p0 Protein 6e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_007622.3794472.p0 Protein 6e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_002745.1124361.p0 Protein 4e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_009782.5559369.p0 Protein 4e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_002951.3237708.p0 Protein 4e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_003923.1003749.p0 Protein 4e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_002758.1121668.p0 Protein 4e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_009641.5332272.p0 Protein 4e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_013450.8614421.p0 Protein 4e-39 41
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family NC_007793.3914279.p0 Protein 4e-39 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Calhy_0173 YP_003991301.1 two component transcriptional regulator, winged helix family VFG1389 Protein 1e-30 41