Gene Information

Name : Calhy_1460 (Calhy_1460)
Accession : YP_003992546.1
Strain : Caldicellulosiruptor hydrothermalis 108
Genome accession: NC_014652
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1490116 - 1491873 bp
Length : 1758 bp
Strand : -
Note : KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
TTGAGAAAAACAAAAATAATTTGTACATTGGGTCCAGCGACCGACTCAGAGGAGATAATAAGAAAACTTGTTGAAAATGG
AATGGATGTTGTGAGATTAAATTTTTCTCATGGTACTCATGAAGAGCATAAGAAAAAGATTGACATGGTAAAAAAAATAA
GAGAAGAACTTGACAAGCCTATTCCCATTTTGCTTGATACTAAAGGGCCAGAGATAAGAATAGGTTTTTTTAAGGACGGC
AAAGTAGAACTAAAAGAGGGTCAGAAATTTGTGCTGACTGTGGAAGAAATCTTAGGAAATGAAGAGATTGTGAGTATAAC
TTATAAAGAACTTGTTGAGGATGTAAAACCAGGTGATAAAATTCTGATAGATGATGGACTTATTGAGCTTATTGTTGAGG
ACAAGACAGAAAAGGACATAATCTGCAAGGTAAAAAATGGAGGAGTTTTGACCAACCAGAAAGGGGTAAACGTACCGGGC
ATACCCATAAGACTTCCTGCACTTACCCAGAAGGATAAAGAGGATATTCTGTTTGGGATAGAAAACGATGTAGATTTTAT
TGCAGCCTCATTTATAAGAAAGGCAAGTGACGTTGTTGAAATCAGAGAGTTTCTGAACAAAAATGGTGGAAAGGACATTT
TAATAATTGCCAAAATAGAAACTCAAGAAGGTGTTGCCAACTGCGACGAAATAATAAGGGTTGCAGACGGAATTATGGTT
GCAAGAGGAGATTTAGGGGTAGAACTTCCTTTTGAGGAAGTCCCCCTTGTTCAAAAAATGCTCATTGAAAAATGCTACAA
AGCAGGAAAGCCTGTCATAACAGCAACACAGATGCTTGAATCTATGATACGAAATCCAAGACCTACCAGGGCAGAGGTTA
GCGATATTGCCAATGCCATATTTGATGGCACTTCTGCAATAATGCTCTCTGGCGAGACAGCAATGGGCAAATACCCCGTT
GAAAGTGTTGCTACAATGGCAAAGATTGCCGAGAGAGTGGAAAATCAGATTGATTATATCAAGAGATTTCAGTCTCAGGT
ATTTGATATGCCTGTTAATGTGACAAATGCTATTTCGCACGCAACTTGTACAACCGCACATGACCTTGGCGCAAAGGCTA
TTATAACCGTGACAAAGTCAGGCAACACTGCAAGAATGGTGTCAAAATTCAGACCTGCTTGTCCGATTATTGCAACCACA
CCTTGTGAGAAGGTAAGGAGACAGTTGAATCTGTCATGGGGTGTGTATCCATTTTTGGCAGAGTACAAGAGTTCAACCGA
TGATATATTTGACAATGCTGTTGAGATAGCTGTGAAATCCAAAATTGTAAAAAATGGAGATTTGGTTGTCATTACTGCTG
GAGTTCCTGTTGGCGTGAGTGGAACAACAAATATACTTAAAGTTCATGTTGTAGGACATGTTCTGGTTGAAGGGCGAGGC
TGGGGAAGTGGAAAGGTGACAAGCAGGGTATGCGTTGTGAAAAACATTAATGAGCTTAAGCAGAATTTTGAAGATGGAGA
TATAATAGTTACAAGCCAGACAAATAATGAGTTTATACCTTACATGAAAAGGGCTTTGGGAATTATCACAGAAGAGGGTG
GACAGAACTCTCATGCAGTAATTGTAGGTGCTGCACTTGATATCCCTGTAATCACAGATGCTAAAAATGCATTGGAGATA
TTAAAAACAGGGATTGTGGTTACAATTGATACTCAAAAAGGAATAGTATTTAGTGGAGAGCAGAAGACAGAAGAATAA

Protein sequence :
MRKTKIICTLGPATDSEEIIRKLVENGMDVVRLNFSHGTHEEHKKKIDMVKKIREELDKPIPILLDTKGPEIRIGFFKDG
KVELKEGQKFVLTVEEILGNEEIVSITYKELVEDVKPGDKILIDDGLIELIVEDKTEKDIICKVKNGGVLTNQKGVNVPG
IPIRLPALTQKDKEDILFGIENDVDFIAASFIRKASDVVEIREFLNKNGGKDILIIAKIETQEGVANCDEIIRVADGIMV
ARGDLGVELPFEEVPLVQKMLIEKCYKAGKPVITATQMLESMIRNPRPTRAEVSDIANAIFDGTSAIMLSGETAMGKYPV
ESVATMAKIAERVENQIDYIKRFQSQVFDMPVNVTNAISHATCTTAHDLGAKAIITVTKSGNTARMVSKFRPACPIIATT
PCEKVRRQLNLSWGVYPFLAEYKSSTDDIFDNAVEIAVKSKIVKNGDLVVITAGVPVGVSGTTNILKVHVVGHVLVEGRG
WGSGKVTSRVCVVKNINELKQNFEDGDIIVTSQTNNEFIPYMKRALGIITEEGGQNSHAVIVGAALDIPVITDAKNALEI
LKTGIVVTIDTQKGIVFSGEQKTEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-105 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-105 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-105 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-105 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Calhy_1460 YP_003992546.1 pyruvate kinase VFG0479 Protein 5e-106 51