Gene Information

Name : GY4MC1_2219 (GY4MC1_2219)
Accession : YP_003989564.1
Strain : Geobacillus sp. Y4.1MC1
Genome accession: NC_014650
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 2196835 - 2198547 bp
Length : 1713 bp
Strand : -
Note : KEGG: gyc:GYMC61_2771 urease, subunit alpha; TIGRFAM: urease, subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein

DNA sequence :
ATGAGTTTTCAAATGTCACGGAAACAATATGTGGACATGTTTGGACCGACAACAGGAGATTGTGTTCGTTTAGCGGATAC
CGATTTATGGATTGAGATTGAAAAAGATTTTACCGTTTATGGCGATGAAGTGAAATTTGGCGGCGGAAAAGTCATTCGCG
ATGGAATGGGGCAACATCCGCTTGCCATGCGTGCGGAATCGGTAGATTTAGTACTGACGAACGCGATTATTGTAGACTAT
ACCGGAATTTATAAAGCAGATATCGGGATTAAAGACGGCAAGATCGCTGCCATTGGGAAAGCGGGCAATCCGTTGTTAAT
GGATGGAGTCAATATCATCATTGGAGCGGCGACAGAAGTTATTGCAGCGGAGGGGAAAATTGTCACTGCAGGAGGAATTG
ACGCCCATATTCACTTTATTTGTCCGCAACAAATCGAAACGGCCTTGTCATCGGGGATTACGACGATGATCGGCGGAGGA
ACCGGGCCGGCAACGGGAACCAATGCGACGACGTGCACTCCTGGAGAGTGGAACATCTATCGCATGCTAGAAGCGGCCGA
AGCGTTTCCGATGAATCTTGGATTTTTAGGAAAAGGCAACGCATCGGCGAAAGAGCCGTTAGCGGAGCAAATCCGCGCAG
GAGCCATTGGCCTAAAGCTTCATGAAGATTGGGGGACAACCGCAGCAGCCATTGATGCGAGTTTGCAAGTTGCGGACGAA
TATGATGTGCAAGTGGCGATTCATACCGATACATTGAATGAAGGAGGATTTGTCGAAGATACGTTGCGGGCGATTAACGG
TCGCGTCATTCACACCTATCATACGGAAGGAGCAGGAGGAGGGCATGCGCCTGATATTATTAAAGTAGCGAGTTTTCCAA
ATATACTGCCTTCTTCTACCAATCCAACGCGGCCTTATACGAAAAATACGTTAGATGAGCATTTAGACATGTTGATGGTT
TGTCATCATTTAGACCCGTCTGTTCCCGAAGATATTGCTTTTGCGGATTCTCGCATTCGCAAAGAAACGATTGCGGCGGA
AGATATTCTCCATGATTTAGGTGTTTTTAGCATGATCAGTTCCGATTCGCAGGCGATGGGCCGCGTCGGGGAAGTAATTT
TGCGCACATGGCAAACGGCGGATAAGATGAAAAAGCAATTTGGAAAATTACCAGAAGATAAAGGAAGAAATGGAGATAAT
TTTCGCGTCAAGCGGTACATTGCCAAATATACGATTAATCCGGCGCTTACCCATGGGATTGCGAAGTACGTCGGATCGAT
CGAAGTGGGCAAATTGGCCGATTTAGTTGTTTGGCATCCTGCGTTTTTCGGCGTAAAACCAGAACTTGTTTTGAAAGGGG
GAATGATTGCCTACAGCGTCATGGGAGACCCAAATGCCAGCATTCCAACTCCGCAGCCAGCCATGTATCGACCGATGTTC
GCAAGCTATGGAAAAGCCTTATATAACACTTCGATTACATTTGTATCGAAAGCAGCTTTTGAGCGCGGAATCCCGCAGAA
ATTGAAGTTGCAAAAAATCATTCGACCGGTAGAACGCATTCGCAGCTTGTCGAAAAACGATATGGTGTATAACAATGCGA
TGCCAAAGATTGATGTCGATCCGCAAACGTATGAAGTAAAAGTGGACGGAACCATTATTACGTGTGAACCAGCCGAAGTA
ATCCCGATGGCGCAACGATATTTTTTATTTTGA

Protein sequence :
MSFQMSRKQYVDMFGPTTGDCVRLADTDLWIEIEKDFTVYGDEVKFGGGKVIRDGMGQHPLAMRAESVDLVLTNAIIVDY
TGIYKADIGIKDGKIAAIGKAGNPLLMDGVNIIIGAATEVIAAEGKIVTAGGIDAHIHFICPQQIETALSSGITTMIGGG
TGPATGTNATTCTPGEWNIYRMLEAAEAFPMNLGFLGKGNASAKEPLAEQIRAGAIGLKLHEDWGTTAAAIDASLQVADE
YDVQVAIHTDTLNEGGFVEDTLRAINGRVIHTYHTEGAGGGHAPDIIKVASFPNILPSSTNPTRPYTKNTLDEHLDMLMV
CHHLDPSVPEDIAFADSRIRKETIAAEDILHDLGVFSMISSDSQAMGRVGEVILRTWQTADKMKKQFGKLPEDKGRNGDN
FRVKRYIAKYTINPALTHGIAKYVGSIEVGKLADLVVWHPAFFGVKPELVLKGGMIAYSVMGDPNASIPTPQPAMYRPMF
ASYGKALYNTSITFVSKAAFERGIPQKLKLQKIIRPVERIRSLSKNDMVYNNAMPKIDVDPQTYEVKVDGTIITCEPAEV
IPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-169 69
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-169 69
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-165 66
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-167 66
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-167 66
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-167 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GY4MC1_2219 YP_003989564.1 urease subunit alpha VFG0270 Protein 5e-162 67