Gene Information

Name : GY4MC1_1725 (GY4MC1_1725)
Accession : YP_003989110.1
Strain : Geobacillus sp. Y4.1MC1
Genome accession: NC_014650
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1688193 - 1690313 bp
Length : 2121 bp
Strand : +
Note : KEGG: gwc:GWCH70_1718 heavy metal translocating P-type ATPase; TIGRFAM: cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protei

DNA sequence :
ATGGAAAATAAACAAGTGTACCGTCTTCAAGGACTTTCATGCGCCAATTGCGCAGCAACGTTTGAAAAAAATGTGAAGGC
GATTGCGACGGTGAAAGATGCCAAAGTCAATTTCGGTGCGGCGACACTGACGGTCATCGGCGAAGCGTCGATCGAAGAAC
TTGAAAAAGCGGGAGCGTTTGACAGGATTGCCGTTATTCCGGAAACGGAGCGAAAAGACCAAAAGGCAGAACCGTTTTGG
AAAAAGAAAACAAACGTCATCGCGCTGATATCGGCTTTCTTTCTTCTTGCTGGCTATGTGTCTGCTTATGCGATGGGGGA
ACGGCATATTGCCACCATTTTGTTATTTGCGGCAAGCATCATCATTGGCGGTTATTCTTTGTTAAAAACAGGACTTGCCA
ATCTTGTGCGGCTTCAATTTGATATGAACACTTTAATGACGATCGCTGTCATTGGGGCGGCGTGCATCGGAGAATGGAAA
GAAGGAGCGGTTGTCGTCTTCCTGTTTGCGATCAGTGAAGCGCTCGAGCGCTATTCCATGGATACGGCGCGCCGTTCGCT
TCAGCGGCTCATGGATATCGCTCCGAAAAAAGCGACCGTGCTTCGGGATGGCAAAGAGTATGAAGTGGATGTGGAAGATG
TCGTTGTCGGCGATACGATTCTTGTGAAGCCGGGGCAAAAAATCGCGATGGACGGCGTTGTGCTTCGCGGGGAGTCGTTG
GTTAACGAAGCGGCGATTACCGGCGAATCGATGCCAGTCGCCAAAAACGTCGGCGATGAAGTATATGCGGGAACGATGAA
CGAAGATGGCGCCCTTGAAGTACGGGTGACAAAGCGCGTAGAAGACACAACGATTGCGAAAATCATTCATCTTGTCGAAG
AAGCGCAGGCCGAGCGGGCGCCAACCCAGCAGTTTGTCGACCGCTTTGCCCGCTACTATACACCAACGATTATGCTGATC
GCCTTGTTTGTTGCCACTGTGCCGCCGCTGTGGCTTGGCGGAGAATGGCTGACATGGGTTTACCGCGGCTTAACGGTGCT
TGTTGTCGGCTGTCCGTGCGCTCTTGTCATAAGCACGCCGGTAGCGATCGTAACTGCCATTGGACAAGCGGCGCGGCAAG
GGGTGCTGATTAAAGGCGGGGTGTATTTAGAAGAAATCGGAAAGATATCGGCAATTGCATTTGATAAAACAGGAACGTTA
ACGACAGGGATACCGGAAGTGGCTGATATTTATTCATTTAGCGACTTGGATGAAAAGGAATTGTTAAAAATCGCCGCAGC
CATTGAGAAACAGTCGGAGCATCCGCTTGCTTCCGCCATTTTGCGCAAGGCAGAGGCATTGCAAATATCATCCGACGATT
TGCAAGTAAGCGAGTTTCGCGCTATGGCTGGCAAAGGTGCGGCAGCCCGTGTGAATGGAGTTATGTATTATATTGGGAAA
CCGTCTTTGTTCTCTGAGGCTATACATGAAGACATTCGTGCGCAAATTGCCCGCGAACAAACACAAGGAAAAACAGTCAT
GTTGCTTGGAAATGAAACAAAAGTGCTTGGCATGATTGCCGTTTCCGATCAACTGCGTGAAAATGCCGCTTCTGTGCTAG
AAACATTACGCAACTTAGGAATCTCGCAAACTATCATGTTAACCGGCGATCACGAAACGACCGCGCGGGCCATTGCCTCT
TCCCTTCCGCTTACCGATATTCGCGCTGAATTGCTTCCAGAAGAAAAATGGACGGCGATTCAAACGCTGCAGCGTCAATC
AGGACGCATCGCGATGGTCGGCGATGGTGTCAACGACGCTCCCGCGCTTGCTGCGGCAGATGTTGGCATTGCGATGGGGG
ATATTGGCACCGATGTGGCGTTAGAAACAGCGGACGTTGTCTTAATTGGCGATGATCTTGAAAAGCTTCCGTATGTCATC
CGGTTAGGACGAAAAGCAATGCGCATTATTCAAGAGAACATCGCGGTTGCCTTGTTGTTAAAAGTGTTGGCGCTCGTTCT
CATTGTTCCTGGCTGGCTTACATTGTGGATGGCCATTTTTGCGGATATGGGGGCGACGCTGCTCGTATTGCTCAATTCGC
TGCGGCTGCTCCGCCTTGATGGGATCAGCAAAAAACGATGA

Protein sequence :
MENKQVYRLQGLSCANCAATFEKNVKAIATVKDAKVNFGAATLTVIGEASIEELEKAGAFDRIAVIPETERKDQKAEPFW
KKKTNVIALISAFFLLAGYVSAYAMGERHIATILLFAASIIIGGYSLLKTGLANLVRLQFDMNTLMTIAVIGAACIGEWK
EGAVVVFLFAISEALERYSMDTARRSLQRLMDIAPKKATVLRDGKEYEVDVEDVVVGDTILVKPGQKIAMDGVVLRGESL
VNEAAITGESMPVAKNVGDEVYAGTMNEDGALEVRVTKRVEDTTIAKIIHLVEEAQAERAPTQQFVDRFARYYTPTIMLI
ALFVATVPPLWLGGEWLTWVYRGLTVLVVGCPCALVISTPVAIVTAIGQAARQGVLIKGGVYLEEIGKISAIAFDKTGTL
TTGIPEVADIYSFSDLDEKELLKIAAAIEKQSEHPLASAILRKAEALQISSDDLQVSEFRAMAGKGAAARVNGVMYYIGK
PSLFSEAIHEDIRAQIAREQTQGKTVMLLGNETKVLGMIAVSDQLRENAASVLETLRNLGISQTIMLTGDHETTARAIAS
SLPLTDIRAELLPEEKWTAIQTLQRQSGRIAMVGDGVNDAPALAAADVGIAMGDIGTDVALETADVVLIGDDLEKLPYVI
RLGRKAMRIIQENIAVALLLKVLALVLIVPGWLTLWMAIFADMGATLLVLLNSLRLLRLDGISKKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 58
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 58
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 57

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GY4MC1_1725 YP_003989110.1 cadmium-translocating P-type ATPase BAC0298 Protein 2e-99 46
GY4MC1_1725 YP_003989110.1 cadmium-translocating P-type ATPase BAC0092 Protein 3e-96 44