Gene Information

Name : GY4MC1_1491 (GY4MC1_1491)
Accession : YP_003988893.1
Strain : Geobacillus sp. Y4.1MC1
Genome accession: NC_014650
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1466408 - 1467925 bp
Length : 1518 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: gyc:GYMC61_2862 aldehyde dehydrogenase

DNA sequence :
ATGGCGACTGTGAAAGAACAAAAAATGGAGAAGCTTGAAACAAAACGTGAAATGTATCATCTGATTATTAACGGGGAGCG
TGTCGAAAGCGCTTCCGGGGAAACGTTTACGACATACAACCCGGCAACAGGGGAGCCGGTTGCGAAAGTAGCGAAAGGAA
CGAAAGAAGATGCGGAACGTGCTATTCAAGCGGCGCGTCAAGCTTTTGATCATGGCAAATGGCGCCATTTTCCTGTCAAC
AAACGGGCGCGTATTTTAAACAAAATTGCTTCTATTATGCGTTCCCGTTTTCATGAGTTAGTAGAATTAGAGATTTTAGA
TACAGGGAAAGCACTTTCCGCCGCACAAGGGCAAGTGATGCAGGCGATTGAAGATTTTGAATTTTACGCCAGTGCCATTA
TCAGCCATCGCGGCACGGTCAACAATATGCCAGGTGCGTTTCATAATTTTACCGAAAAAGAGCCTGTCGGGGTATGTGCG
CAAATTATCCCATGGAATTATCCATTGATGATGGCAGCGTGGAAAATTGCCCCAGCCATTGCAGCAGGGTGTTCCGTTGT
TGTCAAGCCGGCTTCATTAACACCGCTGACATGTATCGTACTTGCAGAAATTTGTCATGAAGCTGGCGTCCCGGAAGGTG
TCGTCAACGTAGTGACCGGGTCTGGCTCTGAAGTCGGGAATTATTTAGTTGAGCATCCGCTTGTTGATAAAGTTGCCTTT
ACTGGTTCGACTCCAGTTGGAAAAAATATTATGGAAAAAGCGTCGAAAACGTTAAAACGGGTAACATTAGAACTCGGCGG
CAAATCGCCGAACATCATCTTCGAGGATGCAGACATTGATGCCGCTGTTAACGGTTCATTATTCGGAATTTTCTATAATA
CCGGACAATCTTGTGAAGCGCGTTCCCGTTTATACGTACATGAAAGCATTTACGATCAATTCATCGAAAAATTTGTTGAA
AAAACGAAAAAATTGAAGCTTGGCAATCCGTTTGAGCAAGATACCCATGTTGGTGCCATCATTAGCCGCGAACAACTAGA
AGTTATTGACGGCTATGTGAAATCTGCCATCGAAGAGGGAGCTACGATTGTCACTGGCGGGAGAAAAGCGAAAGTGGAAG
GGTTTGAAAACGGCTTTTGGTACGAACCAACCATTATTACGGATGTCAATCATCAAATGAAAGTCGTTAAAGAAGAAATT
TTCGGCCCGGTCGTCGTTGTAATGAAATTTAATGATGAAAATGAGGTCATTAAATTGGCTAATGACAGTGAATATGGCTT
GGGATCGGCCATCTGGACAAAAGATCATGCACGTGCGATTCGTGTGGCGAAACAAATTCAAGCTGGTATTGTCATGGTTA
ATAGCCCGTTCTCCGCGTTCCCAGGAACGCCGTTTGGCGGATATAAACAGTCCGGATTCGGACGTGAGCTTTGCATCGAA
ACACTCGACTTATATACGGAAACGAAAAGCATCCTGTCTTATTATGGAAGCCGTCCGCTCAATCCTTTCGGCGTGTAA

Protein sequence :
MATVKEQKMEKLETKREMYHLIINGERVESASGETFTTYNPATGEPVAKVAKGTKEDAERAIQAARQAFDHGKWRHFPVN
KRARILNKIASIMRSRFHELVELEILDTGKALSAAQGQVMQAIEDFEFYASAIISHRGTVNNMPGAFHNFTEKEPVGVCA
QIIPWNYPLMMAAWKIAPAIAAGCSVVVKPASLTPLTCIVLAEICHEAGVPEGVVNVVTGSGSEVGNYLVEHPLVDKVAF
TGSTPVGKNIMEKASKTLKRVTLELGGKSPNIIFEDADIDAAVNGSLFGIFYNTGQSCEARSRLYVHESIYDQFIEKFVE
KTKKLKLGNPFEQDTHVGAIISREQLEVIDGYVKSAIEEGATIVTGGRKAKVEGFENGFWYEPTIITDVNHQMKVVKEEI
FGPVVVVMKFNDENEVIKLANDSEYGLGSAIWTKDHARAIRVAKQIQAGIVMVNSPFSAFPGTPFGGYKQSGFGRELCIE
TLDLYTETKSILSYYGSRPLNPFGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-76 42
hpaE AAO17179.1 HpaE Not tested tcd island Protein 5e-82 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-79 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-79 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-79 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GY4MC1_1491 YP_003988893.1 aldehyde dehydrogenase VFG0082 Protein 8e-77 42