|
Name : clpB (HMPREF0421_20077) Accession : YP_003985186.1 Strain : Gardnerella vaginalis ATCC 14019 Genome accession: NC_014644 Putative virulence/resistance : Virulence Product : chaperone protein ClpB Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 76671 - 79277 bp Length : 2607 bp Strand : - Note : COG: COG0542; Pfam: PF02861,PF00004,PF07724; InterPro: IPR003959 DNA sequence : ATGGGGGTAAATATGGAACAAAAGTTTACAACCTTAGCGCAAGATGCATTAAGCGATGCTGTGCAAAGCGCGGCGGCAGC TGGCAATGCGCAAGTAGATACGTTACATTTGGCAGATGCCTTACTTCGCCAAGAGCAAGGCGTAGTGCGCGCGCTTATTG CACAGACTGGTGCAGATGCGCAACAAATCGGCGCTGAAATTCGCAACGCATTAGTGGCATTGCCTTCATCTACTGGCTCA ACTACAACTAAGCCAGACGCAAGTCGTCAGCTTTTGGCTGCGTTAAGCCAGGCAGAAAAAGAAATGCGCACAATGGGAGA CGAATACGTTTCTACAGAGCACATGCTTATTGGCATAGTTGCAAGCGCGCCGAATGCTGTTGCGGATATTTTCAAAAAGC ACAATGTTTCTGCAGATGCGTTGCGCAAGGCTGTGCCAACTGTGCGCGGAGGCGCGAAAGTTACAAGTCCAGACGCGGAA GGCAACTACAAAGCGCTCGAAAAATATTCTGTTGATATGACTGCGCGCGCTCGCGAAGGAAAGCTTGACCCTGTGATTGG GCGAGATCAGGAGATTCGCCGCGTGATTCAGATTCTTTCTCGCCGCACGAAGAATAATCCTGTGCTAATTGGCGAGCCAG GCGTTGGTAAAACGGCAGTTGTAGAAGGATTGGCTCAGCGAATTGTGGCAGGAGATGTGCCTACGACTTTGCAAAACAAG CGTCTTATCAGTCTCGATTTGGCTTCGATGGTTGCAGGTTCGAAGTATCGTGGCGAATTTGAGGAACGATTAAAGGCAGT GTTGAAGGAAATTCAGCAATCGGACGGTCAAATTATTACGTTTATTGACGAAATTCACACTGTTGTTGGCGCAGGATCTG CAGAAGGTTCAATGGATGCTGGCAATATGCTTAAGCCAATGCTTGCGCGCGGTGAGCTGCGCTTGGTTGGTGCAACTACG CTTAACGAGTATCGCGAGCATATTGAAAAGGATTCGGCGCTTGAACGCAGATTCCAGCAAGTATTTGTTGGCGAGCCATC TGTTGAAGATACGGTGACGATTTTGCGCGGACTTAAGCAACGTTACGAAGCACACCACAAGGTGACGATTAGTGACGATG CAATCGTAGCTGCAGCAACGCTTTCAAACCGCTATATTACTGGTAGACAGCTTCCAGATAAGGCGATTGATTTGGTGGAT GAAGCGGCAGCTCACTTGCGCATGGAGCTTGATTCTCAGCCAGAAGAAATCGACGAATTGCAGCGCAAAGTTACGCGTCT TGAAATGGAAGAAATGCAATTAAAGAAAGCAGAAGATGCTGCTGCTAAAGAACGCTTAGAAAAGTTGCAAGAAGAATTAG CAAACTCGCGCGAAAAGCTTACTGGATTGAAAGCGCGTTGGGATGCGGAAAAAGCTGGCCATAACAAGGTTGGTGATTTG CGAGCGCAACTCGATGCTAAGCGCGTAGAAGCCGACAAATTCACGCGCGAAGGCAATTTGGAGCAGGCAAGCCGTATTTT GTATGGCGAAATTCCAAGCATTCAAAAAGCTTTGGAAGAAGCGGAATCACAGGCTGCTAATGCTAAGAGTGAAGCGAAAG AGCCAATGGTCCCAGACCAGGTTGATGCCGATTCTATTGCAGGAGTTGTTAGCGAATGGACTGGCATTCCTGTTGGTCGC TTAATGCAAGGCGAAAATGAGAAGCTGCTCAACATGGAAAAGGAGCTTTCTAAGCGCGTTGTTGGCCAAAGCGAAGCAAT CCGCGCTATAGCGGATGCTGTGCGCAGAAGCCGTGCTGGAATTGCAGACCCGAATCGCCCAACTGGTTCGTTCCTATTCT TGGGTCCTACTGGCGTTGGTAAGACGGAGCTTGCAAAGGCTCTTGCCGACTTCTTGTTTGACGACGAGCGCGCAATGGTT CGCATTGATATGAGCGAGTACATGGAAAAGGCTTCCGTTTCACGGCTTATAGGTGCTGCTCCTGGTTACATTGGCTATGA GGAAGGCGGCCAGCTTACTGAAGCCGTGCGACGCCGCCCGTATTCTGTAGTGCTTTTTGACGAAATTGAGAAGGCACATC CAGAAGTATTCGACGTTTTGTTGCAGGTTTTGGACGATGGTCGTTTGACTGACGGGCAAGGTAGAACAGTTGATTTTACG AATACGATTTTGATTATGACATCAAACTTGGGTTCGCAATTCCTTGTGCAAGAGGGCTTGGATGATGATGCTAAGCGCAA GGCTGTTATGAACGCTGTTCACGCTGAGTTTAAGCCAGAGTTCATTAACCGTTTGGATGAGCTTGTTATGTTCCATCCGT TGAGCCGCGAAGAGCTTGGCGGAATTGTGGATATTCAAGTTCGTCAAGTGGCTGCACGCTTGAGTGATCGCCGTATTAGC TTGGATGTGAGTGATTCTGCTCGCGCTTGGCTTGCGGAGCATGGCTATGATCCAGTTTACGGTGCTCGTCCGTTGCGTAG ATTGGTTCAAACGGAAATTGGCGATCAACTTGCGCGATTGTTGCTTTCTGGCAAGGTGCATGATGGGGCTCGCGTAGTTG CGGATTGTGAGAATACTAGCGACCATGTAACCCTAAAGATTGCGTAG Protein sequence : MGVNMEQKFTTLAQDALSDAVQSAAAAGNAQVDTLHLADALLRQEQGVVRALIAQTGADAQQIGAEIRNALVALPSSTGS TTTKPDASRQLLAALSQAEKEMRTMGDEYVSTEHMLIGIVASAPNAVADIFKKHNVSADALRKAVPTVRGGAKVTSPDAE GNYKALEKYSVDMTARAREGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQNK RLISLDLASMVAGSKYRGEFEERLKAVLKEIQQSDGQIITFIDEIHTVVGAGSAEGSMDAGNMLKPMLARGELRLVGATT LNEYREHIEKDSALERRFQQVFVGEPSVEDTVTILRGLKQRYEAHHKVTISDDAIVAAATLSNRYITGRQLPDKAIDLVD EAAAHLRMELDSQPEEIDELQRKVTRLEMEEMQLKKAEDAAAKERLEKLQEELANSREKLTGLKARWDAEKAGHNKVGDL RAQLDAKRVEADKFTREGNLEQASRILYGEIPSIQKALEEAESQAANAKSEAKEPMVPDQVDADSIAGVVSEWTGIPVGR LMQGENEKLLNMEKELSKRVVGQSEAIRAIADAVRRSRAGIADPNRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMV RIDMSEYMEKASVSRLIGAAPGYIGYEEGGQLTEAVRRRPYSVVLFDEIEKAHPEVFDVLLQVLDDGRLTDGQGRTVDFT NTILIMTSNLGSQFLVQEGLDDDAKRKAVMNAVHAEFKPEFINRLDELVMFHPLSREELGGIVDIQVRQVAARLSDRRIS LDVSDSARAWLAEHGYDPVYGARPLRRLVQTEIGDQLARLLLSGKVHDGARVVADCENTSDHVTLKIA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 4e-159 | 47 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 1e-108 | 41 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 9e-109 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_003985186.1 | chaperone protein ClpB | VFG2084 | Protein | 1e-111 | 44 |
| clpB | YP_003985186.1 | chaperone protein ClpB | VFG2076 | Protein | 2e-119 | 44 |
