Gene Information

Name : leuS (HMPREF0421_20733)
Accession : YP_003985838.1
Strain : Gardnerella vaginalis ATCC 14019
Genome accession: NC_014644
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 905657 - 908641 bp
Length : 2985 bp
Strand : +
Note : COG: COG0495; Pfam: PF09334,PF00133,PF08264; InterPro: IPR002302

DNA sequence :
ATGGAAGACAACGATCAACAGTATTCAACAGCTGACAATAAAGCTACTATTGCTGAGCCAGCTTTTCGTTACAATGCGCA
GCTCGCACAAGATATTGAGCAGCGCTGGCAAAAGACTTGGGACGAGCAGGGCACGTTCTGGGCTGCTAATGTTAAGGGCG
ATTTGAAGGATGGCGAAGGCAGATTGGCTTGTGGCCGTCCTTCTTTCTTTGCAATGGACATGTTCCCTTATCCTTCTGGA
AAGGGCTTGCATGTTGGACATCCTCTTGGATATTTGGCAACGGATGTTGTGAGCCGATATCACCGTATGAAGGGCGAGAA
TGTTCTTCACGCGATGGGCTACGACGCTTTTGGACTTCCTGCAGAACAATATGCTGTTCAAACAGGTCAGCATCCGCGCA
TTACTACTGAGGCAAATATTGCAAATATGCGCAGGCAGTTGCATCGCATGGGATTGAGCTTTGACGATCGTAGATCTTTT
GCAACTATTGATACAAACTACGTTCGTTGGACTCAATGGATTTTCTCGAAGCTTTATGACGCTTGGTATGACCCTGATTT
TGTACGCAAAGATGGCGGTAAAGGTTCTGCTCGACCAATTGCTGAGTTAGTTGATGAGTTTAAGAGCGCAAAGCGCGAAA
TTCCTGGTTTTGCTGACAAAAAGTGGGGAGAGCTCAATAAAGTAGATCAAGCGGATGTGTTGAATGACTTCCGCATTGCT
TACATTTCTAAGTCTCCTGTAAATTGGTGTCCAGGATTGGGAACTGTGCTTGCAAACGAGGAAGTTACTGCAGAAGGTAA
ATCTGAGCGCGGAAACTTCCCAGTATTCCAGCGCAATCTTCGTCAGTGGTCCATGCGAATTACAGCTTATGCTCATCGCT
TGGTTGAAGATTTGGATACTATTGATTGGCCAGAAAAAGTTAAGCTTATGCAGCGAAACTGGATTGGCGAATCTCACGGT
GCTTCCGTGCATTTTGAAGTTGAATGTGCAGATGGTGAAACGCGCGATTTGGAAGTATACACTACTCGTCCAGATACGCT
TTTTGGTACAACTTTTGCTGTTGTTTCTGTAGATCACCCGATTCTTGAGCACGTTCCAGAAGCGTGGGAAGCTAGCGTTC
CAGAAAGCTGGAAGGGTGGCTACGCAAGCCTTAAGGAAGGATTGGCAGAGTATCAGGCTCAAGCTCGCGCTAAAACCGCT
AAAGATCGTACGGAAGACGCTGGTGCAAAAACTGGTTTGTTTACTGGTCTTTACGCAATTAATCCTGTAACTGGAGCAAA
ACTTCCGCTGTTTGTTGCAGATTATGTGCTTATGGGTTATGGAACGGGCGCAATTATGGCAGTTCCTGGCGGTGACCAGC
GCGATTATGATTTTGCTAAAGCTTTCGGCTTGTCTGTAATTTACACTGTTAAGCCTTTGCCTGATTCTGTCGAAAAGCTA
GAAGATTATGATGGCAAAGCTCCGTTTGTTTCTCACGATGGAATTGTTATTAACTCTTCTGTGGAGCATACTTATAAGCT
CGGTGACGCTTTGTCTATTAACGGTTTGCGCGTAGATGAAGCTATTAAAAAAGTGACGACTTGGCTTGAAGCAGCAGGCG
TAGGCGTTGGTAAGGTTTCTTACAGACTTCGCGATTGGCTGTTCTCTAGGCAGCGCTACTGGGGTGAGCCATTCCCAATC
GTTTATGATGAGGATGGTGTTGCTCACCTTGTGCCGGATAGTGAGCTTCCAATTGCATTGCCAGACGTTCCAGATTATCA
GCCAAAAACTTACGCTCCAGACGACGCAAATTCTGAGCCTGAAGCACCTTTGAGCCGAAACGAGGATTGGGTTAAAGTTC
AGCTTGATCTTGGTGACGGTGTAAAAACCTACTATCGCGACACCAACACTATGCCAAACTGGGCTGGTTCATGCTGGTAT
TACATGCGTTACTTGGATCCAAACGACGCTGAGCATATGGTTGACAGCGACGAATACGACTATTGGATGGGTACGAATCG
ACCAGGCAAGGAACATGTTTCTGGAGGCGTTGACCTTTATGTTGGAGGCGTAGAGCATGCAGTTTTGCACTTGCTTTACT
CGCGCTTCTGGCATAAGGCGCTTTACGACTTGGGTTACGTTGATTCTGCTGAGCCTTTCCATCGCTTGTTTAACCAGGGT
ATGATTCAGGCTTACGCTTACACGGATGAGCGCGGGCAGTACGTGCCAGCTGATGAGGTTGAGGAAGGCGCTAATAACGG
CGTTGGTGAGCCAACATTTACTTGGCACGGCGAAACCGTGAATCGCGAGTTTGGAAAGATGGGCAAGAGCCTAAAGAATA
TTGTGACTCCAGACTACATGTACGAAAATTACGGTGCAGACACGTTCCGTTTGTATGAAATGAGCATGGGTCCACTTTCT
GAGTCTCGCCCATGGAATACGCGTAACGTTGTTGGAGGCATGCGATTCTTGCAACGCTTGTGGCGTAACGTTGTAAACGA
AGAAACTGGCGCTTGCGTAGTAACAGAAGATGCTTTGGACGAAAAGACGCTAAAGCTTCTTAACAACACGATTGTAGAAG
TAACTGTAGAAATGGAAGCAATGCGTCCAAACACTGCGATTGCTAAGCTGATTGTGTTGAATAATCACTTAACGTCTCTG
CCTCACGTGCCTCGCGCAGCAGTTGAGCCGCTTGTTCTTATGCTTTCTCCAATTGCACCGCATATTTGTGAAGAAATGTG
GAGCAAGCTTGGACATACTAAGTCGATTGCTCACGCAGATTGGCCAGTTGAAGATTCCCGCTACGTTGGTGCGGATACTG
TTACAGCTGTTGTACAAATCAAGGGCAAGGTTCGCGCAAAGCTTGAAGTTGACCCGAATATTGATGCTAGTGAGCTTGAA
AAGCTTGCTTTAGAGGCCGTAGCTGATCGCTTGGGTGGAAAGAAGCCGCGCAAGGTAATCGTGAAAGCACCAAAGATTGT
GTCTATTGTGCCAGATGAAAGCTGA

Protein sequence :
MEDNDQQYSTADNKATIAEPAFRYNAQLAQDIEQRWQKTWDEQGTFWAANVKGDLKDGEGRLACGRPSFFAMDMFPYPSG
KGLHVGHPLGYLATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEANIANMRRQLHRMGLSFDDRRSF
ATIDTNYVRWTQWIFSKLYDAWYDPDFVRKDGGKGSARPIAELVDEFKSAKREIPGFADKKWGELNKVDQADVLNDFRIA
YISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRNLRQWSMRITAYAHRLVEDLDTIDWPEKVKLMQRNWIGESHG
ASVHFEVECADGETRDLEVYTTRPDTLFGTTFAVVSVDHPILEHVPEAWEASVPESWKGGYASLKEGLAEYQAQARAKTA
KDRTEDAGAKTGLFTGLYAINPVTGAKLPLFVADYVLMGYGTGAIMAVPGGDQRDYDFAKAFGLSVIYTVKPLPDSVEKL
EDYDGKAPFVSHDGIVINSSVEHTYKLGDALSINGLRVDEAIKKVTTWLEAAGVGVGKVSYRLRDWLFSRQRYWGEPFPI
VYDEDGVAHLVPDSELPIALPDVPDYQPKTYAPDDANSEPEAPLSRNEDWVKVQLDLGDGVKTYYRDTNTMPNWAGSCWY
YMRYLDPNDAEHMVDSDEYDYWMGTNRPGKEHVSGGVDLYVGGVEHAVLHLLYSRFWHKALYDLGYVDSAEPFHRLFNQG
MIQAYAYTDERGQYVPADEVEEGANNGVGEPTFTWHGETVNREFGKMGKSLKNIVTPDYMYENYGADTFRLYEMSMGPLS
ESRPWNTRNVVGGMRFLQRLWRNVVNEETGACVVTEDALDEKTLKLLNNTIVEVTVEMEAMRPNTAIAKLIVLNNHLTSL
PHVPRAAVEPLVLMLSPIAPHICEEMWSKLGHTKSIAHADWPVEDSRYVGADTVTAVVQIKGKVRAKLEVDPNIDASELE
KLALEAVADRLGGKKPRKVIVKAPKIVSIVPDES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-135 45