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Name : thiC (HMPREF0421_20627) Accession : YP_003985732.1 Strain : Gardnerella vaginalis ATCC 14019 Genome accession: NC_014644 Putative virulence/resistance : Unknown Product : thiamine biosynthesis protein Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0422 EC number : 2.5.1.3 Position : 779269 - 781914 bp Length : 2646 bp Strand : - Note : COG: COG0422; Pfam: PF02581,PF01964; InterPro: IPR002817 DNA sequence : ATGACCTCAAACTATCCATACGCATCAATGCGTGACCAGTTCAACCTAAACACATGTTTTATTGCAAATCCTAAACTATG CAAAAGTCGCGCACTCACGGATATAGTTGACGACTCTTTACGCGCAGGATCAACATTTATAAGGCTTAATTGTGCGGATG AAAGCGCAAAAGAAATCACATCAATCGCACGAGATATTGCACAAATCATAGAAGATAACGATAAATGTGATTCAGTAACT TTCGTAATAGACGGAAGAGTTGACGTTGTCTGGCAGGCAAGAAATCAAGGAATTAAAGTCGATGGAGTTCATCTTGCGCA AAGCGACATGGAACCTAAAGAAGCACGAGCACTTTTGGGAGAAGACGCAATAATAGGCTTGTCCGTAGAAACAGAAAGTC TTGTTAAGGTTATTAATGAACTTCCTGATGGCTGCATTGATTATATTTGTGTAACGGCAATGCGTAATCCAGAAGATGGT TGCGAAAACATTACTCCAACTTATGAATTAGAACCAAATCACACTATTTTAGATGTAGCAAAGATTAATACTATTTGCTC AGCAAGCGATTTTCCAGTACTTGTTGGAGGAAGAACATCTTTAGAAGATGTTGACATGATTGCTCGCAGTAAGGCTGCAG GATTGTTTGTATCTGAAGCATTGTACGCAAGCGAAACACCAGAATCCACTATGAGTGAATTCGTGGAACGCTTTACGCAC ATTCGCGGCAATCAAAAGCACGGTTATGCAAAACGCGTTATAGTTCAGGAAAAAGCTGATGAGAAAGCTAACAATACGCC AAAGTTCATTAATGCTAAAGAAGCAAAAGATGCTGCAAAATTAGCAAAGCAACAGCGCGTTGATATTGCTTCTCGCGGAT GTACTCAGAGGGACAAAGCTCATATTCGTAAAACTACGCCAGTTCACTTTGAATATGAATATGGTTCTTACGATTTGGAA GTTCCTTATACAGAAATTAAGCTTTCTGATACTCCAGGCGTTGGCCCTAACCCACCATTTAAGGATTACAACACAGAGGG ACCTAAGTGCGATCCTAAGGAAGGCTTGGCTCCACTTCGTCTTGATTGGATTAGAGATCGTGGCGATGTTGTTGAATATG AAGGTCGTAGTCGAAATCTTCAAGATGACGGCAAGCGAGCTATTAAGCGCGGTAAAGCTTCAAAAGAGTGGCGTGGTCGC ACTCATAAGCCAATGAAGGCTGCAGATCATCCTATTACCCAAATGTGGTACGCGCGTCATGGAATTATCACTCCAGAAAT GCAGTATGTTGCTACTCGCGAAAATTGCGATGTGGAACTTGTTCGCTCTGAAGTTGCATCTGGTCGCGCTGTGATTCCTT GCAATATCAACCACCCTGAAGCAGAACCTATGATTATTGGTTCTCGCTTCTTAACTAAGCTCAATGCCAACATGGGTAAT TCTGCTGTAACATCTTCTATTGACGAAGAAGTAGAAAAACTTACGTGGGCTACTAAGTGGGGTGCAGATACCGTTATGGA TCTTTCCACAGGTAACGATATTCACACAACTCGCGAGTGGATTTTGCGTAACTCCCCTGTTCCGATTGGTACCGTGCCAA TGTATCAAGCTTTGGAAAAAGTTGAGGATGATGCTTCTAAGCTCAGCTGGGAGCTTTTCCGCGACACTGTTATTGAACAG TGCGAGCAAGGCGTTGACTACATGACTATTCACGCAGGCGTACTTCTTCGCTACGTGCCTCTTACTGCAAACCGCGTAAC TGGTATTGTTTCTCGAGGCGGATCCATTATGGCTGAATGGTGCTTGCAACACCATCAAGAAAGCTTCTTATACACTCACT TCGAAGAATTATGTGAGATTTTCGCCAAGTACGATGTTGCATTCTCTTTGGGAGATGGTTTACGACCAGGAAGCTTGGCT GATGCTAACGATGCTGCTCAGCTTTCTGAGCTTATGACGCTTGGTGAACTTACTAAGATTGCTTGGCAACACGATGTTCA GGTTATGATTGAAGGACCAGGACACGTACCATTTGATACGGTACGCATGAATATTGAAATGGAGAAAGCAATTTGCCAAA ATGCTCCATTCTATACTCTTGGTCCTTTAACAACCGATACTGCACCAGGATATGATCACATTACTTCCGCTATCGGCGGC GTTGAAATCGCTCGTTATGGTACGGCAATGCTTTGCTACGTCACTCCTAAAGAGCATTTAGGACTTCCTAATAAGGATGA CGTTAAACAAGGTGTTATTGCTTATAAGATTGCTTGTCACGCTGCGGATCTTGCTAAGCATCATCCGCATGCCATGGATA GAGATAACGCTATAAGCAAGGCTCGTTTCGAGTTTCGCTGGCTGGATCAGTTTAATTTAAGCTACGATCCAGATACCGCT ATCGCTTTCCATGACGAAACGCTTCCAGCAGAGCCAGCAAAAATGGCTCACTTCTGTTCCATGTGTGGACCAAAATTCTG CTCAATGGCTATTTCTCAGAATATTCGCAAGCGTTTCGGTGGCGCAGATCAACAAGAACAACTTGTTGAAGAAGCCCGCA GTCAGGCTATTGCCGAGGGTATGAAAGAGATGAGTAAAAAGTTCCAGGAAGCTGGTTCAACGTTGTATCAAAGCGCCAAA GCGTAG Protein sequence : MTSNYPYASMRDQFNLNTCFIANPKLCKSRALTDIVDDSLRAGSTFIRLNCADESAKEITSIARDIAQIIEDNDKCDSVT FVIDGRVDVVWQARNQGIKVDGVHLAQSDMEPKEARALLGEDAIIGLSVETESLVKVINELPDGCIDYICVTAMRNPEDG CENITPTYELEPNHTILDVAKINTICSASDFPVLVGGRTSLEDVDMIARSKAAGLFVSEALYASETPESTMSEFVERFTH IRGNQKHGYAKRVIVQEKADEKANNTPKFINAKEAKDAAKLAKQQRVDIASRGCTQRDKAHIRKTTPVHFEYEYGSYDLE VPYTEIKLSDTPGVGPNPPFKDYNTEGPKCDPKEGLAPLRLDWIRDRGDVVEYEGRSRNLQDDGKRAIKRGKASKEWRGR THKPMKAADHPITQMWYARHGIITPEMQYVATRENCDVELVRSEVASGRAVIPCNINHPEAEPMIIGSRFLTKLNANMGN SAVTSSIDEEVEKLTWATKWGADTVMDLSTGNDIHTTREWILRNSPVPIGTVPMYQALEKVEDDASKLSWELFRDTVIEQ CEQGVDYMTIHAGVLLRYVPLTANRVTGIVSRGGSIMAEWCLQHHQESFLYTHFEELCEIFAKYDVAFSLGDGLRPGSLA DANDAAQLSELMTLGELTKIAWQHDVQVMIEGPGHVPFDTVRMNIEMEKAICQNAPFYTLGPLTTDTAPGYDHITSAIGG VEIARYGTAMLCYVTPKEHLGLPNKDDVKQGVIAYKIACHAADLAKHHPHAMDRDNAISKARFEFRWLDQFNLSYDPDTA IAFHDETLPAEPAKMAHFCSMCGPKFCSMAISQNIRKRFGGADQQEQLVEEARSQAIAEGMKEMSKKFQEAGSTLYQSAK A |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thiC | YP_001598318.1 | thiamine biosynthesis protein ThiC | Not tested | MDA | Protein | 1e-155 | 55 |
