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Name : guaA (HMPREF0421_20578) Accession : YP_003985683.1 Strain : Gardnerella vaginalis ATCC 14019 Genome accession: NC_014644 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 716223 - 717785 bp Length : 1563 bp Strand : + Note : COG: COG0519; Pfam: PF00117,PF03054,PF00958; InterPro: IPR001674 DNA sequence : ATGGCAAAAGGTCCGGTACTTGTAGTTGACTTCGGTGCCCAATATGCCCAGCTAATCGCTAGAAGAGTGAGGGAAGCAAA CGTTTATTCGGAGCTTGTTCCACACTCTATGCCTGTAGAAGAAATGCTGGCAAAAGATCCAAAAGCCATAATTCTCTCTG GCGGGCCTGCTTCCGTTTATGAACCAGGAGCGCCAAAAATTGACACAAAGATTTTTGAAGCAGGAGTTCCAGTGCTCGGA ATTTGCTACGGATTCCAAGTTATGGCTCATGAGCTTGGCGGAGTCGTAGACAAAGCCGCATTGGGTGAGTATGGAAAAAC GCATGCAACTATTGATGAAGCAGAAGGATTGCTTGCTAATTCTCCATTAGATCAAAATACTTGGATGAGTCACGGAGTGG CAGTTAAGAGCGTGCCAGAAGGATTTGAGGTGCTTGCTCACACTCAAGGTGCTCCAGTTGCAGCTATGCAAGATAAAAGT CGCAAGCTTTACGGAGTGCAATGGCATCCAGAAGTCAAGCATACGCCTTTAGGTCAAAAGCTGATTTCCACATTTTTGCA CGAGTGCGCAGGATTGGAAAATGATTGGAATCCTTCGAATATTATAGAAGATCAGGTTGCAAAGATTCGCGCTGAAGTTG GAGATGCACAAGTTATTTGCGGACTTTCTGGAGGAGTAGATTCCGCAGTTGCAGCAGCACTGGTACATAAAGCAATCGGA GATCAGCTCACTTGCGTTTTTGTAGACCATGGCCTTCTCCGTAAAGGCGAAGTTGAGCAAGTGAAGCACGATTTTGTTGA GGCCACTGGAATCAAGCTTATTGCAGTGGATGCAGAAGATGACTTTTTAGATGCGCTTAAAGGCGTGAGTGAGCCAGAGC GCAAGCGCAAGATTATTGGCGAAAAGTTTATTCGCACATTTGAAAAAGCGCAACGTCAAGTTATTGAAGAAGCTGGAAAA TCTGGAGCAGAAGTTAAGTTCCTTGTACAAGGCACACTTTACCCAGATGTTGTGGAATCTGGTGGCGGAGACGGTGCTGC AAACATTAAGTCGCATCACAATGTTGGCGGCTTGCCAAAGGACTTAAAGTTTAAGCTTATTGAGCCTTTACGCACTTTGT TTAAGGATGAAGTTCGCGCAATTGGTACGGAGCTTGGGCTTCCAGACGCTATTGTGTGGCGCCAGCCGTTCCCAGGCCCA GGATTGGGAATTCGCATTGTTGGCGAGATTACTCGCGAGCGTTTAGCTGTTCTTAGAGAAGCAGATGCGATTGCGCGCGA AGAGCTTTCGGCAGCTGGATTAGATCGCGATATTTGGCAATGCCCAGTTGTTCTTTTGGCAGATGTTCACTCTGTTGGAG TTCAAGGAGACGAGCGCACATATGGATCTCCAATTGTGCTTCGACCAGTAAGTTCTGAGGATGCTATGACTGCTGATTGG TCGCGAGTTCCTTACGATGTATTGGCAAAGATTTCTACTCGAATCACAAACGAATGTCGCCAGATTAATCGCGTTGTGTT AGACGTTACATCTAAGCCGCCTGCCACAATCGAGTGGGAATAG Protein sequence : MAKGPVLVVDFGAQYAQLIARRVREANVYSELVPHSMPVEEMLAKDPKAIILSGGPASVYEPGAPKIDTKIFEAGVPVLG ICYGFQVMAHELGGVVDKAALGEYGKTHATIDEAEGLLANSPLDQNTWMSHGVAVKSVPEGFEVLAHTQGAPVAAMQDKS RKLYGVQWHPEVKHTPLGQKLISTFLHECAGLENDWNPSNIIEDQVAKIRAEVGDAQVICGLSGGVDSAVAAALVHKAIG DQLTCVFVDHGLLRKGEVEQVKHDFVEATGIKLIAVDAEDDFLDALKGVSEPERKRKIIGEKFIRTFEKAQRQVIEEAGK SGAEVKFLVQGTLYPDVVESGGGDGAANIKSHHNVGGLPKDLKFKLIEPLRTLFKDEVRAIGTELGLPDAIVWRQPFPGP GLGIRIVGEITRERLAVLREADAIAREELSAAGLDRDIWQCPVVLLADVHSVGVQGDERTYGSPIVLRPVSSEDAMTADW SRVPYDVLAKISTRITNECRQINRVVLDVTSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-170 | 67 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-140 | 54 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-140 | 54 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 1e-140 | 54 |
